2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-113320R
    Etiocholanolone (Standard)
    Cimbuterol (Standard) is the analytical standard of Cimbuterol. This product is intended for research and analytical applications. Cimbuterol is a β-adrenergic receptor agonist.
    Etiocholanolone (Standard)
  • HY-P2888A
    Bilirubin oxidase, bacillus cereus
    Bilirubin oxidase, bacillus cereus is a multi-copper oxidase that catalyzes the oxidation of bilirubin into biliverdin, as well as other tetrapyrroles, phenols, and aryl diamines. Bilirubin oxidase, bacillus cereus can serve as a single-enzyme deoxygenator, catalyzing the direct reduction of oxygen to water in the presence of electron donor substrates, without releasing hydrogen peroxide. Bilirubin oxidase, bacillus cereus can be used to develop enzyme-based biosensors.
    Bilirubin oxidase, bacillus cereus
  • HY-E70251
    22:6 Coenzyme A
    22:6 Coenzyme A (Docosahexaenoyl coenzyme A triammonium) is a coenzyme that contains 22 carbon atoms and 6 unsaturated bonds. 22:6 Coenzyme A can serve as an acyl substrate and is used in research on the effects of lysophospholipid acyltransferase activities in adipocyte differentiation.
    22:6 Coenzyme A
  • HY-W010388S
    Creatine-13C
    Creatine-13C is the 13C labeled Creatine[1]. Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain[2].
    Creatine-<sup>13</sup>C
  • HY-Y1667S
    2,6-Dibromophenol-d3
    2,6-Dibromophenol-d3 is the deuterium labeled 2,6-Dibromophenol[1]. 2,6-Dibromophenol is an endogenous metabolite.
    2,6-Dibromophenol-d<sub>3</sub>
  • HY-113037
    (E/Z)-Farnesyl pyrophosphate
    (E/Z)-Farnesyl pyrophosphate ((E/Z)-Farnesyl diphosphate), a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway. (E/Z)-Farnesyl pyrophosphate is a TRPM2 (TRP Channel) agonist, activates TRPM2 opening for ion influx. (E/Z)-Farnesyl pyrophosphate is a key branch substrate for cholesterol synthesis, ubiquinones synthesis, protein farnesylation decoration, and geranyl-geranyl pyrophosphate (GGPP) synthesis.
    (E/Z)-Farnesyl pyrophosphate
  • HY-129953S
    9α,11β-Prostaglandin F2α-d4
    9α,11β-Prostaglandin F2α-d4 is a deuterated labeled 9α,11β-Prostaglandin F2α. 9α,11β-Prostaglandin F2α is an endogenous metabolite present in Urine that can be used for the research of Asthma.
    9α,11β-Prostaglandin F2α-d<sub>4</sub>
  • HY-N0437S1
    Progesterone-13C5
    Progesterone-13C5 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
    Progesterone-<sup>13</sup>C<sub>5</sub>
  • HY-N0379S2
    D-Mannose-18O
    D-Mannose-18O is the 18O labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote[1][2].
    D-Mannose-<sup>18</sup>O
  • HY-W008841S1
    N-Methylformamide-d5
    N-Methylformamide-d5 is the deuterium labeled N-Methylformamide[1].
    N-Methylformamide-d<sub>5</sub>
  • HY-115433S1
    α-Muricholic acid-d4
    α-Muricholic acid-d4 is the deuterium labeled α-Muricholic acid. α-Muricholic acid is the most abundant primary bile acid in rodents[1][2].
    α-Muricholic acid-d<sub>4</sub>
  • HY-W004305R
    Hexadecanal (Standard)
    Hexadecanal (Standard) is an analytical standard for Hexadecanal. This product is intended for research and analytical applications. Hexadecanal (Palmitaldehyde), a volatile, long-chain fatty aldehyde, is released from human feces, skin, and breath. The hexadecanal receptor (OR37B) is highly conserved in mammals. Hexadecanal may exert its effects by modulating functional connectivity between social evaluation brain substrates and aggression execution brain substrates. Hexadecanal has also been shown to have a strong deterrent effect on black ants. Hexadecanal has potential for use in startle response and aggression behavior
    Hexadecanal (Standard)
  • HY-N0059S3
    D-Arabinose-13C-3
    D-Arabinose-13C-3 is the 13C labeled D-arabinose. D-arabinose is an endogenous metabolite[1].
    D-Arabinose-<sup>13</sup>C-3
  • HY-W012836S1
    4-Ethylphenol-d10
    4-Ethylphenol-d10 is the deuterium labeled 4-Ethylphenol[1]. 4-Ethylphenol is a volatile phenolic compound associated with off-odour in wine[2].
    4-Ethylphenol-d<sub>10</sub>
  • HY-130441
    Leukotriene B3
    Leukotriene B3 is a LTA hydrolase metabolite of LTA3 in the leukotriene biosynthesis pathway. Leukotriene B3 has proinflammatory activity.
    Leukotriene B3
  • HY-P10720
    C-Type Natriuretic Peptide (1-53), Porcine, Rat,mouse
    C-Type Natriuretic Peptide (1-53), Porcine, Rat, mouse is an activator of particulate guanylate cyclase B (pGC-B), which is highly expressed in endothelial cells, kidneys, and the heart. C-Type Natriuretic Peptide (1-53), Porcine, Rat, mouse can mediate a potent anti-fibrotic effect in human cardiac and renal fibroblasts by generating the second messenger cGMP.
    C-Type Natriuretic Peptide (1-53), Porcine, Rat,mouse
  • HY-W014423S2
    L-Histidine-13C6 hydrochloride hydrate
    L-Histidine-13C6 (hydrochloride hydrate) is the 13C-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
    L-Histidine-<sup>13</sup>C<sub>6</sub> hydrochloride hydrate
  • HY-10585S3
    Valproic acid-d4 sodium
    Valproic acid-d4 (sodium) is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.
    Valproic acid-d<sub>4</sub> sodium
  • HY-128965R
    N-Glycolylneuraminic acid (Standard)
    N-Glycolylneuraminic acid (Standard) is the analytical standard of N-Glycolylneuraminic acid. This product is intended for research and analytical applications. N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs).
    N-Glycolylneuraminic acid (Standard)
  • HY-N6725R
    Sterigmatocystine (Standard)
    Sterigmatocystine (Standard) is the analytical standard of Sterigmatocystine. This product is intended for research and analytical applications. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor. Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals.
    Sterigmatocystine (Standard)
Cat. No. Product Name / Synonyms Application Reactivity