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Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1340):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-19590
    Etarotene
    Etarotene (Ro 15-1570) is a derivative of Arotinoid (HY-106735). Etarotene is an orally active antitumor agent against DMBA (HY-W011845)-induced mammary tumor and causes toxic symptoms of hypervitaminosis A in rat model.
    Etarotene
  • HY-169500
    Mitomycin Z
    Mitomycin Z (9a-O-Demethylmitomycin G) is a member of the mitomycin family with an antitumor activity.
    Mitomycin Z
  • HY-P10490
    (D-His(Bzl)6)-LHRH (1-7) free acid
    (D-His(Bzl)6)-LHRH (1-7) free acid is a synthetic peptide compound that is a derivative of luteinizing hormone-releasing hormone (LHRH). (D-His(Bzl)6)-LHRH (1-7) free acid enhances its stability and biological activity by introducing unnatural amino acid residues at specific positions of the LHRH molecule. This modification can improve the drug's performance in the body half-life, reducing the rate at which it is rapidly metabolized and cleared, thereby enhancing its efficacy in inhibiting cell proliferation.
    (D-His(Bzl)6)-LHRH (1-7) free acid
  • HY-121951
    N-Methylquipazine
    N-Methylquipazine is an active compound.
    N-Methylquipazine
  • HY-129552
    WAY-855
    WAY-855 is an active compound.
    WAY-855
  • HY-139093
    Paracetamol-cysteine
    Paracetamol-cysteine is a Paracetamol-cysteine Paracetamol protein adduct (PPA) and is formed when paracetamol is oxidized to the reactive metabolite N-acetyl-p-benzoquinoneimine (NAPQI).
    Paracetamol-cysteine
  • HY-P2269
    MAIT-203
    MAIT-203, a cyclopentyalanin-derived peptidomimetic, potently inhibits the interaction of adenomatous polyposis coli (APC) and Asef (RhoGEF4), but not APC-Sam68 or APC-striatin interactions. MAIT-203 binds APC-ARM with a Ki of 0.015 μM and a Kd of 0.036 μM. MAIT-203 significantly represses the migration and invasion of colorectal cancer cells.
    MAIT-203
  • HY-47821
    WAY-655978
    ≥98.0%
    WAY-655978 is an active molecule.
    WAY-655978
  • HY-118809
    J 2931
    J 2931 is an active compound.
    J 2931
  • HY-124145
    Metfendrazine
    Metfendrazine is an active compound.
    Metfendrazine
  • HY-47595
    WAY-621089
    ≥98.0%
    WAY-621089 is an active molecule for the study of amyloid diseases and synucleinopathies.
    WAY-621089
  • HY-163078
    C2-Gal-Dox
    C2-Gal-Dox is a galactose conjugate with high cytotoxicity. C2-Gal-Dox inhibits the growth of a variety of cancer cells.
    C2-Gal-Dox
  • HY-W010562R
    2-Methoxypyrazine (Standard)
    2-Methoxypyrazine (Standard) is the analytical standard of 2-Methoxypyrazine. This product is intended for research and analytical applications. 2-Methoxypyrazine is an active compound. 2-Methoxypyrazine can be used for the research of various biochemical studies[1].
    2-Methoxypyrazine (Standard)
  • HY-105912
    ONO 1082
    ONO 1082 is a Prostaglandin E1 (PGE1) (HY-B0131) derivative and increases cAMP level in hepatocytes. ONO 1082 competes with the action of the cholestatic factor through the increase in the cAMP level.
    ONO 1082
  • HY-129864A
    4-APDB hydrochloride
    4-APDB hydrochloride is a benzofuran.
    4-APDB hydrochloride
  • HY-W720736
    Tinazoline
    Tinazoline, imidazole derivative, is a vasoconstrictor. Tinazoline can as nasal decongestant for the research of common cold.
    Tinazoline
  • HY-116802
    Bromobutide
    Bromobutide is an active compound.
    Bromobutide
  • HY-124395
    MS2126
    MS2126 is an active compound.
    MS2126
  • HY-101719
    Ketocaine
    Ketocaine is a butyrophenone derivative used topically for pain relief.
    Ketocaine
  • HY-114002
    Anticancer agent 129
    99.01%
    Anticancer agent 129 (Compound 3a), a quinoline derivative, predicting to has anti-cancer activity.
    Anticancer agent 129