2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-U00218
    McN5691 99254-95-2
    McN5691 is a voltage-sensitive calcium channel blocker.
    McN5691
  • HY-U00231
    KF 13218 127654-03-9
    KF 13218 is a potent, selective and long lasting thromboxane B2 (TXB2) synthase inhibitor with an IC50 value of 5.3±1.3 nM.
    KF 13218
  • HY-U00236
    PD0176078 248922-46-5 99.80%
    PD0176078 is a newly found N-type Calcium channel blocker.
    PD0176078
  • HY-U00284
    AE0047 Hydrochloride 116308-56-6
    AE0047 Hydrochloride is a calcium blocker, used in the research of hypertensive disease.
    AE0047 Hydrochloride
  • HY-U00301
    Anti-hypertensive sulfonanilide 1 129280-22-4
    Anti-hypertensive sulfonanilide 1 is a potent antihypertensive agent extracted from patent EP0338793A2, compound XVIIIa,b*, example No.1.
    Anti-hypertensive sulfonanilide 1
  • HY-U00313
    Tropodifene 15790-02-0
    Tropodifene (Tropaphen) is an α-Adrenergic receptor inhibitor.
    Tropodifene
  • HY-U00329
    Implitapide Racemate 177277-99-5
    Implitapide Racemate is the racemate of Implitapide. Implitapide is a microsomal triglyceride transfer protein (MTP) inhibitor.
    Implitapide Racemate
  • HY-U00336
    NEP-IN-2 145775-14-0
    NEP-IN-2 is an inhibitor of neutral endopeptidase, used in the research of proliferation in atherosclerosis, restenosis.
    NEP-IN-2
  • HY-U00356
    Tertatolol 83688-84-0
    Tertatolol is a potent antagonist of beta-adrenoceptor and 5-HT receptor, with unique renal vasodilatatory effects.
    Tertatolol
  • HY-U00365
    5-HT2 antagonist 1 191592-09-3
    5-HT2 antagonist 1 is a potent antagonist of 5-HT2 receptor, with weak α1 adrenoceptor blocking activity.
    5-HT2 antagonist 1
  • HY-U00367
    (4E)-SUN9221 222318-55-0
    (4E)-SUN9221 is a potent antagonist of α1-adrenergic receptor and 5-HT2 receptor, with antihypertensive and anti-platelet aggregation activities.
    (4E)-SUN9221
  • HY-U00369
    FCE 28654 169474-77-5
    FCE 28654 is an inhibitor of acylCoA: cholesterol acyltransferase (ACAT), weakly inhibiting ACAT in microsomes from rabbit aorta and intestine, and monkey liver, with IC50s of 2.55, 1.08 and 5.69 μM, respcetively.
    FCE 28654
  • HY-U00370
    Thrombin inhibitor 1 855998-46-8
    Thrombin inhibitor 1 is a potent thrombin inhibitor (Ki=0.66 nM, 2xaPTT=0.43 μM).
    Thrombin inhibitor 1
  • HY-U00378
    Glycerol derivative 1 128400-55-5
    Glycerol derivative 1 is a Glycerol derivative extracted from patent EP 672415 A1, compound (1).
    Glycerol derivative 1
  • HY-U00386
    Bometolol Hydrochloride 65023-16-7
    Bometolol Hydrochloride is a beta-adrenergic blocking agent, used for the research of cardiovascular disease.
    Bometolol Hydrochloride
  • HY-U00393
    Arrhythmic-Targeting Compound 1 136079-82-8
    Arrhythmic-Targeting Compound 1 is used for the research of arrhythmic disease, with nitrogen-containing spirocycles.
    Arrhythmic-Targeting Compound 1
  • HY-U00397
    CB1 antagonist 1 890037-68-0
    CB1 antagonist 1 is an antagonist of CB1 receptor, used in the research of metabolic syndrome and obesity, neuroinflammatory disorders, cognitive disorders and psychosis, gastrointestinal disorders, and cardiovascular conditions.
    CB1 antagonist 1
  • HY-U00413
    5-HT3-In-1 186348-68-5
    5-HT3-In-1 is extracted from patent EP0748807A1, compound example 8. It shows 5-HT3 inhibition activity.
    5-HT3-In-1
  • HY-W016704
    2,5-Dihydroxybenzoic acid sodium 4955-90-2
    2,5-Dihydroxybenzoic acid (sodium) (Gentisic acid (sodium)) is a phenolic compound. 2,5-Dihydroxybenzoic acid (sodium) restores mean arterial pressure and reduces blood lactate concentration in animal models of sepsis and septic shock. 2,5-Dihydroxybenzoic acid (sodium) can be used in the study of septic shock related diseases.
    2,5-Dihydroxybenzoic acid sodium
Cat. No. Product Name / Synonyms Application Reactivity