2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1533):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-124929
    Mimocin
    Mimocin is an active compound.
    Mimocin
  • HY-49065
    WAY-658494
    WAY-658494 is an active molecule.
    WAY-658494
  • HY-168736
    CRC-IN-1
    CRC-IN-1 (compound (-)-15h) is a potent anti-colorectal cancer (CRC) agent, as well as a derivative of the anticancer agent Evodiamine (HY-N0114).
    CRC-IN-1
  • HY-W585893R
    Endrin ketone (Standard)
    Endrin ketone (Standard) is the analytical standard of Endrin ketone. This product is intended for research and analytical applications. Endrin ketone is an Endrin degradation product. Endrin is a carcinogen.
    Endrin ketone (Standard)
  • HY-175846
    TQFL13
    TQFL13 is derivative of Thymoquinone (TQ) (HY-D0803) with potent anti-breast cancer activity. TQFL13 exhibits higher cytotoxicity against breast cancer cells (BT549, MDA-MB-231, 4T1). TQFL13 increases apoptosis and blocks the cell cycle at S and G2/G1 phases in breast cancer cells. TQFL13 shows dose-dependent anti-tumor efficacy in mouse breast cancer allograft model. TQFL13 can be used for the study of breast cancer.
    TQFL13
  • HY-129313
    LG 6-102
    LG 6-102 is an active compound.
    LG 6-102
  • HY-134280
    8-Br-NHD+
    8-Br-NHD+ (Nicotinamide 8-Br-hypoxanthine dinucleotide) is a derivative of NAD+ (nicotinamide adenine dinucleotide) that acts as a potential substrate, competitive inhibitor or modulator of enzymes that interact with β-NAD+. 8-Br-NHD+ can be used to synthesize a cyclic ADP nucleotide (cADPR) analog.
    8-Br-NHD+
  • HY-P10885
    Lead-lapemelanotide zapixetan
    Lead-lapemelanotide zapixetan is a precursor of lapemelanotide, which can be used in life science research.
    Lead-lapemelanotide zapixetan
  • HY-173584
    GSK484-Ph
    GSK484-Ph (compound 15d) is an analog of GSK484 (HY-100514) with potent anticancer effects. GSK484-Ph potently inhibits 4T1 cells and can be used for the study of breast cancer.
    GSK484-Ph
  • HY-W740221
    7-Ethylcamptothecin-d3-1
    7-Ethylcamptothecin-d3-1 is the deuterium labeled 7-Ethylcamptothecin (HY-N2108). 7-Ethylcamptothecin is a derivative of Camptothecin (HY-16560) and a key intermediate in the synthesis of SN-38 (HY-13704). 7-Ethylcamptothecin can be used in tumor-related research.
    7-Ethylcamptothecin-d<sub>3</sub>-1
  • HY-N16131
    Sydonic acid
    Sydonic acid is a bisabolane-type sesquiterpenoid that can be isolated from the fungus Aspergillus sydowii BTBU20213012, which was obtained from a marine sediment sample in the Western Pacific.
    Sydonic acid
  • HY-122036
    Flumedroxone acetate
    Flumedroxone acetate is an active compound.
    Flumedroxone acetate
  • HY-W674612
    WAY-297848
    		≥98.0%
    WAY-297848 is an active molecule for the study of amyloid diseases and synucleinopathies.
    WAY-297848
  • HY-120151
    3,5-Dinitro-p-toluic acid
    3,5-Dinitro-p-toluic acid is an active compound.
    3,5-Dinitro-p-toluic acid
  • HY-151342
    Ser@TPP@CUR
    Ser@TPP@CUR is a Curcumin (HY-N0005) derivative. Ser@TPP@CUR effectively ameliorates injured renal tubular epithelial cells and improves renal functions of acute kidney injury (AKI) mice. Ser@TPP@CUR can be used for the research of AKI .
    Ser@TPP@CUR
  • HY-129581
    Org 27759
    Org 27759 is an active compound.
    Org 27759
  • HY-177270
    CHNQD-01281
    CHNQD-01281, a derivative of Brefeldin A (HY-16592), is a EGFR modulator. CHNQD-01281 has strong antiproliferative activities against cancer cells (IC50: 0.079 and 0.081 μM for T24 and J82 cells, respectively). CHNQD-01281 regulates both EGFR/PI3K/AKT and EGFR/ERK pathways and mediates the chemotactic effect of chemokines on immune effector cells. CHNQD-01281 remarkably inhibits tumor growth in T24 xenograft mice model and prolongs the survival time in MB49 allogeneic mice model via inducing infiltration of cytotoxic T cells.
    CHNQD-01281
  • HY-W612557
    Edaravone dimer impurity
    Edaravone dimer impurity (Dimer 2) is a stable conjugated Edaravone (HY-B0099) dimer. Edaravone is a free radical scavenging agent for the study of acute ischemic stroke.
    Edaravone dimer impurity
  • HY-149683
    WAY-639228
    		≥98.0%
    WAY-639228-A is an active molecule.
    WAY-639228
  • HY-129953C
    5-trans Prostaglandin F2α tromethamine
    5-trans Prostaglandin F2α tromethamine is a derivative of 5-trans Prostaglandin F2α (HY-129953A). 5-trans Prostaglandin F2α is an endogenous metabolite present in blood that can be used for the research of myocardial infarction.
    5-trans Prostaglandin F2α tromethamine