2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (9621):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N7032S
    Uridine 5′-diphosphoglucose-13C disodium
    Uridine 5′-diphosphoglucose-13C (UDP-D-Glucose-13C) disodium is the 13C labeled Uridine 5′-diphosphoglucose disodium (HY-N7032). Uridine 5’-diphosphoglucose (UDP-glucose) disodium, secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose disodium is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose disodium is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue.
    Uridine 5′-diphosphoglucose-<sup>13</sup>C disodium
  • HY-B0833S1
    Thiamethoxam-d3
    		99.00%
    Thiamethoxam-d3 is the deuterium labeled Thiamethoxam. Thiamethoxam is a broad spectrum neonicotinoid insecticide.
    Thiamethoxam-d<sub>3</sub>
  • HY-12389S
    8-Hydroxy amoxapine-d8
    8-Hydroxy amoxapine-d8 is the deuterium labeled 8-Hydroxy amoxapine.
    8-Hydroxy amoxapine-d<sub>8</sub>
  • HY-N2037AS1
    Higenamine-d4-1 hydrochloride
    Higenamine-d4-1 (Norcoclaurine-d4-1) hydrochloride is deuterium labeled Higenamine (hydrochloride). Higenamine hydrochloride is a selective LSD1 inhibitor (IC50=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases.
    Higenamine-d<sub>4</sub>-1 hydrochloride
  • HY-B0965S
    Thioridazine-d3 2-Sulfone
    Thioridazine-d3 2-Sulfone is the deuterium labeled Thioridazine hydrochloride. Thioridazine hydrochloride, an orally active antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities. Thioridazine hydrochloride is also a potent inhibitor of PI3K-Akt-mTOR signaling pathways with anti-angiogenic effect. Thioridazine hydrochloride shows antiproliferative and apoptosis induction effects in various types of cancer cells, with specificity on targeting cancer stem cells (CSCs).
    Thioridazine-d3 2-Sulfone
  • HY-W086988S
    5-Methyl-1H-benzotriazole-d3
    5-Methyl-1H-benzotriazole-d6 (5-Methylbenzotriazole-d6) is the deuterium labeled 5-Methyl-1H-benzotriazole (HY-W086988). 5-Methyl-1H-benzotriazole is a biological material or organic compound that can be used in life science research.
    5-Methyl-1H-benzotriazole-d<sub>3</sub>
  • HY-12772S3
    Hydroxy Itraconazole-d6
    Hydroxy Itraconazole-d6 (R-63373-d6) is deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
    Hydroxy Itraconazole-d<sub>6</sub>
  • HY-W015854S
    Ethyl methanesulfonate-d5
    		99.48%
    Ethyl methanesulfonate-d5 is the deuterium labeled Ethyl methanesulfonate.
    Ethyl methanesulfonate-d<sub>5</sub>
  • HY-142196S
    Betamethasone 17-propionate-d5
    Betamethasone 17-propionate-d5 is the deuterium labeled Betamethasone 17-propionate.
    Betamethasone 17-propionate-d<sub>5</sub>
  • HY-N0112S
    Dihydromyricetin-d4
    Dihydromyricetin-d4 (Ampelopsin-d4) is deuterium labeled Dihydromyricetin. Dihydromyricetin is a potent inhibitor with an IC50 of 48 μM on dihydropyrimidinase. Dihydromyricetin can activate autophagy through inhibiting mTOR signaling. Dihydromyricetin suppresses the formation of mTOR complexes (mTORC1/2). Dihydromyricetin is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 22 μM.
    Dihydromyricetin-d<sub>4</sub>
  • HY-B0158S8
    Cytidine-d13
    Cytidine-d13 (Cytosine β-D-riboside-d13; Cytosine-1-β-D-ribofuranoside-d13) is deuterium labeled Cytidine (HY-B0158). Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function.
    Cytidine-d<sub>13</sub>
  • HY-N0121S
    Sesamin-d8
    Sesamin-d8 is the deuterium labeled Sesamin (HY-N0121). Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia.
    Sesamin-d<sub>8</sub>
  • HY-N0684S4
    Vitamin K1-d3
    Vitamin K1-d3 (Phylloquinone-d3; Phytomenadione-d3) is deuterium-labeled Vitamin K1 (HY-N0684).
    Vitamin K1-d<sub>3</sub>
  • HY-127035S1
    Tristearin-13C3
    Tristearin-13C3 (Glycerol tristearate-13C3) is 13C labeled Tristearin. Tristearin is a triglyceride derived from three units of stearic acid.
    Tristearin-13C3
  • HY-17605S1
    Bictegravir-d5
    Bictegravir-d5 is deuterated labeled Bictegravir (HY-17605). Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM.
    Bictegravir-d<sub>5</sub>
  • HY-132432S
    N10-Monodesmethyl Rizatriptan-d3
    N10-Monodesmethyl Rizatriptan-d3 is the deuterium labeled N10-Monodesmethyl Rizatriptan.
    N10-Monodesmethyl Rizatriptan-d<sub>3</sub>
  • HY-N11142S
    Gb3-d7 (18:1/18:0)
    Gb3-d7 (18:1/18:0) (C18 Globotriaosylceramide-d7 (d18:1/18:0)) is deuterium labeled Gb3(18:1/18:0). Gb3(18:1/18:0) (C18 Globotriaosylceramide (d18:1/18:0)) is an ester product.
    Gb3-d<sub>7</sub> (18:1/18:0)
  • HY-W744953
    Carbimazole-d3
    Carbimazole-d3 is deuterium labeled Carbimazole. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research.
    Carbimazole-d<sub>3</sub>
  • HY-167593S
    C18:0-d7 GM1 Ceramide
    C18:0-d7 GM1 Ceramide is deuterium labeled C18:0 GM1 Ceramide.
    C18:0-d<sub>7</sub> GM1 Ceramide
  • HY-W743562
    Crotamiton-d5
    Crotamiton-d5 is deuterium-labeled Crotamiton (HY-B1177).
    Crotamiton-d<sub>5</sub>