2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. Adrenergic Receptor
  5. Adrenergic Receptor Antagonist

Adrenergic Receptor Antagonist

Adrenergic Receptor Isoform Comparison

Adrenergic Receptor Antagonists (436):

Cat. No. Product Name Effect Purity
  • HY-121383R
    Labetalol (Standard)
    		Antagonist
    Labetalol (Standard) is the analytical standard of Labetalol. This product is intended for research and analytical applications. Labetalol (AH5158) is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol can be used in the study of cardiovascular diseases, such as hypertension during pregnancy.
  • HY-135004
    SU-4029 dihydrochloride
    		Antagonist
    Su-4029 is an agent that interacts with alpha receptors. It negates the blockade of norepinephrine by the reversible adrenergic blocker phentolamine but not by the irreversible blocker Dibenamine, suggesting Su-4029 acts at the same site as these blockers. Su-4029 pretreatment results in three categories of responses to pressor phenylalkylamines: irreversible blockade of amines with no or only p-hydroxylation, reversible blockade of amines with beta-carbon hydroxylation, and no blockade or augmentation of amines with m and p-hydroxylation or m or p plus beta-hydroxylation. Su-4029 may deform the alpha receptor site affected by adrenergic blocking agents.
  • HY-B0371FR
    Terazosin (hydrochloride) (Standard)
    		Antagonist
    Terazosin (hydrochloride) (Standard) is the analytical standard of Terazosin (hydrochloride). This product is intended for research and analytical applications. Terazosin hydrochloride is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist. Terazosin hydrochloride works by relaxing blood vessels and the opening of the bladder. Terazosin hydrochloride has the potential for benign prostatic hyperplasia (BPH) and high blood pressure treatment.
  • HY-B1573A
    (±)-Butaclamol hydrochloride
    		Antagonist
    (±)-Butaclamol hydrochloride (AY-23,028) is the antagonist for adrenergic receptor and dopamine receptor. (±)-Butaclamol hydrochloride antagonizes amphetamine or Apomorphine (HY-12723)-induced stereotyped behaviors and emesis, inhibits discriminative avoidance behavior, and induces catalepsy in rats models.
  • HY-106684
    Ridazolol
    		Antagonist
    Ridazolol is a β-adrenergic receptor (βAR) antagonist. Ridazolol exhibits a high degree of selectivity for β-1 adrenergic receptor (β1AR) and possesses moderate intrinsic sympathomimetic activity (ISA). Ridazolol can competitively antagonize the relaxation effects induced by isoproterenol. Ridazolol is utilized in the research of cardiovascular diseases.
  • HY-B0661R
    Tamsulosin (Standard)
    		Antagonist
    Tamsulosin (Standard) is the analytical standard of Tamsulosin. This product is intended for research and analytical applications. Tamsulosin ((R)-(-)-YM12617 free base) is an inhibitor of α1-adrenergic receptor. Tamsulosin is used for the research of prostatic hyperplasia. Tamsulosin attenuates abdominal aortic aneurysm growth in animal models.
  • HY-101690
    QF0301B
    		Antagonist
    QF0301B is an α1 adrenergic receptor antagonist and a low α2 adrenoceptor, 5-HT2A, and histamine H1 receptor blocker.
  • HY-U00356
    Tertatolol
    		Antagonist
    Tertatolol is a potent antagonist of beta-adrenoceptor and 5-HT receptor, with unique renal vasodilatatory effects.
  • HY-U00367
    (4E)-SUN9221
    		Antagonist
    (4E)-SUN9221 is a potent antagonist of α1-adrenergic receptor and 5-HT2 receptor, with antihypertensive and anti-platelet aggregation activities.
  • HY-U00399
    Fiduxosin
    		Antagonist
    Fiduxosin is a potent α1-adrenoceptor antagonist, with Ki of 0.160 nM, 24.9 nM, and 0.920 nM for α1a-, α1b-, and α1d-adrenoceptors, respectively.
  • HY-U00110
    MG 1
    		Antagonist
    MG 1 is an α1 adrenergic receptor antagonist.
  • HY-U00365
    5-HT2 antagonist 1
    		Antagonist
    5-HT2 antagonist 1 is a potent antagonist of 5-HT2 receptor, with weak α1 adrenoceptor blocking activity.
  • HY-U00402
    Fenmetozole Tosylate
    		Antagonist
    Fenmetozole Tosylate is an antagonist of the actions of ethanol, also antagonizes α2-adrenergic receptor, and acts as an antidepressant agent.
  • HY-U00386
    Bometolol Hydrochloride
    		Antagonist
    Bometolol Hydrochloride is a beta-adrenergic blocking agent, used for the research of cardiovascular disease.
  • HY-U00283
    Falintolol, (Z)-
    		Antagonist
    Falintolol, (Z)-, a new β-adrenergic antagonist, is characterized by the presence of an oxime function.
  • HY-U00404
    Phentolamine Analogue 1
    		Antagonist
    Phentolamine Analogue 1 is an analogue of phentolamine. Phentolamine is a nonselective alpha-adrenergic antagonist.