CXCR Inhibitor

CXCR Inhibitors (39):

Cat. No.	Product Name	Effect	Purity

HY-149558

CXCR4-IN-2	Inhibitor
CXCR4-IN-2 (compound A1) is a bifunctional fluorinated small molecule that is a potent CXCR4 inhibitor with anticancer activity. CXCR4-IN-2 has cytotoxic (IC₅₀: 60 μg/mL; 72 h) and antiproliferative effects on mouse colorectal cancer (CRC) cells. CXCR4-IN-2 induces cell arrest in the G2/M phase and induces apoptosis.

HY-RS03397

CXCR1 Human Pre-designed siRNA Set A	Inhibitor
CXCR1 Human Pre-designed siRNA Set A contains three designed siRNAs for CXCR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS03404

Cxcr3 Mouse Pre-designed siRNA Set A	Inhibitor
Cxcr3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cxcr3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-119208

VUF11211	Inhibitor
VUF11211 is an allosteric inverse CXCR3 agonist with a K_d of 0.65 nM.

HY-125567

Antileukinate	Inhibitor
Antileukinate, a hexapeptide, is a potent inhibitor of CXC-chemokine receptor (CXCR). Antileukinate inhibits neutrophil chemotaxis and activation. Antileukinate can be used for the research of acute inflammation and injury.

HY-RS03410

CXCR6 Human Pre-designed siRNA Set A	Inhibitor
CXCR6 Human Pre-designed siRNA Set A contains three designed siRNAs for CXCR6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS03402

Cxcr2 Rat Pre-designed siRNA Set A	Inhibitor
Cxcr2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cxcr2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-W104862

4-Amino-D-phenylalanine	Inhibitor
4-Amino-D-phenylalanine ([D-Phe(4-NH2)), a cyclic pentapeptide, inhibits CXCL12 binding to CXCR4 in FC131, with an IC₅₀ of 0.1 μM.

HY-RS03405

Cxcr3 Rat Pre-designed siRNA Set A	Inhibitor
Cxcr3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cxcr3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-N0011R

Baohuoside I (Standard)	Inhibitor
Baohuoside I (Standard) is the analytical standard of Baohuoside I. This product is intended for research and analytical applications. Baohuoside I, a flavonoid isolated from Epimedium koreanum Nakai, acts as an inhibitor of CXCR4, downregulates CXCR4 expression, induces apoptosis and shows anti-tumor activity.

HY-RS03412

Cxcr6 Rat Pre-designed siRNA Set A	Inhibitor
Cxcr6 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cxcr6 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-P4109

vMIP-II (1-21)	Inhibitor
vMIP-II (1-21) (NT21MP) is an inhibitor of CXCR4. vMIP-II (1-21) interacts broadly with CC and CXC chemokine receptors. vMIP-II (1-21) inhibits CXCR4 by competing with 125I-SDF-1R for binding sites (IC₅₀=190 nM).

HY-15319A

(±)-AMG 487	Inhibitor
(±)-AMG 487 is a racemate of AMG 487. AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC₅₀s of 8.0 and 8.2 nM, respectively.

HY-RS03411

Cxcr6 Mouse Pre-designed siRNA Set A	Inhibitor
Cxcr6 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cxcr6 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-167945

AMD-3329	Inhibitor
AMD-3329 is a potent and selective anti-HIV-1 and HIV-2 agent, exhibiting activity by inhibiting virus replication through binding to the chemokine receptor CXCR4, which serves as a co-receptor for the entry of X4 viruses.

HY-131374

TN14003	Inhibitor
TN14003 is a CXCR4 inhibitor. TN14003 has antitumor activity.

HY-172154

SSB-2548	Inhibitor
SSB-2548 is a CXCR-4 inhibitor. SSB-2548 can inhibit the proliferation, migration and induce apoptosis of acute myeloid leukemia cells. SSB-2548 has good gastrointestinal absorption and can be used in the research of leukemia.

HY-162505

SQA1	Inhibitor
SQA1, a squaramide (SQA) derivative, is a CCR6 antagonist with a K_d of 250 nM. SQA1 is also a CXCR2 inhibitor. The intracellular pocket occupied by SQA1 overlaps with the G protein binding site and stabilizes the closed conformation of the intracellular pocket.

HY-160041

Olaptesed pegol	Inhibitor
Olaptesed pegol (NOX-A12) L-oligoribonucleotide aptamer targeting CXCL12 based on a pegylated structure. Olaptesed pegol neutralizes CXCL12, and CXCL12 inhibition mobilizes chronic lymphocytic leukemia cells into the circulation and prevents their homing into the protective microenvironment.

Name
Email *

	Sorry, but the email address you supplied was invalid.