Adenosine Receptor Agonist

Adenosine Receptor Agonists (78):

Cat. No.	Product Name	Effect	Purity

HY-A0181S

Adenosine monophosphate-¹³C₁₀,¹⁵N₅ dilithium	Agonist	≥99.0%
Adenosine monophosphate-¹³C₁₀,¹⁵N₅(AMP-¹³C₁₀,¹⁵N₅) is the ¹³C-labeled and ¹⁵N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

HY-N0586

Norisoboldine	Agonist
Norisoboldine is an orally active natural aryl hydrocarbon receptor (AhR) agonist. Norisoboldine, as a major isoquinoline alkaloid present in Radix Linderae, can be used for the research of Rheumatoid arthritis and Ulcerative colitis.

HY-19661

Tecadenoson	Agonist	99.69%
Tecadenoson (CVT-510) is a selective A1 adenosine receptor agonist.

HY-103183

CV1808	Agonist	≥98.0%
CV1808 (2-Phenylaminoadenosine) is a non-selective A2 adenosine receptor (A2 AR) agonist with K_is of 76 and 1450 nM for A2A and A3 adenosine receptor subtypes, respectively.

HY-106450

Binodenoson	Agonist	98.06%
Binodenoson (MRE-0470) is a potent and selective A2A adenosine receptor agonist (K_D=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging.

HY-128064

Adenosine amine congener	Agonist	99.23%
Adenosine amine congener (ADAC) is a selective A1 adenosine receptor agonist, can ameliorate noise- and Cisplatin-induced cochlear injury. Adenosine amine congener also has neuroprotective effects.

HY-N0092S

Inosine-2,8-d₂	Agonist	99.69%
Inosine-2,8-d₂ is the deuterium labeled Inosine. Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors.

HY-18687

APNEA	Agonist	98.96%
APNEA (N6-[2-(4-Aminophenyl)ethyl]adenosine) is a potent, non-selective A3 adenosine receptor agonist.

HY-105068

Apadenoson	Agonist	99.05%
Apadenoson is an adenosine analog with selective agonist activity for the adenosine A_2a receptor and induces coronary vasodilatation.

HY-101854

N6-(2-Phenylethyl)adenosine	Agonist	99.41%
N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine), an adenosine derivative, is a potent adenosine receptors (AR) agonist with K_i values of 11.8 nM, 30.1 nM, 0.63 nM for rat A₁AR, human A₁AR and hA₃AR, respectively.

HY-103187

HEMADO	Agonist	≥99.0%
HEMADO is a potent and selective adenosine A₃ receptor agonist with a K_i of 1.1 nM at the human A₃ subtype. HEMADO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-100032

PD 117519	Agonist	99.97%
PD 117519 (CI947) is an A_2A adenosine agonist which has shown oral antihypertensive activity in pharmacological animal models.

HY-136233

PSB 0777 ammonium	Agonist
PSB 0777 ammonium is a potent and selective adenosine A_2A receptor full agonist with K_i values of 44.4 nM, 360 nM for rat and human A_2A receptors, respectively. PSB 0777 ammonium has K_i values of ≥10000 nM, 541 nM for rat and human A₁ receptors, respectively. PSB 0777 ammonium shows poor brain penetrant and perorally non-absorbable effect. PSB 0777 ammonium has the potential for inflammatory bowel disease (IBS) research research.

HY-N0586A

Norisoboldine hydrochloride	Agonist	99.72%
Norisoboldine hydrochloride is an orally active natural aryl hydrocarbon receptor (AhR) agonist. Norisoboldine hydrochloride, as a major isoquinoline alkaloid present in Radix Linderae, can be used for the research of Rheumatoid arthritis and Ulcerative colitis.

HY-106007

Trabodenoson	Agonist	99.97%
Trabodenoson (INO-8875), an adenosine mimetic, is a highly selective Adenosine A1 receptor agonist. Trabodenoson (INO-8875) is used in the study for Primary Open-Angle Glaucoma.

HY-131032

KI-7	Agonist	99.16%
KI-7 is an A2B adenosine receptor positive allosteric modulator. KI-7 potentiates the cAMP accumulation induced by the non-selective A2B adenosine receptor agonist NECA (EC₅₀=445.8 nM). KI-7 also potentiates the cAMP accumulation induced by the selective A2B adenosine receptor agonist BAY 60-6583 as well as by adenosine with EC₅₀s of 2390 nM and 2550 nM, respectively.

HY-10915

LUF6096	Agonist	99.16%
LUF6096, a potent allosteric enhancer of the adenosine A3 receptor, is able to allosterically enhance agonist binding. LUF6096 shows low orthosteric affinity for any of the adenosine receptors. LUF6096 shows protective effects in myocardial ischemia/reperfusion injury.

HY-N0092R

Inosine (Standard)	Agonist
Inosine (Standard) is the analytical standard of Inosine. This product is intended for research and analytical applications. Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A₁ (A₁R) and A_2A (A_2AR) receptors. In Vitro:Inosine dose-dependently stimulates cAMP production mediated through the A_2AR. Inosine dose-dependently induces hA_2AR-mediated ERK1/2 phosphorylation. Inosine (100 μM; 24 hours) reduces oxidative stress in MES 23.5 cells cultured with astrocytes. In Vivo:Inosine (10-100 mg/kg; i.p.) exhibits antinociceptive effect in mice.

HY-13201

CGS 21680	Agonist
CGS 21680 is a selective adenosine A2A receptor agonist, with a K_i of 27 nM.

HY-A0181S2

Adenosine monophosphate-d₁₂ dilithium	Agonist
Adenosine monophosphate-d₁₂ (AMP-d₁₂) dilithium is deuterium labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

Name
Email *

	Sorry, but the email address you supplied was invalid.