2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-113764
    N-Butanoyl-DL-homoserine lactone 98426-48-3 ≥98.0%
    N-Butanoyl-DL-homoserine lactone ((Rac)-C4-HSL) is a racemic mixture of N-Butanoyl-D-homoserine lactone and N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa.
    N-Butanoyl-DL-homoserine lactone
  • HY-114437
    Fusion Inhibitory Peptide 75539-79-6 99.93%
    Fusion Inhibitory Peptide (Z-D-Phe-Phe-Gly-OH, FIP, Virus Replication Inhibitory Peptide) is a potent inhibitor of the virus replication, by inhibiting the membrane fusing activity of a viral glycoprotein.
    Fusion Inhibitory Peptide
  • HY-114495
    Caerulomycin A 21802-37-9 ≥98.0%
    Caerulomycin A (Cerulomycin; Caerulomycin), an antifungal compound, induces generation of T cells, enhances TGF-β-Smad3 protein signaling via suppressing interferon-γ-induced STAT1 signaling. Antifungal and antibiotic activity, and used in autoimmune diseases.
    Caerulomycin A
  • HY-114818
    4-(tert-Butyl)-benzhydroxamic Acid 62034-73-5 99.49%
    4-(tert-Butyl)-benzhydroxamic Acid is a PqsR antagonist with IC50s of 12.5 μM and 23.6 μM for E. coli and P. aeruginosa, respectively. 4-(tert-Butyl)-benzhydroxamic Acid reduces the production of the virulence factor pyocyanin in P. aeruginosa with an IC50 of 87.2 μM.
    4-(tert-Butyl)-benzhydroxamic Acid
  • HY-115249
    Metronidazole acetic acid 1010-93-1 99.88%
    Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa.
    Metronidazole acetic acid
  • HY-115550
    Chalcone 4 hydrate 1202866-96-3 ≥98.0%
    Chalcone 4 hydrate is an anti-parasite agent, inhibits the growth of Babesia and Theileria.
    Chalcone 4 hydrate
  • HY-115574
    RSV L-protein-IN-1 851658-10-1 98.09%
    RSV L-protein-IN-1 (compound D) is a potent inhibitor of Respiratory syncytial virus (RSV) (EC50=0.021 μM). RSV L-protein-IN-1 inhibits Polymerase (IC50=0.089 μM)，and blocks RSV mRNA synthesis by inhibiting guanylation of viral transcripts. RSV L-protein-IN-1 shows moderate cytotoxicity (CC50=8.4 μM，HEp-2)，also exhibits activity and lowers virus titers in mouse models of RSV infection.
    RSV L-protein-IN-1
  • HY-116536
    N-3-Oxo-tetradecanoyl-L-homoserine lactone 177158-19-9 99.90%
    N-3-Oxo-tetradecanoyl-L-homoserine lactone (oxo-C14-HSL) is a rhizobacterial inducer and can improve basic defense against nematodes.
    N-3-Oxo-tetradecanoyl-L-homoserine lactone
  • HY-116993
    N-(Hydroxymethyl)nicotinamide 3569-99-1 99.82%
    N-(Hydroxymethyl)nicotinamide is an antimicrobic agent.
    N-(Hydroxymethyl)nicotinamide
  • HY-117005
    C450-0730 1036730-46-7
    C450-0730 is an antagonist targeting the AHL membrane-bound sensor kinase and is an antagonist of the nine-transmembrane protein LuxN of Vibrio harveyi . C450-0730 competitively binds to the LuxN AI-1 binding site and specifically antagonizes the LuxN/AI-1 quorum sensing signal in Vibrio harveyi. The inhibitory activity of C450-0730 against LuxNI209F was not significant.
    C450-0730
  • HY-117089
    Tetraconazole 112281-77-3
    Tetraconazole, a chiral triazole fungicide, is widely used for the prevention of plant disease in wheat fields. Tetraconazole alters the methionine and ergosterol biosynthesis pathways in Saccharomyces yeasts promoting changes on volatile derived compounds.
    Tetraconazole
  • HY-117145
    Thiophene-2 420089-51-6 ≥99.0%
    Thiophene-2 (TP2) is a specific polyketide synthase 13 (Pks13) inhibitor. Thiophene-2 inhibits mycolic acid biosynthesis and rapidly leads to mycobacterial cell death. Thiophene-2 is active against Mycobacterium tuberculosis with a MIC value of 1 μM, and has potent anti-tuberculosis activity.
    Thiophene-2
  • HY-117319
    Indolmycin 21200-24-8 99.90%
    Indolmycin (TAK-083), an antibiotic, is a competitive inhibitor of prokaryotic tryptophanyl-tRNA synthetase (TrpS). Indolmycin (TAK-083) possesses both anti-viral and anti-bacterial activity.
    Indolmycin
  • HY-118099
    Florfenicol amine hydrochloride 108656-33-3 99.45%
    Florfenicol amine hydrochloride is a metabolite of Florfenicol (HY-B1374). Florfenicol inhibits bacterial protein synthesis by binding to 50S and 70S subunits in the ribosome to abolish the activity of peptidyltransferase. Florfenicol, is a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases.
    Florfenicol amine hydrochloride
  • HY-118659
    Benzalphthalide 575-61-1 98.04%
    Benzalphthalide (3-Benzylidenephthalide), a phthalate compound, is an insecticide.
    Benzalphthalide
  • HY-119614
    Niridazole 61-57-4 98.75%
    Niridazole is an anaerobic and microaerophilic bacterial inhibitor with IC50 values ranging from 0.0037 to 1.0 μg/mL.
    Niridazole
  • HY-119649
    Flonicamid 158062-67-0 99.87%
    Flonicamid (IKI220) is a novel systemic insecticide with selective activity against hemipterous pests. The main insecticidal mechanism of flonicamid is starvation based on the inhibition of stylet penetration to plant tissues.
    Flonicamid
  • HY-119691
    Alamifovir 193681-12-8
    Alamifovir (LY582563; MCC-478), a purine nucleotide analogue proagent, shows potent activity against wild type and lamivudine resistant hepatitis B virus (HBV). Alamifovir has high activity against HBV replication and sustained antiviral effect.
    Alamifovir
  • HY-119821
    Terphenyllin 52452-60-5
    Terphenyllin is a naturally abundant p-terphenyl metabolite isolated from the coral derived fungus Aspergillus candidus, has significant α-glucosidase inhibitory activity.
    Terphenyllin
  • HY-119847
    Abafungin 129639-79-8 99.10%
    Abafungin, a antifungal agent, inhibitis the transmethylation at the C-24 position of the sterol side chain, catalyzed by the enzyme sterol-C-24-methyltransferase.
    Abafungin
Cat. No. Product Name / Synonyms Application Reactivity