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amine-reactive

" in MedChemExpress (MCE) Product Catalog:

52

Inhibitors & Agonists

30

Fluorescent Dye

4

Biochemical Assay Reagents

2

Click Chemistry

1

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1041
    ICG-OSu

    ICG NHS ester

    		 Fluorescent Dye Cancer
    ICG-OSu (ICG NHS ester) is a near-infrared fluorescent agent ICG derivative. ICG-OSu is amine-reactive and has been widely used to design in vivo imaging probes .
    ICG-OSu
  • HY-D1352A
    Sulfo-Cyanine7 NHS ester TEA

    		Fluorescent Dye Others
    Sulfo-Cyanine7 NHS ester (TEA) is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester (TEA) reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
    Sulfo-Cyanine7 NHS ester TEA
  • HY-147117
    NHS-SS-Ac

    		Biochemical Assay Reagents Others
    NHS-SS-Ac is an amine-reactive product synthesized from acetic acid .
    NHS-SS-Ac
  • HY-D0135
    12-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid

    		Fluorescent Dye Others
    12-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid is an amine-reactive fluorescent dye .
    12-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid
  • HY-D1089
    6-JOE, SE

    		Fluorescent Dye Others
    6-JOE, SE is an amine-reactive fluorescent probe and is suitable for postsynthetic labeling of amino-modified oligonucleotides .
    6-JOE, SE
  • HY-131097
    Malachite green isothiocyanate

    		Fluorescent Dye Others
    Malachite green isothiocyanate is an amine-reactive probe that reacts with amines to give the corresponding thiourea. Malachite green isothiocyanate is a reagent that has been used for the measurement of concentration of protein .
    Malachite green isothiocyanate
  • HY-D1352
    Sulfo-Cyanine7 NHS ester potassium

    		Fluorescent Dye Others
    Sulfo-Cyanine7 NHS ester potassium is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
    Sulfo-Cyanine7 NHS ester potassium
  • HY-D1049
    DNP-X acid

    6-((2,4-Dinitrophenyl)amino)hexanoic acid

    		 Fluorescent Dye Metabolic Disease
    DNP-X acid (6-((2,4-Dinitrophenyl)amino)hexanoic acid), an amine-reactive building block for developing a probe, can be recognized by anti-DNP antibodies. DNP-X acid is also an excellent amine-reactive FRET quencher paired with Trp or Tyr.
    DNP-X acid
  • HY-D0115
    7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester

    		DNA Stain Others
    7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is a blue fluorescent dye for labeling proteins and nucleic acids .
    7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester
  • HY-W093254A
    Poly(ethylene glycol) bis(carboxymethyl) ether (Mn 250)

    		Biochemical Assay Reagents Others
    Poly(ethylene glycol) bis(carboxymethyl) ether (Mn 250) is an amine-reactive crosslinking agent .
    Poly(ethylene glycol) bis(carboxymethyl) ether (Mn 250)
  • HY-D0799
    Sulfo-NHS-LC-Biotin sodium
    3 Publications Verification

    		 Fluorescent Dye Others
    Sulfo-NHS-LC-Biotin sodium is an amine-reactive biotinylation reagent that can be used for antibody labeling .
    Sulfo-NHS-LC-Biotin sodium
  • HY-W093254B
    Poly(ethylene glycol) bis(carboxymethyl) ether (Mn 600)

    		Biochemical Assay Reagents Others
    Poly(ethylene glycol) bis(carboxymethyl) ether (Mn 600) is an amine-reactive crosslinking agent .
    Poly(ethylene glycol) bis(carboxymethyl) ether (Mn 600)
  • HY-D1774
    5-ROX-SE

    		Fluorescent Dye Others
    5-ROX-SE is the amine-reactive form of 5-carboxy-X-rhodamine single isomer.
    5-ROX-SE
  • HY-D1050
    DNP-X, SE
    1 Publications Verification

