2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (7658):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-14397S2
    Indometacin-d7
    Indometacin-d7 is deuterated labeled Indomethacin (HY-14397). Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin has anticancer activity and anti-infective activity. Indomethacin can be used for cancer, inflammation and viral infection research.
    Indometacin-d<sub>7</sub>
  • HY-106254S1
    Vapendavir-d6
    Vapendavir-d6 (BTA798-d6) is deuterium-labeled Vapendavir (HY-106254).
    Vapendavir-d<sub>6</sub>
  • HY-W654010
    Lurasidone-d8-1 hydrochloride
    Lurasidone-d8-1 (hydrochloride) is deuterium labeled Lurasidone (Hydrochloride). Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is an antagonist of both dopamine D2 and 5-HT7 with IC50s of 1.68 and 0.495 nM, respectively. Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is also a partial agonist of 5-HT1A receptor with an IC50 of 6.75 nM.
    Lurasidone-d<sub>8</sub>-1 hydrochloride
  • HY-W727768
    Salicylic acid 2-O-β-D-glucoside-d4
    Salicylic acid 2-O-β-D-glucoside-d4 is deuterium labeled Salicylic acid 2-O-β-D-glucoside.
    Salicylic acid 2-O-β-D-glucoside-d<sub>4</sub>
  • HY-132508S
    Etravirine-d8
    Etravirine-d8 is the deuterium labeled Etravirine. Etravirine (R165335) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV[1][2].
    Etravirine-d<sub>8</sub>
  • HY-W755036
    Oxytetracycline-13C,d3 hydrochloride
    Oxytetracycline-13C,d3 hydrochloride is the 13C- and deuterium labeled Oxytetracycline hydrochloride (HY-B0275A). Oxytetracycline hydrochloride is an antibiotic that exhibits board-spectrum antibacterial activity. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti-HSV-1 activity.
    Oxytetracycline-<sup>13</sup>C,d<sub>3</sub> hydrochloride
  • HY-B0411S2
    Domperidone-13C6
    Domperidone-13C6 (R33812-13C6) is 13C labeled Domperidone. Domperidone (R33812) is an orally active and selective dopamine-2 receptor antagonist. Domperidone acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine.
    Domperidone-<sub>13</sub>C<sub>6</sub>
  • HY-14291S5
    Vildagliptin-d6
    Vildagliptin-d6 (LAF237-d6 ) is deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity.
    Vildagliptin-d<sub>6</sub>
  • HY-16935S
    Mavatrep-d6
    Mavatrep-d6 (JNJ-39439335-d6) is a deuterated labeled Mavatrep (HY-16935). Mavatrep (JNJ-39439335) is an orally active, selective and potent TRPV1 antagonist with high affinity for hTRPV1 channels (Ki=6.5 nM). Mavatrep antagonizes capsaicin-induced Ca2+ influx with an IC50 value of 4.6 nM. Mavatrep can be used in some studies of neuropathic pain.
    Mavatrep-d<sub>6</sub>
  • HY-B0982S
    Pindolol-d7
    Pindolol-d7 (LB-46-d7) is the deuterium labeled Pindolol. Pindolol (LB-46) is the antagonist for 5-HT 1A (Ki=33 nM) and 5-HT 1B. Pindolol is the antagonist for β1/β2-adrenergic receptor. Pindolol exhibits anti-anxiety and antidepressant effects.
    Pindolol-d<sub>7</sub>
  • HY-W718472S
    3,3′-Dichloro biphenyl-13C12
    3,3′-Dichloro biphenyl-13C12 is 13C labeled 3,3'-Dichloro-1,1'-biphenyl.
    3,3′-Dichloro biphenyl-<sup>13</sup>C<sub>12</sub>
  • HY-W653751
    2-Benzothiazolethiol-d4
    2-Benzothiazolethiol-d4 is the deuterium labeled 2-Benzothiazolethiol-d4 (HY-W653751).
    2-Benzothiazolethiol-d<sub>4</sub>
  • HY-157071S
    Seliciclib Carboxylic Acid-d7
    Seliciclib Carboxylic Acid-d7 is deuterium-labeled Seliciclib Carboxylic Acid.
    Seliciclib Carboxylic Acid-d<sub>7</sub>
  • HY-P3207S
    DLPLTFGGGT-Lys13C6,15N2 TFA
    DLPLTFGGGT-Lys-13C6,15N2 (TFA) is a deuterated labeled DLPLTFGGGTK.
    DLPLTFGGGT-Lys<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>2</sub> TFA
  • HY-N5060S
    Estragole-d4
    Estragole-d4 is deuterated labeled S-Phenyl-d5-mercapturic Acid (HY-W654314). S-Phenyl is deuterated labeled S-Phenyl.
    Estragole-d<sub>4</sub>
  • HY-W723876
    2-Phenyl-d5-ethylamine
    2-Phenyl-d5-ethylamine is deuterium labeled 2-Phenyl-ethylamine.
    2-Phenyl-d<sub>5</sub>-ethylamine
  • HY-N7844S
    N6-Benzyladenosine-d5
    N6-Benzyladenosine-d5 (Benzyladenosine-d5) is deuterium labeled N6-Benzyladenosine. N6-Benzyladenosine is an adenosine receptor agonist, has a cytoactive activity. N6-Benzyladenosine arrests cell cycle at G0/G1 phase and induces cell apoptosis. N6-Benzyladenosine also exerts inhibitory effect on T. gondii adenosine kinase and glioma.
    N6-Benzyladenosine-d<sub>5</sub>
  • HY-W010031S1
    1-Methyluric acid-d3
    1-Methyluric acid-d3 is the deuterium labeled 1-Methyluric acid (HY-W010031). 1-Methyluric acid acts on the urinary bladder mucosa and increases the blood glucose, insulin, triglyceride, and cholesterol levels.
    1-Methyluric acid-d3
  • HY-W780150
    1-Bromobenzene-13C6
    1-Bromobenzene-13C6 is a deuterated labeled 1-Bromobenzene-13C6.
    1-Bromobenzene-<sup>13</sup>C<sub>6</sub>
  • HY-B0696AS
    Tiagabine-d4 hydrochloride
    Tiagabine-d4 hydrochloride is deuterated labeled Tiagabine hydrochloride (HY-B0696A). Tiagabine hydrochloride is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC50s of 67, 446 and 182 nM for [3H]GABA uptake in Synaptosomes, Neurons and Glia, respectively.
    Tiagabine-d<sub>4</sub> hydrochloride