2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W719847
    Orbifloxacin-d4 2714415-07-1
    Orbifloxacin-d4 is deuterium labeled Orbifloxacin.
    Orbifloxacin-d4
  • HY-W722081
    Baumycin C1 63084-42-4
    Baumycin C1 is an antitumor antibiotic.
    Baumycin C1
  • HY-W726164
    Gentamicin A 13291-74-2
    Gentamicin A is an antibiotic with good antibacterial activity to Gram-positive bacteria and negative bacteria. Gentamicin A has antibacterial activity against most methicillin-sensitive staphylococcus.
    Gentamicin A
  • HY-W728005
    Covidcil-19 1225177-95-6
    Covidcil-19 (compound C5) avidly binds to the revised attenuator hairpin structure of the SARS-CoV-2 frameshifting element (FSE) with a Kd of 11 nM. Covidcil-19 stabilizes the hairpin’s folded state and impairs frameshifting in cells. Covidcil-19 reduces frameshifting efficiency of the SARS-CoV-2 FSE and does not affect SARS-CoV-2 FSE RNA levels. Covidcil-19 inhibits a process essential for SARS-CoV-2 viral propagation.
    Covidcil-19
  • HY-W728085
    CPPD-Q 68054-78-4
    CPPD-Q is an antimicrobial agent and insecticide. CPPD-Q has an EC50 of 6.98 mg/L against Vibrio fischeri. At doses of 1 or 10 µg/mL, CPPD-Q exerts its insecticidal effect by inducing the production of reactive oxygen species (ROS) in the intestines of Caenorhabditis elegans.
    CPPD-Q
  • HY-W736195
    5-Hydroxy-4-oxo-L-norvaline 26911-39-7
    5-Hydroxy-4-oxo-L-norvaline is an antifungal antibiotic. 5-Hydroxy-4-oxo-L-norvaline can inhibit protein biosynthesis.
    5-Hydroxy-4-oxo-L-norvaline
  • HY-W739149
    Rifapentine-d8
    Rifapentine-d8 is deuterium labeled Rifapentine. Rifapentine (DL 473) is an antibiotic used in tuberculosis research.
    Rifapentine-d8
  • HY-W739930
    Desmethyl ofloxacin hydrochloride 402930-70-5
    Desmethyl ofloxacin hydrochloride is a metabolite of the fluoroquinolone antibiotic Ofloxacin (HY-B0125).
    Desmethyl ofloxacin hydrochloride
  • HY-W740028
    Cefditoren-d3 sodium
    Cefditoren-d3 (sodium) (ME 1206-d3) is deuterium labeled Cefditoren (sodium). Cefditoren sodium (ME 1206) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren sodium has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren sodium can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections.
    Cefditoren-d3 sodium
  • HY-W740165
    Desmethyl Levofloxacin hydrochloride 2254176-11-7
    Desmethyl Levofloxacin hydrochloride is an antibacterial agent with broad-spectrum antibacterial activity against a variety of pathogens. Desmethyl Levofloxacin hydrochloride effectively fights bacterial infections by inhibiting bacterial DNA synthesis. Studies on Desmethyl Levofloxacin hydrochloride have shown that it has potential in inhibiting respiratory infections.
    Desmethyl Levofloxacin hydrochloride
  • HY-W741041
    Fluoxastrobin-d4 1246833-67-9
    Fluoxastrobin-d4 is the deuterium labeled Fluoxastrobin. Fluoxastrobin is a fungicide agent.
    Fluoxastrobin-d4
  • HY-W741062
    15-Methylhexadeca Sphinganine 26048-10-2
    Sphinganine (d16:0 branched) is an iso-branched sphingolipid. It has been found as a component of ceramide-containing phospholipids in bacteria.
    15-Methylhexadeca Sphinganine
  • HY-W741555
    Dechlorogriseofulvin 3680-32-8
    Dechlorogriseofulvin (7-Dechlorogriseofulvin) is an antibiotic, and exhibits inhibitory activity against various plant pathogenic fungi. Dechlorogriseofulvin inhibits Botrytis cinerea, Rhizoctonia solani, Pythium ultimum, and Sclerotinia sclerotiorum with MIC of 40.0 µg/ml, 43.9 µg/ml, 81.7 µg/ml, and 28.5 µg/ml, respectively.
    Dechlorogriseofulvin
  • HY-W741556
    Dehydrogriseofulvin 3573-90-8
    Dehydrogriseofulvin can be isolated from Penicillium sp. Dehydrogriseofulvin inhibits Colletotrichum musae with MIC > 1 µg/scrip.
    Dehydrogriseofulvin
  • HY-W741557
    Griseofulvic Acid 469-54-5
    Griseofulvic acid is a metabolite of the antifungal Griseofulvin (HY-17583). It induces protein aggregation and tubulin polymerization in cell-free assays.
    Griseofulvic Acid
  • HY-W747311
    Ritipenem 84845-57-8
    Ritipenem is a penicillin antibiotic, that targets penicillin-binding protein with good affinity (IC50 in levels of ng/mL), and exhibits antibacterial properties. Ritipenem exhibits antiviral activity against Haemophilus influenzae.
    Ritipenem
  • HY-W747504
    TAN-420E 91700-93-5
    TAN-420E (Dihydroherbimycin A) is an antibiotic, that can be isolated from the fermentation product of Streptomyces hygroscopicus. TAN-420E exhibits cytotoxicity in cancer cells P-388 and KB. TAN-420E scavenges DPPH free radicals with an IC50 of 1.3 μM.
    TAN-420E
  • HY-W747507
    Reveromycin D 144860-70-8
    Reveromycin D is a bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells and has pH-dependent antifungal activity against C. albicans (MICs=2 and >500 μg/mL at pH 3 and 7.4, respectively).2 Reveromycin D also inhibits proliferation of KB and K562 cells (IC50s=1.6 and 1.3 μg/mL, respectively).
    Reveromycin D
  • HY-W747516
    Butylcycloheptylprodigiosin 352304-41-7
    Butylcycloheptylprodigiosin is the secondary metabolite produced by some bacteria, such as Streptomyces. Butylcycloheptylprodigiosin is a red-pigmented antibiotic and exhibits cytotoxicity against cancer cell MCF-7 and HDF.
    Butylcycloheptylprodigiosin
  • HY-W747994
    Atramycin A 137109-48-9
    Atramycin A is an isotetracenone type antitumor antibiotic.
    Atramycin A
Cat. No. Product Name / Synonyms Application Reactivity