    6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester

    		 Fluorescent Dye Metabolic Disease
    DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester), the DNP-X acid modified by succinimidyl ester, is an amine-reactive building block for developing a probe, which can be recognized by anti-DNP antibodies. DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester) is also an excellent amine-reactive FRET quencher paired with Trp or Tyr.
    DNP-X, SE
  • HY-D2290
    Demethoxy-BODIPY TMR NHS ester

    		Fluorescent Dye Others
    Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .
    Demethoxy-BODIPY TMR NHS ester
  • HY-D0048
    5-TAMRA-SE
    2 Publications Verification

    5-TAMRA-NHS ester; 5-Carboxytetramethylrhodamine succinimidyl ester

    		 Fluorescent Dye Others
    5-TAMRA-SE is an amine-reactive fluorescent agent, and its conjugate produces bright, pH-insensitive orange-red fluorescence with good photostability.
    5-TAMRA-SE
  • HY-D0026
    AMCA,SE

    7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester

    		 Fluorescent Dye Others
    7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester is a bioReagent, suitable for fluorescence, can be used for amine-reactive labeling.
    AMCA,SE
  • HY-D0799A
    Sulfo-NHS-LC-Biotin

    		Fluorescent Dye
    Sulfo-NHS-LC-Biotin is an amine-reactive ester derivative of biotin and cannot pass the intact blood-retinal barrier. It can be used to assess vascular permeability of the brain and retinal vasculature.
    Sulfo-NHS-LC-Biotin
  • HY-111496
    Sulfo-NHS-SS-Biotin sodium
    2 Publications Verification

    		 Fluorescent Dye Others
    Sulfo-NHS-SS-biotin is a long-chain cleavable and cell-impermeant amine-reactive biotinylation reagent. Sulfo-NHS-SS-biotin can be used for the labeling and purifying of cell-surface protein .
    Sulfo-NHS-SS-Biotin sodium
  • HY-W395122
    Mal-PEG1-PNP-carbonate

    		Biochemical Assay Reagents Others
    Mal-PEG1-PNP-carbonate is a amine-reactive compound. PNP is a good leaving group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
    Mal-PEG1-PNP-carbonate
  • HY-D0029
    5(6)-Aminofluorescein
    1 Publications Verification

    5(6)-AFM; Fluoresceinamine mixed isomers

    		 Fluorescent Dye Others
    5(6)-Aminofluorescein (5(6)-AFM) is a a precursor for synthesis of 5(6)-FITC (HY-15941). 5(6)-FITC is an amine-reactive derivative of fluorescein dye.
    5(6)-Aminofluorescein
  • HY-117080
    Sulfo-EGS

    		Biochemical Assay Reagents Others
    Sulfo-EGS is a homobifunctional, amine-reactive chemical crosslinker. Sulfo-EGS is used to study protein-protein or protein-peptide interactions, which can determine the spatial proximity of amino acid residues in a protein complex, without relying on standards .
    Sulfo-EGS
  • HY-W749072
    BP Fluor 568 NHS ester

    		Fluorescent Dye Others
    BP Fluor 568 NHS ester is an amine-reactive, orange fluorescent dye routinely used to label proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules (Ex/Em: 578 nm/602 nm) .
    BP Fluor 568 NHS ester
  • HY-D1389
    Sulfo-CY-5.5 NHS ester tripotassium

    Sulfo-Cyanine5.5 NHS ester tripotassium

    		 Fluorescent Dye Others
    Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging .
    Sulfo-CY-5.5 NHS ester tripotassium
  • HY-15940
    5(6)-Carboxyfluorescein
    3 Publications Verification

    5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers

    		 Fluorescent Dye Cancer
    5(6)-Carboxyfluorescein (5(6)-FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5(6)-Carboxyfluorescein (5(6)-FAM) can be used to label proteins, peptides and nucleotides. 5(6)-Carboxyfluorescein can be used for the detection of tumour areas in vivo .
    5(6)-Carboxyfluorescein
  • HY-D2757
    5(6)-Carboxyrhodamine 110 NHS ester

