1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-130431
    Vinclozolin M2
    Vinclozolin M2 is an active metabolite of vinclozolin. It is formed from vinclozolin by successive esterase activity and decarboxylation of vinclozolin in C. elegans and by decarboxylation in human liver microsomes. Vinclozolin M2 is an antagonist of the mineralocorticoid receptor (IC50=1,400 nM) and androgen receptor (IC50=0.17 nM) in reporter assays using MCF-7 cells.
    Vinclozolin M2
  • HY-66035
    4-(Trifluoromethyl)nicotinic acid
    Control 98.24%
    4-(Trifluoromethyl)nicotinic acid (4-(Trifluoromethyl)pyridine-3-carboxylic acid) is a metabolite of the pyridinecarboxamide insecticide Flonicamid (HY-119649).
    4-(Trifluoromethyl)nicotinic acid
  • HY-124485
    Nitroscanate
    Nitroscanate is an anthelmintic that has a calming effect on animals.
    Nitroscanate
  • HY-121200
    Azadirone
    Inhibitor
    Azadirone sensitized cancer cells to TNF-related apoptosis-inducing ligand (TRAIL) through ROS-ERK-CHOP-mediated up-regulation of DR5 and DR4 expression, down-regulation of cell survival proteins, and up-regulation of proapoptotic proteins (Bid). Azadirone has antiplasmodial activity.
    Azadirone
  • HY-12610
    Carbonic anhydrase inhibitor 27
    Inhibitor
    Carbonic anhydrase inhibitor 27 (compund 5g) is an antitrypanosomal agent that reduces parasites in the bloodstream and improves survival of infected mice.
    Carbonic anhydrase inhibitor 27
  • HY-N14053
    Arohynapene A
    Inhibitor
    Arohynapene A is an anticoccidial compound that inhibits the growth of Eimeria tenella.
    Arohynapene A
  • HY-12641R
    Pyrantel (tartrate) (Standard)
    Inhibitor
    Pyrantel (tartrate) (Standard) is the analytical standard of Pyrantel (tartrate). This product is intended for research and analytical applications. Pyrantel tartrate is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel tartrate can cause spasmodic muscle paralysis in parasites. Pyrantel tartrate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis.
    Pyrantel (tartrate) (Standard)
  • HY-173356
    Antiparasitic agent-26
    Inhibitor
    Antiparasitic agent-26 (Compound 8) is an antiparasitic compound that potently inhibits the growth of Naegleria fowleri, with IC50 values of 22.87 μM (trophozoite stage) and 25.16 μM (cyst stage). Antiparasitic agent-26 exerts its antiparasitic activity by inducing programmed cell death, including cytoplasmic calcium accumulation, mitochondrial membrane potential collapse, ATP synthesis inhibition, ROS accumulation, and chromatin condensation. Antiparasitic agent-26 can be used in the research of primary amoebic meningoencephalitis (PAM).
    Antiparasitic agent-26
  • HY-N14197
    Hynapene B
    Inhibitor
    Hynapene A inhibits Eimeria tenella with a MIC of 34.7 μM.
    Hynapene B
  • HY-117375
    Brotianide
    Inhibitor
    Brotianide is a potent anti-parasitic agent. Brotianide can be used to study liver fluke and gastric fluke infestations.
    Brotianide
  • HY-B0486R
    Lonidamine (Standard)
    Lonidamine (Standard) is the analytical standard of Lonidamine. This product is intended for research and analytical applications. Lonidamine (AF-1890) is a hexokinase and mitochondrial pyruvate carrier inhibitor (Ki: 2.5 μM). Lonidamine also inhibits aerobic glycolysis in cancer cells. Lonidamine can be used in the research of mitochondrial metabolism and inflammation, such as pulmonary fibrosis.
    Lonidamine (Standard)
  • HY-A0148AR
    Halofantrine (hydrochloride) (Standard)
    Inhibitor
    Halofantrine (hydrochloride) (Standard) is the analytical standard of Halofantrine (hydrochloride). This product is intended for research and analytical applications. Halofantrine hydrochloride (SKF-102886) is a blocker of delayed rectifier potassium current via the inhibition of human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial compound.
    Halofantrine (hydrochloride) (Standard)
  • HY-13834
    GW844520
    Inhibitor
    GW844520 is an orally active inhibitor of cytochrome bc1 complex. GW844520 can be used in malaria and anti-plasmodium related research.
    GW844520
  • HY-N2927
    Costic acid
    Inhibitor
    Costic acid (β-Costic acid) is a natural product, that can be isolated from Dittrichia viscosa. Costic acid exhibits potent in vivo acaricidal activity against the parasite. Costic acid is not toxic for human umbilical vein endothelial cells (HUVEC) at concentrations of up to 230 μM. Costic acid can be used for the research of varroosis in honey bee colonies.
    Costic acid
  • HY-N7141R
    Spiramycin I (Standard)
    Inhibitor
    Spiramycin I (Standard) is the analytical standard of Spiramycin I. This product is intended for research and analytical applications. Spiramycin I is a macrolide antibiotic and antiparasitic.
    Spiramycin I (Standard)
  • HY-N14309
    Astechrome
    Inhibitor
    Astechrome is a natural product with a strong antimalarial activity with an IC50 value of 0.94 μM. Astechrome exhibits cytotoxicity against Vero cells with IC50 value of 7.9 μM.
    Astechrome
  • HY-12638R
    Dichlorophen (Standard)
    Inhibitor
    Dichlorophen (Standard) is the analytical standard of Dichlorophen. This product is intended for research and analytical applications. Dichlorophen (DDM) is an anticestodal agent. Dichlorophen is an antimicrobial agent shown to exert activity against cestodes, protozoa, fungi, and bacteria.
    Dichlorophen (Standard)
  • HY-B1207R
    Urethane (Standard)
    Inhibitor
    Urethane (Standard) is the analytical standard of Urethane. This product is intended for research and analytical applications. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro.
    Urethane (Standard)
  • HY-134013
    Piperitenone oxide
    Inhibitor
    Piperitenone oxide (lippione), a monoterpene, can be isolated from the n-hexane extract from spearmint (Mentha spicata) leaves. Piperitenone oxide is a potent inducer of differentiation in a RCM-1 human colon cancer cell line.
    Piperitenone oxide
  • HY-118769
    Japonilure
    Japonilure serves as an agent for insecticides and pheromones.
    Japonilure

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