2. Academic Validation
  3. Eco-friendly synthesis and biological evaluation of substituted pyrano[2,3-c]pyrazoles

Eco-friendly synthesis and biological evaluation of substituted pyrano[2,3-c]pyrazoles

  • Bioorg Med Chem Lett. 2012 Aug 15;22(16):5272-8. doi: 10.1016/j.bmcl.2012.06.055.
Santhosh Reddy Mandha 1,  Sravanthi Siliveri,  Manjula Alla,  Vittal Rao Bommena,  Madhava Reddy Bommineni,  Sridhar Balasubramanian
Affiliations

Affiliation

  • 1 Crop Protection Chemicals Division, Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500607, India.
PMID: 22818081 DOI: 10.1016/j.bmcl.2012.06.055
Abstract

An ecofriendly green approach for synthesis of substituted pyrano[2,3-c]pyrazoles has been developed via a multicomponent one pot approach in aqueous ethanol medium under totally non-catalytic conditions. The synthesized compounds were evaluated for their Antibacterial, anti-inflammatory and cytotoxic activities.

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