    		Fluorescent Dye Others
    5(6)-Carboxyrhodamine 110 NHS Ester is the nonsulfonated analog of the BP Fluor 488 dye. The amine-reactive 5(6)-Carboxyrhodamine 110 NHS ester can be used to create bright and photostable green-fluorescent bioconjugates with excitation/emission maxima ~502/527 nm. The conjugates of this dye often used for Fluorescence Correlation Spectroscopy (FCS).
    5(6)-Carboxyrhodamine 110 NHS ester
  • HY-110210
    BODIPY-FL NHS ester

    BODIPY FL,SE

    		 Fluorescent Dye Others
    BODIPY FL NHS ester (BODIPY FL, SE) is a cell membranes-penatrable amine-reactive fluorescent probe. The maximum excitation/emission wavelength of the BODIPY-FL NHS ester are 502/511 nm, respectively. BODIPY-FL NHS ester has high stability and is insensitive to the polarity, pH and type of solvent, and can maintain stable fluorescence properties under different environmental conditions. BODIPY-FL NHS ester can be used for the synthesis of protease substrates, live cell imaging, protein labeling and immunoassay .
    BODIPY-FL NHS ester
  • HY-W800839
    TCO-PEG4-TFP ester

    		Biochemical Assay Reagents Others
    TCO-PEG4-TFP Ester is an amine-reactive labeling reagent used to modify proteins, antibodies, and other amine-containing biopolymers. A 2,3,5,6-tetrafluorophenol (TFP) is a reactive ester that displays much better stability toward hydrolysis in aqueous media resulting in more efficiency and better reproducible labeling of biopolymers. TFP ester of carboxylic acids react with primary amines at the same rate as NHS ester forming covalent amide bond that is identical to one formed by the reaction between primary amines and NHS esters or sulfo-NHS esters.
    TCO-PEG4-TFP ester
  • HY-15941
    5(6)-FITC
    2 Publications Verification

    Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers

    		 Fluorescent Dye Others
    5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of a fluorescent dye, characterized by high absorbance and excellent fluorescence quantum yield. The isothiocyanate group of FITC can react with various functional groups on proteins, including amines, thiols, imidazoles, tyrosines and carbonyls, enabling the labeling of proteins such as antibodies and lectins. 5(6)-FITC has a wide range of applications, including flow cytometry, immunofluorescence, protease assays and conjugation. The maximum excitation/emission wavelengths are 492/518 nm .
    5(6)-FITC
  • HY-W591390
    6-Azidohexanoic acid STP ester

    		Biochemical Assay Reagents Others
    6-Azidohexanoic Acid STP Ester is an amine-reactive, water-soluble labeling reagent with an azide group and a terminal 4-Sulfo-2,3,5,6-tetrafluorophenyl (STP) group. 6-Azidohexanoic Acid STP Ester is used to modify proteins, antibodies, and other amine-containing biopolymers in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. STP esters can react with primary amines, forming covalent amide bonds, and typically display much better stability toward hydrolysis in aqueous media, resulting in more efficiency and better reproducible labeling of biopolymers.
    6-Azidohexanoic acid STP ester
  • HY-172728
    Difluorocarboxyfluorescein NHS Ester, 6-isomer

    		Fluorescent Dye Others
    Difluorocarboxyfluorescein NHS Ester, 6-isomer is an amine-reactive fluorinated analog of fluorescein that overcomes some of the key limitations of fluorescein, including greater photostability and a lower pKa (pKa ~ 4.7 versus 6.4 for fluorescein), making its fluorescence essentially pH insensitive in the physiological pH range. Although the mixed isomers of Difluorocarboxyfluorescein NHS Ester, is a preferred, routinely used fluorescent dye for labeling proteins, peptides and nucleotides, purification of peptide and nucleotides labeled with 5(6) isomers might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer usually give better resolution in HPLC purification that is often required in the conjugation processes.
    Difluorocarboxyfluorescein NHS Ester, 6-isomer
  • HY-D1469
    5-Carboxyrhodamine 6G succinimidyl ester

    R6G-SE

    		 Fluorescent Dye Others
    5-Carboxyrhodamine 6G succinimidyl ester (R6G-SE) is an amine reactive fluorescent dye .
    5-Carboxyrhodamine 6G succinimidyl ester
  • HY-D1112
    TFAX 546,SE triethylammonium

