2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W654342
    Spermine-d20
    Spermine-d20 (NSC 268508-d20) is deuterium labeled Spermine. Spermine (NSC 268508) functions directly as a free radical scabenger to protect DNA from free radical attack. Spermine has antiviral effects.
    Spermine-d20
  • HY-W673589
    Hexacosane, 2-Methyl- 1561-02-0
    2-Methylhexacosane is a saturated hydrocarbon and an insect pheromone. It has been found in the cuticle of M. dasystomus females, but not males, where it contributes to the mating behavior of males, as well as in D. melanogaster females where it modulates aggression of males towards females. 2-methylhexacosane has also been found in yellow jacket (V. vulgaris) trail extracts.
    Hexacosane, 2-Methyl-
  • HY-W679754
    Pentacosafluorotridecanoic Acid 72629-94-8
    Perfluorotridecanoic acid (PFTrDA) is a perfluoroalkyl substance (PFAS). Embryo larval exposure of PFTrDA induces yolk sac edema and increases mRNA expression of thyroid hormone synthesis genes, including tshβ, in zebrafish when used at concentrations of 0.1 and 0.3 mg/L, respectively. PFTrDA (10 mg/kg) decreases serum testosterone and luteinizing hormone levels, testis palmitic acid, linoleic acid, and oleic acid levels, and the number of Leydig cells in rats in late puberty. Maternal plasma levels of PFTrDA during gestation are positively associated with the development of eczema in female, but not male, infants, and liver levels of PFTrDA are higher in cancerous human livers compared with non-cancerous human livers. It has been found in marine mammals.
    Pentacosafluorotridecanoic Acid
  • HY-W683885
    Dimabefylline 1703-48-6
    Dimabefylline is an antimicrobial compound.
    Dimabefylline
  • HY-W685561
    3-Oxo-C8-HSL 216596-70-2
    3-Oxo-C8-HSL (N-(3-Oxooctanoyl)-l-homoserine lactone) is an autoinducer pheromone. 3-Oxo-C8-HSL is a TraR-regulated promoter. 3-Oxo-C8-HSL significantly stimulates tra gene expression.
    3-Oxo-C8-HSL
  • HY-W686763
    Triacetylphloroglucinol 2161-87-7
    Triacetylphloroglucinol (2,4,6-Triacetylphloroglucinol) is a C3-symmetric three-dimensional bridged ligand. It has been used in the synthesis of various compounds including trinuclear vanadium Schiff base complexes, copper complexes and anthelmintics.
    Triacetylphloroglucinol
  • HY-W698254
    Fluopsin F 31323-26-9
    Fluopsin F is an antibiotic containing metallic iron with strong anti-Gram-positive and negative bacteria activity and anti-tumor activity.
    Fluopsin F
  • HY-W700241
    Norharman-d7 1216503-21-7
    Norharman-d7 is deuterium labeled Norharmane. Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC50 values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings.
    Norharman-d7
  • HY-W702986
    Hydroxy darunavir 1130635-75-4
    Hydroxy darunavir is a metabolite of the HIV-1 protease inhibitor Darunavir (HY-17040).
    Hydroxy darunavir
  • HY-W703398
    Monopropyl phthalate 4376-19-6
    Monopropyl phthalate is a compound derived from the hydrolysis of Dipropyl phthalate (DPrP). Monopropyl phthalate is hydrolyzed to PA. DPrP shows significant dose-dependent toxic effects on K. brevis.
    Monopropyl phthalate
  • HY-W704321
    Diploicin 527-93-5
    Diploicin is a diphenyl ether lactone compound with anti-gram-positive bacteria activity, which is found in lichens.
    Diploicin
  • HY-W705651
    Econazole nitrate-d6 2469273-41-2
    Econazole nitrate-d6 is deuterium labeled Econazole (nitrate). Econazole nitrate is an imidazole class antifungal medication. Econazole nitrate also has antibacterial activity.
    Econazole nitrate-d6
  • HY-W706112
    Chloramphenicol-d5-2
    Chloramphenicol-d5-2 is the deuterium labeled Chloramphenicol (HY-B0239). Chloramphenicol is an orally active, potent and broad-spectrum antibiotic.
    Chloramphenicol-d5-2
  • HY-W707365
    Docosyl trans-ferulate 101927-24-6
    Docosyl trans-ferulate (compound 2) is an antiviral compound. Docosyl trans-ferulate exhibits anti-HIV-1 activity in anti-syncytial assays using the ΔTat/revMC99 virus and 1A2 cell line systems.
    Docosyl trans-ferulate
  • HY-W710314
    3,4-Dimethoxy-1,2-dimethyl-9H-carbazole 75139-39-8
    3,4-Dimethoxy-1,2-dimethyl-9H-carbazole is a carbazole alkaloid that can be used in the synthesis of baccamycin.
    3,4-Dimethoxy-1,2-dimethyl-9H-carbazole
  • HY-W713365
    Eltrombopag-d3 1133710-20-9
    Eltrombopag-d3 (SB-497115-d3) is deuterium labeled Eltrombopag. Eltrombopag (SB-497115) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag can be used for the research of cardiovascular. Eltrombopag also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag can induce apoptosis in hepatocellular carcinomab (HCC) as well.
    Eltrombopag-d3
  • HY-W713855
    (4-Aminobenzoyl)-D-glutamic acid 5959-18-2
    (4-Aminobenzoyl)-D-glutamic acid (Compound 17) exhibits competitive inhibitory activity against H2-pteroate synthesis system, which affects the synthesis of folate, thereby inhibiting growth of bacteria.
    (4-Aminobenzoyl)-D-glutamic acid
  • HY-W714002
    Feglymycin 209335-49-9
    Feglymycin is a HIV replication inhibitor. Feglymycin is also an antibiotic peptide that has antibacterial activity (MIC: 32-64 μg/mL for Staphylococcus aureus).
    Feglymycin
  • HY-W714076
    Ametoctradin 865318-97-4
    Ametoctradin is a potent Qo site inhibitor of bc1 complex in mitochondrial respiration. Ametoctradin is a highly selective and effective Oomycete-specific fungicide that can be used against late blight and downy mildews.
    Ametoctradin
  • HY-W714837
    5-Phenyllevulinic acid 3183-15-1
    5-Phenyllevulinic acid (4-Oxo-5-phenylpentanoic acid) is an endogenous fungal metabolite with inhibitory activity against the bacterium B. megaterium, the plant pathogenic fungus S. tritici, and the alga C. fusca. 5-Phenyllevulinic acid is also an intermediate in the synthesis of σ receptor ligands. 5-Phenyllevulinic acid holds potential for research in the field of anti-infection studies .
    5-Phenyllevulinic acid
Cat. No. Product Name / Synonyms Application Reactivity