2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-U00040
    PAF-AN-1 115621-84-6
    PAF-AN-1 is a platelet activating factor receptor (PAF) antagonist.
    PAF-AN-1
  • HY-U00086
    Darodipine 72803-02-2
    Darodipine (PY 108-068, PY-108068) is a potent calcium channel antagonist.
    Darodipine
  • HY-U00110
    MG 1 148274-76-4
    MG 1 is an α1 adrenergic receptor antagonist.
    MG 1
  • HY-U00113
    Bunaftide 32421-46-8
    Bunaftide (Bunaftine; Bunaphtide; Meregon) is an antiarrhythmic agent.
    Bunaftide
  • HY-U00135
    Calcium channel-modulator-1 136941-70-3 98.77%
    Calcium channel-modulator-1 is a calcium channel modulator; blocks aortic contraction with an IC50 of 0.8 μM.
    Calcium channel-modulator-1
  • HY-U00136
    Win-62005 152633-54-0
    Win-62005 is a cyclic AMP phosphodiesterase III (PDE III) inhibitor with Kis of 25 and 26 nM for rat heart and canine aorta, respectively.
    Win-62005
  • HY-U00143
    N-0861 racemate 121241-87-0
    N-0861 racemate is the racemate of N-0861. N-0861 is a selective adenosine A1 receptor antagonist.
    N-0861 racemate
  • HY-U00147
    Nicotinoyl cyclandelate 39537-99-0
    Nicotinoyl cyclandelate can be used to lower the perfusion pressure of cerebral blood vessels and the blood pressure of femoral artery.
    Nicotinoyl cyclandelate
  • HY-U00149
    Drobuline hydrochloride 68162-52-7
    Drobuline hydrochloride is an anti-arrhythmic agent with cardiac depressant.
    Drobuline hydrochloride
  • HY-U00151
    Dopropidil 79700-61-1
    Dopropidil is a novel anti-anginal calcium ion modulating agent, possessing intracellular calcium antagonist activity and anti-ischemic effects in several predictive animal models.
    Dopropidil
  • HY-U00173
    U89232 134017-78-0
    U-89232 appears to be a cardioselective KATP channel opener.
    U89232
  • HY-U00182
    DU717 59943-31-6
    DU-717 is an antihypertensive agent.
    DU717
  • HY-U00183
    Epanolol 86880-51-5
    Epanolol (Visacor; ICI141292) is a potent β-adrenoceptor partial agonist with a greater affinity for β1- than β2-adrenoceptors.
    Epanolol
  • HY-U00184
    Timepidium bromide 35035-05-3
    Timepidium bromide (Sesden; SA504) is an anticholinergic agent.
    Timepidium bromide
  • HY-U00188
    A81988 141887-34-5
    A81988 is a potent, competitive, non-peptidic antagonist of angiotensin AT1 receptors.
    A81988
  • HY-U00191
    GP2-114 130783-39-0
    GP2-114 (GP-2-114) produces current-dependent cardiovascular action when administered by transdermal iontophoresis.
    GP2-114
  • HY-U00201
    KRN4884 152802-84-1
    KRN4884 is a K+ channel opener. In the presence of intracellular ATP (1 mM), KRN4884 (0.1-3 μM) activates KATP channels in a concentration-dependent manner (EC50=0.55 μM).
    KRN4884
  • HY-U00202
    LY285434 159748-08-0
    LY285434 is a suitable angiotensin II receptor antagonist.
    LY285434
  • HY-U00209
    Benzofurodil 3447-95-8
    Benzofurodil is a cardiotonic, which is used for the chronic treatment of congestive heart failure.
    Benzofurodil
  • HY-U00211
    CS476 41177-35-9
    CS476 is a potent hypoglycaemic agent.
    CS476
Cat. No. Product Name / Synonyms Application Reactivity