2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. Dopamine Receptor
  5. Dopamine Receptor Isoform
  6. Dopamine Receptor Agonist

Dopamine Receptor Agonist

Dopamine Receptor Agonists (109):

Cat. No. Product Name Effect Purity
  • HY-B0735AR
    Fenoldopam (mesylate) (Standard)
    		Agonist
    Fenoldopam (mesylate) (Standard) is the analytical standard of Fenoldopam (mesylate). This product is intended for research and analytical applications. Fenoldopam mesylate (SKF-82526) is a D1 receptor agonist and a novel lysine-specific demethylase 1 (LSD1) inhibitor (IC50=0.8974 μM). Fenoldopam mesylate shows anti-hypertensive effects, anti-cancer cell proliferation activity and can induce cells apoptosis.
  • HY-A0172
    Captodiame
    		Agonist
    Captodiame (Captodiamine) is a 5-HT2c receptor antagonist and sigma-1 and D3 dopamine receptor agonist. Captodiame shows antidepressant effect.
  • HY-123440
    S3608
    		Agonist
    S3608 is an atypical dopamine agonist. S3608 dose dependently increase locomotor activity (LA) in rats.
  • HY-15238
    ST-836
    		Agonist
    ST-836 is a dopamine receptor ligand; Antiparkinsonian agent.
  • HY-109112R
    Brilaroxazine (Standard)
    		Agonist
    Brilaroxazine (Standard) is the analytical standard of Brilaroxazine. This product is intended for research and analytical applications. Brilaroxazine (RP5603) is a potent and orally active multimodal dopamine (DA)/serotonin (5-HT) modulator. Brilaroxazine is a partial agonist of dopamine (DA) D2, D3, and D4 receptors, 5-HT1A (Ki=1.5 nM) and 5-HT2A (Ki=2.5 nM), and has antagonist activity at 5-HT2B (Ki=0.19 nM), and 5-HT7 (Ki=2.7 nM) receptors. Brilaroxazine is an atypical antipsychotic agent, and has the potential to improve cognitive impairments in neuropsychiatric and neurological diseases in vivo.
  • HY-106100AR
    Roxindole hydrochloride (Standard)
    		Agonist
    Roxindole (hydrochloride) (Standard) is the analytical standard of Roxindole (hydrochloride). This product is intended for research and analytical applications. Roxindole hydrochloride (EMD 38362), an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors, with an affinity for the D2-like subtype in the low nanomolar range. Roxindole can be used for the research of positive and negative schizophrenic symptoms. Roxindole is a 5-HT1A agonist and 5-HT uptake inhibitor with high affinity for 5-HT1A (IC50=0.9 nM). Antipsychotic and antidepressant activities.
  • HY-A0040
    Talipexole
    		Agonist
    Talipexole (B-HT920) is a dopamine agonist that has been proposed as an antiparkinsonian agent.
  • HY-U00400
    PF-592379
    		Agonist
    PF-592379 is a potent dopamine D3 receptor agonist with an EC50 of 21 nM.
  • HY-U00227
    U91356
    		Agonist
    U91356 is a dopamine receptor agonist.