2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-116757
    (±)-α-CMBHC
    (±)-α-CMBHC is a metabolite of α-Tocopherol.
    (±)-α-CMBHC
  • HY-B1827A
    D-Galacturonic acid
    D-Galacturonic acid (D-galUA) is a sugar acid, which is found in pectin.
    D-Galacturonic acid
  • HY-156787
    Porfimer sodium
    Porfimer sodium (Photofrin II) is a photosensitizing compound used primarily for photodynamic inhibition. Porfimer sodium is selectively taken up by tumor cells and can generate oxygen free radicals upon activation. Porfimer sodium causes changes in Ca(2+) concentrations within cells, exhibiting acute electrophysiological responses and changes in cell morphology. The application of porfimer sodium can lead to the formation of micropores on the cell membrane surface, resulting in necrotic cell death.
    Porfimer sodium
  • HY-N0529R
    Rosmarinic acid (Standard)
    Rosmarinic acid (Standard) is the analytical standard of Rosmarinic acid. This product is intended for research and analytical applications. Rosmarinic acid is a widespread phenolic ester compound in the plants. Rosmarinic acid inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively.
    Rosmarinic acid (Standard)
  • HY-Y0624R
    4-Pentenoic acid (Standard)
    4-Pentenoic acid (Standard) is the analytical standard of 4-Pentenoic acid (HY-Y0624). This product is intended for research and analytical applications. 4-Pentenoic acid is a medium-chain unsaturated fatty acid. 4-Pentenoic acid has hypoglycemic and fatty acid oxidation inhibitory activities. 4-Pentenoic acid can affect blood glucose metabolism and energy metabolism through mechanisms such as inhibiting long-chain fatty acid oxidation, reducing gluconeogenesis, and promoting glucose utilization.
    4-Pentenoic acid (Standard)
  • HY-17463S
    Prednisolone-d8
    Prednisolone-d8 is the deuterium labeled Prednisolone. Prednisolone is a potent, orally active corticosteroid and a glucocorticoid. Prednisolone possesses about four times the anti-inflammatory activity of hydrocortisone while causing less salt and water retention. Prednisolone can be used for ocular, anti-inflammatory research[1][2].
    Prednisolone-d<sub>8</sub>
  • HY-P3964
    TRH Precursor Peptide
    TRH Precursor Peptide is a precursor peptide of thyrotropin-releasing hormone (TRH). TRH Precursor Peptide formation of TRH in rat brain and pituitary is zinc-dependent.
    TRH Precursor Peptide
  • HY-P10616
    Salusin-α
    Salusin-α is an endogenous bioactive peptide with hemodynamic and cell proliferation activities. Salusin-α can stimulate the proliferation of quiescent vascular smooth muscle cells (VSMCs) and fibroblasts, leading to a rapid and significant decrease in blood pressure and heart rate, but its effect is weaker than that of Salusin-β (HY-P10617). Salusin-α has potential application value in cardiovascular disease research.
    Salusin-α
  • HY-N1446AR
    Glycerol Monoleate (Standard)
    Glycerol Monoleate (Standard) is the analytical standard of Glycerol Monoleate. This product is intended for research and analytical applications. Glycerol Monoleate is a nontoxic, biodegradable and biocompatible, lipophilic glycerol fatty acid ester. Glycerol monooleate has hemolytic properties. glycerol monooleate is used as an emulsifier and an absorption enhancer in combination with bile salts. Glycerol Monoleate can be used in drug delivery systems and siRNA delivery in Vitro.
    Glycerol Monoleate (Standard)
  • HY-N8355
    Beauveriolide I
    Beauveriolide I is the metabolite of Entomopathogenic Fungi Beauveria sp.. Beauveriolide I (1) exhibits moderate insecticidal activities against Spodoptera litura and Callosobruchus chinensis.
    Beauveriolide I
  • HY-113113
    13,14-Dihydro PGE1
    13,14-Dihydro PGE1 is a metabolite of PGE1 (Prostaglandin E1) which inhibits the ADP-induced platelet aggregation (ID50 = 10.8 ng/mL platelet rich plasma).
    13,14-Dihydro PGE1
  • HY-W040240R
    (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one (Standard)
    (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one (Standard) is the analytical standard of (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. This product is intended for research and analytical applications. (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite.
    (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one (Standard)
  • HY-B1449S6
    Uridine-d
    Uridine-d is the deuterium labeled Uridine.[1].
    Uridine-d
  • HY-W010066R
    4-(1,2-Dihydroxyethyl)benzene-1,2-diol (Standard)
    Scopolamine (hydrobromide trihydrate) (Standard) is the analytical standard of Scopolamine (hydrobromide trihydrate). This product is intended for research and analytical applications. Scopolamine hydrobromide trihydrate (Hyoscine hydrobromide trihydrate) is used in ophthalmic preparations and has the potential for transdermal patches of motion sickness.
    4-(1,2-Dihydroxyethyl)benzene-1,2-diol (Standard)
  • HY-I1060S
    L-Alloisoleucine-d10
    L-Alloisoleucine-d10 is the deuterium labeled L-Alloisoleucine. L-Alloisoleucine is a branched chain amino acid and is a stereo-isomer of L-isoleucine. L-Alloisoleucine is a common constituent of human plasma (albeit at low levels).
    L-Alloisoleucine-d<sub>10</sub>
  • HY-N2334AR
    Glycochenodeoxycholic acid sodium salt (Standard)
    Glycochenodeoxycholic acid sodium salt (Standard) is the analytical standard of Glycochenodeoxycholic acid sodium salt. This product is intended for research and analytical applications. Glycochenodeoxycholic acid sodium salt (Sodium glycochenodeoxycholate) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid sodium salt inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the Apoptosis of human hepatocyte cells. Glycochenodeoxycholic acid sodium salt induces stemness and chemoresistance via activating STAT3 signaling pathway in hepatocellular carcinoma cells (HCC). Glycochenodeoxycholic acid sodium salt is promising for research in the field of cholestasis desease, hepatocellular carcinoma and primary sclerosing cholangitis (PSC).
    Glycochenodeoxycholic acid sodium salt (Standard)
  • HY-W747583
    Apocholic acid
    Apocholic acid, a Bile acid, is an endogenous metabolite.
    Apocholic acid
  • HY-W585865
    UDP-3-O-acyl-GlcNAc Tris
    UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine) Tris is an E. coli metabolite that is involved in 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway.
    UDP-3-O-acyl-GlcNAc Tris
  • HY-113273C
    Diadenosine pentaphosphate pentalithium
    Diadenosine pentaphosphate pentalithium is an endogenous vasoactive purine dinucleotide which has been isolated from thrombocytes. Diadenosine polyphosphates (ApnA, n=2–7) have been identified as constituents of secretory vesicles such as in platelets, chromaffin cells, Torpedo synaptic terminals and brain synaptosomes.
    Diadenosine pentaphosphate pentalithium
  • HY-B2219S1
    Stearic acid-d2
    Stearic acid-d2 is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.
    Stearic acid-d<sub>2</sub>
Cat. No. Product Name / Synonyms Application Reactivity