2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.

Liposome Related Products (729):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-141614
    1,2-Diarachidoyl-sn-glycero-3-phosphocholine
    1,2-Diarachidoyl-sn-glycero-3-phosphocholine (1,2-DAPC) is a phospholipid containing the saturated long-chain (20:0) arachidic acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
    1,2-Diarachidoyl-sn-glycero-3-phosphocholine
  • HY-115435
    1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium
    		≥98.0%
    1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium is an anionic phospholipid with myristic acid tails (14:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of liposome.
    1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium
  • HY-169484
    SIL lipid
    SIL lipid is the synthetic ionized lipid, and can be used for synthesis of lipid nanoparticles (LNPs) for siRNA delivery.
    SIL lipid
  • HY-172016
    CP-LC-0867
    CP-LC-0867 is an ionizable cationic amino lipid efficient delivery of different kinds of RNA (mRNA, cRNA and saRNA).
    CP-LC-0867
  • HY-W704076
    Glyceryl monostearate-d5
    Glyceryl monostearate-d5 (GMS-d5) is deuterium labeled Glyceryl monostearate. Glyceryl monostearate (GMS) is a single-tailed lipidic monoglyceride that can be used to synthesize nanoliposomes for drug delivery.
    Glyceryl monostearate-d<sub>5</sub>
  • HY-141629S2
    N-Palmitoyl-D-sphingomyelin-d9
    N-Palmitoyl-D-sphingomyelin-d9 (Sphingomyelin 16:0-d9) is deuterium labeled N-Palmitoyl-D-sphingomyelin. N-Palmitoyl-D-sphingomyelin (Sphingomyelin 16:0) (Compound SM-03) can be used for the synthesis of lipid nanoparticles.
    N-Palmitoyl-D-sphingomyelin-d<sub>9</sub>
  • HY-158146
    sGC activator 1
    sGC activator 1 (example 10B) is an activator of soluble guanylate cyclase (SGC).
    sGC activator 1
  • HY-160554
    C12-113
    C12-113 is a lipidoid delivery agent that can be used to transfect siRNA into cells. C12-113 can also be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of mRNA encoding the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice.
    C12-113
  • HY-W441006
    DSPE-glutaric acid
    DSPE-glutaric acid is a lipid. DSPE-glutaric acid can be used for the research of various biochemical.
    DSPE-glutaric acid
  • HY-W440917
    DSPE-PEG-FITC (MW 5000)
    DSPE-PEG-FITC, MW 5000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
    DSPE-PEG-FITC (MW 5000)
  • HY-W440940
    Stearic acid-PEG-FITC, MW 5000
    Stearic acid-PEG-FITC, MW 5000 is a PEG lipid which forms micelles in water and can be used for drug delivery applications. The FITC fluorescent can be easily traced by miscroscopy. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
    Stearic acid-PEG-FITC, MW 5000
  • HY-145507
    1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium)
    1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (16:0 Lyso PE) sodium is a lysophospholipid containing palmitic acid (16:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
    1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium)
  • HY-145506
    1-Stearoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium)
    1-Stearoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (18:0 Lyso PE) sodium is a lysophospholipid containing stearic acid (18:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
    1-Stearoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium)
  • HY-W800783
    DSTAP chloride
    DSTAP chloride (CDESA) is a cationic lipid that used in the formation of lipid nanoparticles (LNPs). DORI chloride has high transfection efficiency.
    DSTAP chloride
  • HY-169480
    Lipid C2
    Lipid C2 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNP) for mRNA delivery in vivo. LNPs containing Lipid C2 and encapsulating an mRNA reporter selectively accumulate in the liver and spleen but not the heart, lungs, or kidneys in mice. LNP containing Lipid C2 and encapsulating mRNA encoding the Epstein-Barr virus (EBV) protein latent membrane protein 2 (LMP-2), in combination with an anti-programmed cell death protein 1 (PD-1) antibody, decrease tumor volume and reverse T cell exhaustion, as well as increase the percentage of CD3+CD8+ central and CD3+CD8+ effector memory T cells and decrease the percentage of CD3+ T cells expressing Pd-1, in the spleen in a CT26 murine EBV-infected colon cancer model.
    Lipid C2
  • HY-W339834
    1-Stearoyl-sn-glycerol 3-phosphate sodium
    1-Stearoyl-sn-glycerol 3-phosphate sodium is a bioactive phospholipid that plays a crucial role in modulating cellular processes such as motility, proliferation, invasion, survival, and growth factor production, primarily through its interaction with G protein-coupled receptors (GPCRs). Typically found at low concentrations in plasma (~100nM), this compound is synthesized during the formation of membrane phospholipids and is derived from various cell types, including activated platelets, epithelial cells, leukocytes, neuronal cells, and tumor cells. Its unique structure includes stearic acid at the sn-1 position alongside a hydroxyl group at the sn-2 position.
    1-Stearoyl-sn-glycerol 3-phosphate sodium
  • HY-142992
    LNP Lipid-2
    LNP Lipid-2 is a lipid product can be used to deliver agents.
    LNP Lipid-2
  • HY-160578
    Glucosamine Cholesterol
    Glucosamine Cholesterol (N-Cholesteryl succinyl glucosamine) is a glucosamine-based lipid conjugate, and can be used in the formation of lipid nanoparticles (LNPs).
    Glucosamine Cholesterol
  • HY-160257
    DOPE-PEG-BDP FL,MW 5000
    DOPE-PEG-BDP FL,MW 5000 is a PEG-lipid-dye conjugate consists of a DOPE phospholipid which is an unsaturated phospholipid, a BDP FL fluorophore with featuring excitation and emission maxima at 504 and 514 nm respectively and a large PEG spacer which links the former substance together.
    DOPE-PEG-BDP FL,MW 5000
  • HY-169478
    Lipid N2-3L
    Lipid N2-3L is an ionizable cationic lipid (pKa = 8.99) that can be used to generate supramolecular lipid nanoparticles (SMLNPs) for mRNA delivery. Lipid nanoparticles formed by encapsulating a luciferase reporter gene with Lipid N2-3L were detected to accumulate in the lymph nodes of mice, indicating that they can effectively enter the mouse immune system. Lipid nanoparticles formed by encapsulating ovalbumin mRNA and the TLR7/8 agonist Resiquimod (HY-13740) with Lipid N2-3L were able to reduce tumor volume and increase survival in the MC-38-OVA mouse colon cancer model. Lipid N2-3L can be used in the research of drug delivery for cancer-related therapies.
    Lipid N2-3L