    		Fluorescent Dye Others
    TFAX 546,SE triethylammonium, an amine reactive yellow fluorescent dye, can forms bright and photostable conjugates with proteins and antibodies .
    TFAX 546,SE triethylammonium
  • HY-W800726
    BB1-NHS ester

    		Biochemical Assay Reagents Others
    BB1-NHS ester is amine reactive at pH 7-9 to form a stable, irreversible amide bond. It was used in a unique chemselective "unclickable' bioconjugation strategy to site specifically modify proteins.
    BB1-NHS ester
  • HY-D2773
    5-Carboxyrhodamine 110 NHS ester

    		Fluorescent Dye Others
    5-Carboxyrhodamine 110 NHS Ester is the nonsulfonated analog of the BP Fluor 488 dye. The amine-reactive 5(6)-Carboxyrhodamine 110 NHS Ester can be used to create bright and photostable green-fluorescent bioconjugates with excitation/emission maxima ~502/527 nm. For many applications, the dye is preferred over 5-(6)-carboxyfluorescein NHS ester or FITC because of its exceptional photostability and fluorescence insensitivity to pH (4-9). Although the mixed isomers of Carboxyrhodamine 110 NHS Ester preferred, routinely used fluorescent dye for labeling proteins, peptides and nucleotides, purification of peptide and nucleotides labeled with 5(6) isomers might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer usually give better resolution in HPLC purification that is often required in the conjugation processes.
    5-Carboxyrhodamine 110 NHS ester
  • HY-169754
    BP Fluor 350 NHS ester

    		Fluorescent Dye Others
    BP Fluor 350 NHS ester is an amine reactive, water soluble, blue emitting dye used to specifically and efficiently modify primary amines at pH 7-9 to form stable covalent amide bonds .
    BP Fluor 350 NHS ester
  • HY-W441013
    DSPE-PEG-NHS, MW 1000

    		Liposome Others
    DSPE-PEG-NHS, MW 1000 is an amine reactive phospholipid. The reaction between NHS esters and amines forms a stable amide bond. The polymer is amphiphilic and capable of forming micelles or lipid bilayer in aqueous solution.
    DSPE-PEG-NHS, MW 1000
  • HY-D2736
    BP Light 800 NHS ester

    		Fluorescent Dye Others
    BP Light 800 NHS ester is an amine reactive hydrophilic fluorochrome . It can be conjugated to antibody with higher D/P ratio and widely used applications including western blotting, microscopy, flow cytometry, and cell based assays.
    BP Light 800 NHS ester
  • HY-D0049
    6-TAMRA-SE
    1 Publications Verification

    6-TAMRA-NHS ester; 6-Carboxytetramethylrhodamine N-succinimidyl ester

    		 DNA Stain Others
    6-TAMRA-SE (6-TAMRA-NHS ester) is a fluorescent dye carrying the amine reactive group. 6-TAMRA-SE is one of the traditional fluorophores used for automated DNA sequencing .
    6-TAMRA-SE
  • HY-W800711
    SPDP-Gly-Pro-NHS ester

    		Biochemical Assay Reagents Others
    SPDP-Gly-Pro-NHS ester is a linker with SPDP and NHS ester moieties. The SPDP is an amine and thiol reactive crosslinker. It is also membrane permeable, allowing it to participate in intracellular crosslinking reactions. The NHS ester is amine reactive and forms stable amide bonds.
    SPDP-Gly-Pro-NHS ester
  • HY-151698
    TCO-NHS Ester (axial)

    		ADC Linker Others
    TCO-NHS Ester axial is a click chemistry reagent that can be used as a building block in amine reactions. TCO-NHS Ester axial contains TCO groups, which can undergo inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
    TCO-NHS Ester (axial)
  • HY-D1662
    BDP 558/568 NHS ester

