2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-P2984
    Adenosine triphosphatase
    Adenosine triphosphatase is an enzyme that catalyzes the decomposition of ATP into ADP and a free phosphate ion (Pi).
    Adenosine triphosphatase
  • HY-131395
    N-Acetyl-Leukotriene E4
    N-Acetyl-Leukotriene E4 (N-Acetyl-LTE4) is a metabolite of Leukotriene E4 (LTE4) (HY-113465), which is detected in bile and urine. N-Acetyl-Leukotriene E4 produces a vasoconstriction in the mesenteric vessels which led to reduction of blood flow to the gut.
    N-Acetyl-Leukotriene E4
  • HY-126230A
    (Rac)-PAT-494
    (Rac)-PAT-494 is a type II autotaxin inhibitor with the activity of inhibiting the production of lysophosphatidic acid (LPA) in the blood. (Rac)-PAT-494 can participate in the inhibition of diseases related to cancer, fibrosis and inflammation by antagonizing the function of autotaxin. (Rac)-PAT-494 shows high activity in biochemical and plasma tests. (Rac)-PAT-494 can reduce plasma LPA levels after oral administration to rats.
    (Rac)-PAT-494
  • HY-W034065
    3,5-Dihydroxyacetophenone
    		99.96%
    3,5-Dihydroxyacetophenone is an endogenous metabolite.
    3,5-Dihydroxyacetophenone
  • HY-165108
    1,2-Dilinoleoyl-3-α-linolenoyl-rac-glycerol
    1,2-Dilinoleoyl-3-α-linolenoyl-rac-glycerol (1,2-Linolein-3-α-linolenin) is a compound used in the study of triglyceride composition of vegetable oils. It was analyzed by supercritical CO? chromatography-mass spectrometry to determine its content and characteristics in different vegetable oils.
    1,2-Dilinoleoyl-3-α-linolenoyl-rac-glycerol
  • HY-113446R
    Leukotriene C4 (Standard)
    Leukotriene C4 (Standard) is the analytical standard of Leukotriene C4. This product is intended for research and analytical applications. Leukotriene C4 is a eicosanoid lipid mediator and produced by immune cells during type 2 inflammation. Leukotriene C4 can mediate inflammation,allergy, bronchoconstriction, and vascular leakage.
    Leukotriene C4 (Standard)
  • HY-B0400S3
    D-Sorbitol-13C-2
    D-Sorbitol-13C-2 is the 13C labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary
    D-Sorbitol-<sup>13</sup>C-2
  • HY-113025A
    L-hydroxylysine dihydrochloride
    L-hydroxylysine dihydrochloride ((2S,5R)-5-Hydroxylysine dihydrochloride), an amino acid, is exclusive to collagen protein, which is formed by posttranslational hydroxylation of some lysine residues.
    L-hydroxylysine dihydrochloride
  • HY-W015410S2
    Disodium succinate-d4
    Disodium succinate-d4 is the deuterium labeled Disodium succinate[1]. Disodium succinate is the disodium salt of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism[2].
    Disodium succinate-d<sub>4</sub>
  • HY-N0210S8
    D-Galactose-d-3
    D-Galactose-d-3 is the deuterium labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose.
    D-Galactose-d-3
  • HY-E70417
    Glycerol-3-phosphate dehydrogenase, Saccharomyces cerevisiae
    Glycerol-3-phosphate dehydrogenase, Saccharomyces cerevisiae, is an enzyme involved in glycerol metabolism and energy production, responsible for catalyzing the oxidation of glycerol-3-phosphate (G3P) to dihydroxyacetone phosphate (DHAP). Glycerol-3-phosphate dehydrogenase, Saccharomyces cerevisiae, is the rate-limiting enzyme in glycerol production in Saccharomyces cerevisiae, and helps Saccharomyces cerevisiae adapt to high osmotic environments by regulating glycerol production and accumulation. Glycerol-3-phosphate dehydrogenase, Saccharomyces cerevisiae, can be used in research within the field of metabolic engineering.
    Glycerol-3-phosphate dehydrogenase, Saccharomyces cerevisiae
  • HY-N0771S8
    L-Isoleucine-d
    L-Isoleucine-d is the deuterium labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid.
    L-Isoleucine-d
  • HY-B1897AR
    Menadione bisulfite (sodium) (Standard)
    Menadione bisulfite (sodium) (Standard) is the analytical standard of Menadione bisulfite (sodium). This product is intended for research and analytical applications. Menadione bisulfite (sodium) is used as an agent to induce acute oxidative stress, and to function as a plant-defense activator against several pathogens.
    Menadione bisulfite (sodium) (Standard)
  • HY-131605
    Ganciclovir triphosphate
    Ganciclovir triphosphate (GCV-TP) is a synthetic 2'-deoxyguanosine analog with activity in inhibiting human cytomegalovirus (CMV) replication. Ganciclovir triphosphate is effective against CMV infection by binding to viral DNA polymerase and interfering with viral DNA synthesis. Ganciclovir triphosphate has an IC50 of 0.01 μM and has good antiviral effects against CMV strains from humans, monkeys, mice, and guinea pigs. Ganciclovir triphosphate has also been used in gene-directed enzyme prodrug inhibition for cancer inhibition.
    Ganciclovir triphosphate
  • HY-N4075R
    O-Desmethylangolensin (Standard)
    20(R)-Ginsenoside Rh2 (Standard) is the analytical standard of 20(R)-Ginsenoside Rh2. This product is intended for research and analytical applications. 20(R)-Ginsenoside Rh2, a matrix metalloproteinase (MMP) inhibitor, acts as a cell antiproliferator. It has anticancer effects via blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis, and has anti-inflammatory and antioxidative activity. 20(R)-Ginsenoside Rh2 inhibits the replication and proliferation of mouse and human gammaherpesvirus 68 (MHV-68) with an IC50 of 2.77 μM for murine MHV-68.
    O-Desmethylangolensin (Standard)
  • HY-B0471S3
    Phenylephrine-d6 hydrochloride
    Phenylephrine-d6 (hydrochloride) is deuterium labeled Phenylephrine (hydrochloride). (R)-(-)-Phenylephrine hydrochloride is a selective α1-adrenoceptor agonist with pKis of 5.86, 4.87 and 4.70 for α1D, α1B and α1A receptors respectively.
    Phenylephrine-d<sub>6</sub> hydrochloride
  • HY-125731R
    Glycodeoxycholic Acid (Standard)
    Glycodeoxycholic Acid (Standard) is the analytical standard of Glycodeoxycholic Acid. This product is intended for research and analytical applications. Glycodeoxycholic Acid is a natural product found in Streptomyces nigricans, Trypanosoma brucei and C. elegans. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis.
    Glycodeoxycholic Acid (Standard)
  • HY-N0420A
    Succinic acid tromethamine
    Succinic acid tromethamine is a potent and orally active anxiolytic agent. Succinic acid tromethamine is an intermediate product of the tricarboxylic acid cycle. Succinic acid tromethamine can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries.
    Succinic acid tromethamine
  • HY-P1940R
    Maculosin (Standard)
    Complanatuside (Standard) is the analytical standard of Complanatuside. This product is intended for research and analytical applications. Complanatuside is a flavonoid found in the traditional Chinese medicine Semen Astragali Complanati.
    Maculosin (Standard)
  • HY-41121S1
    Boc-L-Ala-OH-3-13C
    Boc-L-Ala-OH-3-13C is a 13C-labeled Hypoxanthine. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
    Boc-L-Ala-OH-3-<sup>13</sup>C
Cat. No. Product Name / Synonyms Application Reactivity