2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B0289
    Erdosteine 84611-23-4 99.62%
    Erdosteine inhibits lipopolysaccharide (LPS)-induced NF-κB activation. Erdosteine has muco-modulatory, anti-bacterial, anti-inflammatory and anti-oxidant effects.
    Erdosteine
  • HY-N7922
    Urolithin M5 91485-02-8
    Urolithin M5 is a neuraminidase inhibitor that can be isolated from Ganlanye. Urolithin M5 has antiviral activity in vitro and in vivo by inhibiting the activity of viral NA. Urolithin M5 can increase the survival rate and improve pulmonary edema in pr8-infected mouse models. Urolithin M5 can be used in anti-influenza research.
    Urolithin M5
  • HY-Y0532
    N-Chlorosuccinimide 128-09-6 ≥98.0%
    N-Chlorosuccinimide can enhance the antimicrobial effect of Benzalkonium chloride (HY-B2232) on biofilm Pseudomonas aeruginosa.
    N-Chlorosuccinimide
  • HY-121935
    Tecnazene 117-18-0 99.96%
    Tecnazene (2,3,5,6-Tetrachloronitrobenzene) is a fungicide and is used as a sprout inhibitor on stored potatoes.
    Tecnazene
  • HY-17422R
    Acyclovir (Standard) 59277-89-3
    Acyclovir (Standard) is the analytical standard of Acyclovir. This product is intended for research and analytical applications. Acyclovir (Aciclovir) is a potent, orally active antiviral agent. Acyclovir has antiherpetic activity with IC50 values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir induces cell cycle perturbation and apoptosis. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia.
    Acyclovir (Standard)
  • HY-131576A
    Thymidine 5′-diphosphate sodium 108322-12-9 ≥99.0%
    Thymidine 5′-diphosphate (dTDP) sodium is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate sodium is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg2+. Thymidine 5′-diphosphate sodium is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate.
    Thymidine 5′-diphosphate sodium
  • HY-W010538
    trans-4-Methylcyclohexanamine 2523-55-9 ≥98.0%
    trans-4-Methylcyclohexanamine is an intermediate and can be used for the development of T. cruzi enzyme inhibitor.
    trans-4-Methylcyclohexanamine
  • HY-W013040
    Pyrazine 290-37-9 98.94%
    Pyrazine is an aromatic azaheterocycle containing two nitrogen atoms, known for its electron-deficient nature. Pyrazine is a key pharmacophore in various drugs, including anti-inflammatory, anticancer, and antimicrobial agents, with significant applications in pharmaceuticals, flavor, fragrance, and food industries.
    Pyrazine
  • HY-W018582
    N-Phenylacrylamide 2210-24-4 ≥98.0%
    N-Phenylacrylamide is a special polymer showing high affinity with Ochratoxin A, a colorless and crystalline mycotoxin compound. N-Phenylacrylamide can be applied in the field of mycotoxin extraction, and be used for the security research of agricultural commodities and foods made from cereals and grapes.
    N-Phenylacrylamide
  • HY-W145518
    Pectin 9000-69-5
    Pectin is a heteropolysaccharide, derived from the cell wall of higher plants. Pectin involves in the formation of nanoparticles as a delivery vehicle of agents. Pectin is also an adsorbent, a broad-spectrum antimicrobial agent that binds to bacteria toxins and other irritants in the intestinal mucosa, relieves irritated mucosa.
    Pectin
  • HY-128365
    Neticonazole hydrochloride 130773-02-3 99.96%
    Neticonazole hydrochloride is an imidazole derivative and a potent and long-acting antifungal agent. Neticonazole hydrochloride has anti-infection and anti-cancer effects.
    Neticonazole hydrochloride
  • HY-135327
    Amphotericin B methyl ester 36148-89-7
    Amphotericin B methyl ester is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B methyl ester is the cholesterol-binding compound possesses significant antifungal activity. Amphotericin B methyl ester disrupts HIV-1 particle production and potently inhibits HIV-1 replication.
    Amphotericin B methyl ester
  • HY-136303
    GS-704277 1911579-04-8 99.63%
    GS-704277 is an alanine metabolite of Remdesivir (HY-104077). GS-704277 is further hydrolyzed to GA-441524 (HY-103586) with antiviral activity. Remdesivir, a nucleoside analogue with effective antiviral activity, is highly effective in the control of SARS-CoV-2 (COVID-19) infection.
    GS-704277
  • HY-159502
    Surlorian 1467605-57-7 99.75%
    Surlorian is a ryanodine receptor (RyR) stabilizer.
    Surlorian
  • HY-18595
    BI 224436 1155419-89-8 99.74%
    BI 224436 is a novel HIV-1 noncatalytic site integrase inhibitor with EC50 values of less than 15 nM against different HIV-1 laboratory strains.
    BI 224436
  • HY-B1050
    Gemifloxacin mesylate 210353-53-0 99.76%
    Gemifloxacin mesylate (SB-265805S; LB-20304a) is an orally active broad-spectrum quinolone antibacterial antibiotic. Gemifloxacin mesylate inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in vitro efficacy study, particularly Streptococci and Staphylococci. Gemifloxacin mesylate has been used in the research of respiratory tract infections.
    Gemifloxacin mesylate
  • HY-103643
    Fumagillol 108102-51-8 ≥98.0%
    Fumagillol is a direct precursor of fumagillin. Fumagillin, as an antimicrobial agent, is a potent and selective inhibitor of angiogenesis.
    Fumagillol
  • HY-122907
    JNJ4796 2241664-16-2 99.94%
    JNJ4796 is an oral active fusion inhibitor of influenza virus, neutralizing influenza A group 1 viruses by inhibiting hemagglutinin (HA)-mediated fusion. JNJ4796 mimics the functionality of the broadly neutralizing antibodies (bnAbs).
    JNJ4796
  • HY-148072
    MM3122 2574390-27-3 99.20%
    MM3122 is a selective type II transmembrane serine protease (TMPRSS2) inhibitor with an IC50 value of 0.34 nM. MM3122 effectively blocks TMPRSS2, thereby inhibiting the entry of SARS-CoV-2 and MERS-CoV into human cells.
    MM3122
  • HY-148564
    TBI-166 1353734-12-9 98.00%
    TBI-166, a riminophenazine analogue, is an orally active anti-tuberculosis agent with fewer adverse reactions than the lead riminophenazine compound, Clofazimine (HY-B1046) .
    TBI-166
Cat. No. Product Name / Synonyms Application Reactivity