2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
    Neuronal Signaling
  4. Calcium Channel
  5. T-type calcium channel Isoform
  6. T-type calcium channel Inhibitor

T-type calcium channel Inhibitor

T-type calcium channel Inhibitors (24):

Cat. No. Product Name Effect Purity
  • HY-147639
    Cav 2.2/3.2 blocker 1
    		Inhibitor
    Cav 2.2/3.2 blocker 1 (Compound 9e) is a neuronal calcium channel blocker with IC50 values of 78 μM and 80 μM against Cav2.2 and Cav3.2, respectively. Cav 2.2/3.2 blocker 1 can penetrate the CNS.
  • HY-151452
    Cav 3.2 inhibitor 3
    		Inhibitor
    Cav 3.2 inhibitor 3 (Compound 4) is a potent Cav3.2 T-type Ca2+ channel inhibitor with an IC50 of 0.1534 μM, and has little binding affinity to D2 receptors.
  • HY-147708
    T-Type calcium channel inhibitor 2
    		Inhibitor
    T-Type calcium channel inhibitor 2 (compound 6g) is a potent T-type calcium channel inhibitor with IC50s of 31.0, 83.1, 69.3 µM for Cav3.1 (α1G), Cav3.2 (α1H), Cav3.3 (α1I) (α1H), respectively. T-Type calcium channel inhibitor 2 shows cytotoxicity for A549, HCT-116 cells with IC50s of 5.0, 6.4 µM, respectively.
  • HY-101616
    ABT-639 hydrochloride
    		Inhibitor
    ABT-639 hydrochloride is a novel, peripherally acting, selective T-type Ca2+ channel blocker.