Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (2)

Isotope-Labeled Compounds Related Products (9621):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-19569S1

Upadacitinib-d₅
Upadacitinib-d₅ is the deuterium labeled Upadacitinib. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified.

HY-W654209

Glycopyrrolate iodide-d₃ (mixture of diastereomers)
Glycopyrrolate iodide-d₃ (mixture of diastereomers) is deuterium labeled 3-(2-Cyclopentyl-2-hydroxy-2-phenylacetoxy)-1,1-dimethylpyrrolidin-1-ium iodide.

HY-10570S3

Nevirapine-d₅
Nevirapine-d₅ (BI-RG 587-d₅) is deuterium labeled Nevirapine. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a K_i of 270 μM.

HY-173087S

TPPSSGEPPKSGDR-(Arg-¹³C₆,¹⁵N₄) TFA
TPPSSGEPPKSGDR-(Arg-¹³C₆,¹⁵N₄) TFA is a is the ¹³C- and ¹⁵N-labeled TPPSSGEPPKSGDR-(Arg) TFA.

HY-90009BS

cis-Tadalafil-d₃
cis-Tadalafil-d₃ is the deuterium labeled cis-Tadalafil[1].

HY-121467S

Acotiamide-d₆
Acotiamide-d₆ is a deuterium labeled Acotiamide. Acotiamide is an orally active and first-in-class gastroprokinetic agent for the treatment of functional dyspepsia.

HY-30237S

(R)-Roscovitine-d₇
(R)-Roscovitine-d₇ (Seliciclib-d₇; CYC202-d₇) is deuterium-labeled (R)-Roscovitine (HY-30237).

HY-W004681S

5-Hydroxy-2-methylpyridine-d₆
5-Hydroxy-2-methylpyridine-d₆ is the deuterium labeled 5-Hydroxy-2-methylpyridine.

HY-W714205S

Desethyl terbumeton-d₃
Desethyl terbumeton-d₃ is deuterium labeled N2-(Tert-butyl)-6-methoxy-1,3,5-triazine-2,4-diamine.

HY-B0477AS1

Quinapril-d₅ hydrochloride
Quinapril-d₅ hydrochloride (CI-906-d₅) is the deuterium labeled Quinapril hydrochloride. Quinapril hydrochloride (CI-906) is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications.

HY-142275S

(-)-Nebivolol-d₄ hydrochloride
(-)-Nebivolol-d₄ (hydrochloride) is the deuterium labeled (-)-Nebivolol hydrochloride.

HY-137255S

Taurolithocholic Acid-3-Sulfate-d₄ disodium salt
Taurolithocholic Acid-3-Sulfate-d₄ （disodium salt） is the deuterium labeled Taurolithocholic Acid-3-Sulfate.

HY-150661S

3-epi-Calcifediol-¹³C₅
3-Epi-25-hydroxyvitamin D3-¹³C₅ is the ¹³C labeled 3-Epi-25-hydroxyvitamin D3.

HY-110382S

¹³C₂₀,¹⁵N₁₀-Cyclic di-GMP sodium
¹³C20,¹⁵N10-Cyclic di-GMP (¹³C20,¹⁵N10-c-di-GMP) is ¹³C and ¹⁵N labeled Cyclic-di-GMP (disodium). Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP disodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP disodium can be used in cancer research.

HY-113041S

Prostaglandin A2-d₄
Prostaglandin A2-d₄ is the deuterium labeled Prostaglandin A2.

HY-B1948AS

Diclopentezol-d₉
Diclopentezol-d₉ is deuterium labeled Diclopentezol.

HY-132490S

5-Hydroxy Buspirone-d₈
5-Hydroxy Buspirone-d₈ is the deuterium labeled 5-Hydroxy Buspirone.

HY-18252S3

Avanafil-¹³C₅
Avanafil-¹³C₅ (TA1790-¹³C₅) is ¹³C labeled Avanafil. Avanafil (TA-1790) is a potent and selective phosphodiesterase-5 (PDE-5) inhibitor with IC₅₀ values of 5.2 nM, 630 nM, 5700 nM, 6200 nM, 12000 nM, 27000 nM, 51000 nM and 53000 nM for PDE-5, PDE-6, PDE-4, PDE-10, PDE-8, PDE-7, PDE-2 and PDE-1, respectively. Avanafil activates NO/cGMP/PKG signaling-pathway to decrease loss in BMD, bone atrophy, and oxidative stress. Avanafil inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Avanafil can be used for the research of erectile dysfunction and osteoporosis.

HY-165677S

C22 Galactosylceramide-d₄
C22 Galactosylceramide-d₄ is deuterium labeled C22 Galactosylceramide. C22 Galactosylceramide is a sphingolipid present in the central nervous system, exhibiting elevated levels in the spinal cord of mice on a methionine-restricted diet, while not affecting the brain or liver; furthermore, it has been identified in the postmortem hippocampus of Alzheimer's disease patients.

HY-W721117

N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine-d₃
N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine-d₃ (Methyl N-acetyl-S-(3-hydroxypropyl)-L-cysteinate-d₃) is the deuterium labeled N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine.

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