2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. Sodium Channel
  5. Sodium Channel Antagonist

Sodium Channel Antagonist

Sodium Channel Isoform Comparison

Sodium Channel Antagonists (24):

Cat. No. Product Name Effect Purity
  • HY-123825
    GX-674
    		Antagonist
    GX-674 is a potent, state-dependent, isoform-selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50 of 0.1 nM at -40 mV.
  • HY-W803860
    N-Depropylpropafenone
    		Antagonist
    N-Depropylpropafenone is an active metabolite of Propafenone (HY-B0432), generated through the CYP450 enzyme system (mainly CYP2D6). It functions by blocking sodium ion channels, slowing myocardial conduction and exhibiting certain antiarrhythmic effects.
  • HY-107186
    EO-122
    		Antagonist
    EO-122 is a potent antagonist of calcium channel and sodium channel potentially for the research of arrhythmia.
  • HY-A0082S
    Diphenidol-d10 hydrochloride
    		Antagonist
    Diphenidol-d10 (hydrochloride) (Difenidol hydrochloride-d10) is deuterium labeled Diphenidol (hydrochloride). Diphenidol hydrochloride (Difenidol hydrochloride) is a non-selective muscarinic M1-M4 receptor antagonist, has anti-arrhythmic activity. Diphenidol hydrochloride is also a potent non-specific blocker of voltage-gated ion channels (Na+, K+, and Ca2+) in neuronal cells. Diphenidol hydrochloride can be used in the study of antivertigo and antinausea.