    BODIPY 558/568SE

    		 Fluorescent Dye Others
    BDP 558/568 NHS ester is a borondipyrromethene fluorophore with emission in the yellow part of the spectrum. BDP 558/568 NHS ester is an amine reactive NHS ester, and the absorption and emission spectra of BDP 558/568 NHS ester are similar with TAMRA, BDP TMR, Cyanine3, and sulfo-Cyanine3 .
    BDP 558/568 NHS ester
  • HY-W451405
    2,5-Dioxopyrrolidin-1-yl hept-6-ynoate

    		Biochemical Assay Reagents Others
    2,5-Dioxopyrrolidin-1-yl hept-6-ynoate is an amine reactive four carbon reagent that can be used for derivatizing peptides, antibodies, amine coated surfaces etc. The alkyne group reacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions.
    2,5-Dioxopyrrolidin-1-yl hept-6-ynoate
  • HY-D2761
    DY-680-NHS ester

    		Fluorescent Dye Others
    DY-680-NHS ester is an amine reactive hydrophilic fluorochrome. It can be conjugated to an antibody with higher D/P ratio without causing fluorescence quenching and conjugate precipitation, and it is widely used in applications including western blotting, microscopy, flow cytometry, and cell-based assays. The spectrum has an excitation of 690nm and emission at 709nm.
    DY-680-NHS ester
  • HY-D1635
    Sulfo-NHS-LC-LC-Biotin

    Biotin-XX-SSE

    		 Fluorescent Dye Infection
    Sulfo-NHS-LC-LC-Biotin (Biotin-XX-SSE), a biotin reagent, is used to label the proteins exposed to the external leaflet of intact exosomes and contains a larger spacer arm between the biotin and amine reactive linker. The size of this linker helps to overcome steric hindrance and increases labeling efficiency at the crowded exosome surface .
    Sulfo-NHS-LC-LC-Biotin
  • HY-W190950
    AZD-PEG5-PFP

    		Biochemical Assay Reagents Others
    AZD-PEG5-PFP is a PEG linker containing an AZD group and a PFP ester group, an activated ester that reacts with primary amines to form amide bonds. PFP ester has been found to be more stable than other amine reactive groups because it is less likely to undergo hydrolysis. The hydrophilic PEG spacer increases solubility in aqueous media.
    AZD-PEG5-PFP
  • HY-W800610
    AZD-PEG13-PFP

    		Biochemical Assay Reagents Others
    AZD-PEG13-PFP is a PEG linker containing an AZD group and a PFP ester group, an activated ester that reacts with primary amines to form amide bonds. PFP ester has been found to be more stable than other amine reactive groups because it is less likely to undergo hydrolysis. The hydrophilic PEG spacer increases solubility in aqueous media.
    AZD-PEG13-PFP
  • HY-W190933
    Bis-PEG6-TFP ester

    		Biochemical Assay Reagents Others
    Bis-PEG6-TFP ester is a PEG linker with two terminal TFP ester moieties. TFP esters are amine reactive and are also more stable than NHS esters against hydrolysis. The PEG chain increases the water solubility properties of compounds in aqueous media. The water solubility properties of PEG chains are enhanced as the PEG chain grows.
    Bis-PEG6-TFP ester
  • HY-W451460
    2,5-Dioxopyrrolidin-1-yl 2-(prop-2-yn-1-yloxy)acetate

    		Biochemical Assay Reagents Others
    2,5-Dioxopyrrolidin-1-yl 2-(prop-2-yn-1-yloxy)acetate is a Click Chemistry reagent with a propargyl group and an NHS ester group. The propargyl group can react with biomolecules containing azide group via copper catalyzed Click Chemistry reaction. The NHS ester is an amine reactive group which can be used for derivatizing peptides, antibodies, amine coated surfaces, etc.
    2,5-Dioxopyrrolidin-1-yl 2-(prop-2-yn-1-yloxy)acetate
  • HY-D2738
    BP Fluor 532 NHS ester

    		Fluorescent Dye Others
    BP Fluor 532 NHS ester is an amine reactive, yellow-emitting dye routinely used to label proteins or antibodies through primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond. BP Fluor 532 is a bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.
    BP Fluor 532 NHS ester

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