2. Signaling Pathways
  3. Cell Cycle/DNA Damage
    Cytoskeleton
  4. Kinesin
  5. Kinesin Isoform

Kinesin

 

Kinesin Related Products (58):

Cat. No. Product Name Effect Purity
  • HY-158757
    KIF18A-IN-12
    		Inhibitor
    KIF18A-IN-12 (compound 9) is a KIF18A inhibitor, with an IC50 value of 45.54 nM. KIF18A-IN-12 can be used in cancer research.
  • HY-162532
    KIF18A-IN-10
    		Inhibitor
    KIF18A-IN-10 (Compound 24) is a potent KIF18A inhibitor, with an IC50 value of 23.8 nM. KIF18A-IN-10 has anticancer activity, with IC50 values of less than 100 nM in OVCAR3 and MDA-MB-157 cells.
  • HY-124790
    KSP-IA
    		Inhibitor
    KSP-IA (compound 17) is a potent kinesin spindle protein (KSP) inhibitor with an IC50 value of 3.6 nM. KSP-IA inhibits cell mitosis.
  • HY-RS07292
    KIF6 Human Pre-designed siRNA Set A
    		Inhibitor

    KIF6 Human Pre-designed siRNA Set A contains three designed siRNAs for KIF6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-150265
    TNH
    		Activator
    TNH (TMP-NVOC linker-Halo) is a dimeric protein chemical inducer that can enter living cells and recruit proteins to cellular structures. TNH senses light signals and acts by recruiting proteins to kinetochores and releasing them from kinetochores (depending on CENP-E (kinesin-7)).
  • HY-RS07293
    Kif6 Mouse Pre-designed siRNA Set A
    		Inhibitor

    Kif6 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kif6 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-164979
    KIF18A-IN-15
    		Inhibitor
    KIF18A-IN-15 (Compound Example 36) is a KIF18A inhibitor, available in two forms, EX36-A and its enantiomer EX36-B, with IC50s of 0.01-0.1 μM, respectively. EX36-A and EX36-B inhibit OVCAR-3 cells viability with IC50s of 0.01-0.1 μM and 0-0.01 μM, respectively. KIF18A-IN-15 can be used in tumor (e.g. colon, breast, lung) studies.
  • HY-162531
    KIF18A-IN-9
    		Inhibitor
    KIF18A-IN-9 (Compound 1) is a potent KIF18A inhibitor, with an IC50 value of 3.8 nM. KIF18A-IN-9 has anticancer activity, with IC50 values of less than 100 nM in OVCAR3 and MDA-MB-157 cells.
  • HY-168727
    KSP ligand 1
    KSP ligand 1 is a protein ligand that targets KSP (Kinesin), and it can be used to synthesize PROTAC KSP-IN-1 (HY-168725) for cancer research.
  • HY-162518
    Eg5-IN-3
    		Inhibitor
    Eg5-IN-3 (5) is an Eg5 inhibitor that targets the novel allosteric pocket (α4/α6/L11). Eg5-IN-3 (5) causes tubulin assembly distortion with irregular morphology, resulting in a typical mitotic arrest similar to Monastrol (HY-101071A).
  • HY-RS07261
    KIF14 Human Pre-designed siRNA Set A
    		Inhibitor

    KIF14 Human Pre-designed siRNA Set A contains three designed siRNAs for KIF14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-164980
    KIF18A-IN-16
    		Inhibitor
    KIF18A-IN-16 (Compound 15) is a fused ring KIF18A inhibitor. KIF18A-IN-16 can be used in oncology (e.g., colon, breast, lung cancer) studies.
  • HY-10084
    CK0106023
    		Inhibitor
    CK0106023 is a potent and specific allosteric inhibitor of KSP with a Ki value of 12 nM, showing antitumor activity. CK0106023 causes mitotic arrest and growth inhibition in several tumor cell lines. CK0106023 exhibits antitumor activity in tumor-bearing mice.
  • HY-50759S
    Ispinesib-d5
    		Inhibitor
    Ispinesib-d5 (SB-715992-d5) is a deuterium labeled Ispinesib (HY-50759). Ispinesib is a specific inhibitor of kinesin spindle protein (KSP).
  • HY-117440
    4'-Methoxy-S-trityl-L-cysteinol
    		Inhibitor
    4'-Methoxy-S-trityl-L-cysteinol is an allosteric inhibitor of vertebrate Kinesin Spindle Protein (KSP). 4'-Methoxy-S-trityl-L-cysteinol significantly enhances its inhibitory activity against NCI60 tumor cells by modifying the trityl and cysteine groups. Its EC50 for bipolar spindle formation is 28 μM, showing stronger inhibitory potency than the parent molecule and monastrol.
  • HY-124823
    Monastroline
    		Inhibitor
    Monastroline (HR22C16) is an effective and selective inhibitor of the mitotic kinesin Eg5, exhibiting strong cell permeability.
  • HY-157338
    NHS-Ala-Ala-Asn-active metabolite
    		Inhibitor
    NHS-Ala-Ala-Asn-active metabolite is a cleavable antibody-drug conjugate (ADC) linker for synthesis of kinesin spindle protein (KSP)inhibitor.
  • HY-110090
    UA62784
    		Inhibitor
    UA62784 is a microtubule polymerization inhibitor that interacts with tubulin dimers. UA62784 is a novel specific inhibitor of centromere protein E (CENP-E) kinesin. UA62784 can be used for the study of pancreatic cancer.