2. Signaling Pathways
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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1337):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-145673
    Thiamphenicol glycinate
    Thiamphenicol glycinate, an alpha-amino acid ester, is a proagent of Thiamphenicol (HY-B0479).
    Thiamphenicol glycinate
  • HY-E70242
    3-Ketohexanoyl-CoA
    3-Ketohexanoyl-CoA is a derivative of coenzyme A containing a ketone group.
    3-Ketohexanoyl-CoA
  • HY-133601
    3,4,5-Trichloroguaiacol
    3,4,5-Trichloroguaiacol is a phenolic compound occurring in effluents from bleached kraft pulp mills.
    3,4,5-Trichloroguaiacol
  • HY-129932
    Pyrrolidine ricinoleamide
    Pyrrolidine ricinoleamide ((R)-5d) is a fatty acid amide that exhibits effective antiproliferative activity against a series of cancer cells, including human glioma U251 cells. Pyrrolidine ricinoleamide can be used in cancer research.
    Pyrrolidine ricinoleamide
  • HY-N2287
    Cimifugin 4'-O-β-D-glucopyranoside
    Cimifugin 4'-O-β-D-glucopyranoside is a derivative of cimifugin.
    Cimifugin 4'-O-β-D-glucopyranoside
  • HY-130487
    miR-21-IN-2
    miR-21-IN-2 is an active compound.
    miR-21-IN-2
  • HY-130229
    (±)5,6-DHET lactone
    5,6-DiHET lactone ((±)5,6-DiHETrE lactone) is a lactonized form of 5,6-EET and 5,6-DiHET. In solution, 5(6)-EET degrades into 5(6)-DiHET and 5(6)-δ-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS.1 5,6-DiHET potently induces vasodilation of isolated canine coronary arterioles, with 41 and 100% inhibition occurring at 0.01 and 100 pM, respectively. It also induces vasodilation in isolated human microvessels and increases intracellular calcium levels in a dose-dependent manner, an effect that can be blocked by the nitric oxide scavenger L-NAME.
    (±)5,6-DHET lactone
  • HY-111131
    RY764
    RY764 is an active compound.
    RY764
  • HY-126733
    (6R)-Leucovorin
    (6R)-Leucovorin is a derivative of Folic Acid, a vitamin that plays a crucial role in DNA synthesis, DNA repair, and DNA methylation, and also serves as a cofactor in biological reactions involving folate.
    (6R)-Leucovorin
  • HY-122351
    Advantame free acid
    Advantame is an N-substituted aspartame derivative and acts as a non-caloric artificial sweetener.
    Advantame free acid
  • HY-W224855
    WAY-634964
    		≥98.0%
    WAY-634964 is an active molecule.
    WAY-634964
  • HY-19585
    Enloplatin
    Enloplatin is a carboplatin analog, and can be used for study of ovarian cancer.
    Enloplatin
  • HY-W004292R
    1-Undecanol (Standard)
    1-Undecanol (Standard) (Undecyl alcohol (Standard)) is an analytical reference standard for 1-Undecanol (HY-W004292). This product is used for research and analytical applications. 1-Undecanol (Undecyl alcohol) is the main product generated from the degradation of 2-tridecanone by Pseudomonas bacteria isolated from the soil. 1-Undecanol can enhance the attraction of Grapholita molesta to sex pheromone traps.
    1-Undecanol (Standard)
  • HY-123327
    FAUC-113
    FAUC-113 is an active compound.
    FAUC-113
  • HY-116464
    4-APB hydrochloride
    4-APB hydrochloride is a benzofuran.
    4-APB hydrochloride
  • HY-113717
    ICL-SIRT078
    ICL-SIRT078 is an active compound.
    ICL-SIRT078
  • HY-118842
    Sunepitron hydrochloride
    Sunepitron (CP-93,393) hydrochloride is a potent anxiolytic/antidepressantcan agent.
    Sunepitron hydrochloride
  • HY-19590
    Etarotene
    Etarotene (Ro 15-1570) is a derivative of Arotinoid (HY-106735). Etarotene is an orally active antitumor agent against DMBA (HY-W011845)-induced mammary tumor and causes toxic symptoms of hypervitaminosis A in rat model.
    Etarotene
  • HY-169500
    Mitomycin Z
    Mitomycin Z (9a-O-Demethylmitomycin G) is a member of the mitomycin family with an antitumor activity.
    Mitomycin Z
  • HY-P10490
    (D-His(Bzl)6)-LHRH (1-7) free acid
    (D-His(Bzl)6)-LHRH (1-7) free acid is a synthetic peptide compound that is a derivative of luteinizing hormone-releasing hormone (LHRH). (D-His(Bzl)6)-LHRH (1-7) free acid enhances its stability and biological activity by introducing unnatural amino acid residues at specific positions of the LHRH molecule. This modification can improve the drug's performance in the body half-life, reducing the rate at which it is rapidly metabolized and cleared, thereby enhancing its efficacy in inhibiting cell proliferation.
    (D-His(Bzl)6)-LHRH (1-7) free acid