2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (7645):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W145584S
    D-Iditol-13C
    D-Iditol-13C is the 13C labeled D-Iditol. D-Iditol is a fungal metabolite, a sugar alcohol that accumulates in galactokinase deficiency. D-Iditol may have potential antitumour activity[1][2][3].
    D-Iditol-<sup>13</sup>C
  • HY-W015812S
    2,3,5-Trimethylphenol-d11
    2,3,5-Trimethylphenol-d11 is the deuterium labeled 2,3,5-Trimethylphenol[1].
    2,3,5-Trimethylphenol-d<sub>11</sub>
  • HY-B0280S1
    Ranolazine-d8
    		99.83%
    Ranolazine-d8 is the deuterium labeled Ranolazine. Ranolazine (CVT 303) is an anti-angina agent that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP)[1][2]. Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor[3]. Antianginal agent.
    Ranolazine-d<sub>8</sub>
  • HY-114041S
    Resolvin E1-d4
    Resolvin E1-d4 (RvE1-d4) is deuterium labeled Resolvin E1. Resolvin E1 (RvE1), a potent endogenous pro-resolving mediator of inflammation, is derived from omega-3 fatty acid eicosapentaenoic acid (EPA). Resolvin E1 is endogenously biosynthesized from EPA in the presence of Aspirin during the spontaneous resolution phase of acute inflammation, where specific cell-cell interactions occur. Resolvin E1 possesses unique counterregulatory actions that inhibit polymorphonuclear leukocyte (PMN) transendothelial migration. Resolvin E1 also acts as a potent inhibitor of leukocyte infiltration, dendritic cell migration, and IL-12 production.
    Resolvin E1-d<sub>4</sub>
  • HY-N0465S
    Olaquindox-d4
    Olaquindox-d4 is the deuterium labeled Olaquindox (HY-N0465). Olaquindox, a quinoxalin derivative, is an orally active antibiotic. Olaquindox stimulates growth and decreases intestinal mucosal immunity of piglets.
    Olaquindox-d<sub>4</sub>
  • HY-B1319S1
    Pramocaine-d9 hydrochloride
    Pramocaine-d9 (hydrochloride) is deuterium labeled Pramocaine (hydrochloride). Pramocaine hydrochloride decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses.
    Pramocaine-d<sub>9</sub> hydrochloride
  • HY-B0002BS2
    Ondansetron-13C,d3
    Ondansetron-13C,d3 is the 13C- and deuterium labeled Ondansetron[1].
    Ondansetron-<sup>13</sup>C,d<sub>3</sub>
  • HY-100064S1
    O-Desmethyl gefitinib-d6
    O-Desmethyl gefitinib-d6 is the deuterium labeled O-Desmethyl gefitinib. O-Desmethyl gefitinib is an active metabolite of Gefitinib in human plasma. The formation of O-desmethyl gefitinib is dependent on CYP2D6 activity. O-desmethyl gefitinib inhibits EGFR with an IC50 of 36 nM in subcellular assays[1][2].
    O-Desmethyl gefitinib-d<sub>6</sub>
  • HY-146647S
    Cholesta-3,5-diene-7-one-25,26,26,26,27,27,27-d7
    Cholesta-3,5-diene-7-one-25,26,26,26,27,27,27-d7 is the deuterium labeled Cholesta-3,5-diene-7-one-25,26,26,26,27,27,27[1].
    Cholesta-3,5-diene-7-one-25,26,26,26,27,27,27-d<sub>7</sub>
  • HY-119788S
    Fenitrothion oxon-d6
    Fenitrothion oxon-d6 is the deuterium labeled Fenitrothion oxon[1].
    Fenitrothion oxon-d<sub>6</sub>
  • HY-W042416S2
    N,N-Dimethylacetamide-d3
    N,N-Dimethylacetamide-d3 is the deuterium labeled N,N-Dimethylacetamide[1]. N,N-Dimethylacetamide (DMAc) is an inexpensive, common aprotic organic solvent[2].
    N,N-Dimethylacetamide-d<sub>3</sub>
  • HY-14268S1
    Febuxostat-d7
    Febuxostat-d7 is deuterium labeled Febuxostat. Febuxostat (TEI 6720) is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1].
    Febuxostat-d<sub>7</sub>
  • HY-144155S1
    5-Hydroxy Rosiglitazone-d4-1
    5-Hydroxy Rosiglitazone-d4-1 is the deuterium labeled 5-Hydroxy Rosiglitazone[1].
    5-Hydroxy Rosiglitazone-d<sub>4</sub>-1
  • HY-120356S1
    T-1101-d7
    T-1101-d7 is the deuterium labeled T-1101[1].
    T-1101-d<sub>7</sub>
  • HY-17007S
    Saquinavir-d9
    Saquinavir-d9 (Ro 31-8959-d9) is the deuterium labeled Saquinavir (HY-17007). Saquinavir (Ro 31-8959) is an orally active HIV protease inhibitor that can be used in the research of AIDS. Saquinavir also has anti-inflammatory activity and can induce apoptosis of human red blood cells.
    Saquinavir-d<sub>9</sub>
  • HY-N6746S1
    Citrinin-13C13
    Citrinin-13C13 (NSC 186-13C13) is the 13C labeled Citrinin (HY-N6746). Citrinin (NSC 186) is a mycotoxin that causes food contamination and has different toxic effects. Citrinin is an effective oral anticancer agent. Citrinin has various regulatory effects on mouse immune system, including regulating the number of immune cells, inducing apoptosis and autophagy of immune cells, altering toll-like receptor expression and cytokine production. Citrinin can induce oxidative stress and lead to early apoptosis of oocytes. Low doses of Citrinin have neuroprotective effects against glutamate-induced excitotoxicity in rat cortical neurons. In addition, Citrinin also has antibacterial activity.
    Citrinin-<sup>13</sup>C<sub>13
  • HY-136648S2
    2'-Deoxyadenosine-5'-triphosphate-15N5,d14 dilithium
    2'-Deoxyadenosine-5'-triphosphate-15N5,d14 (dATP-15N5,d14) dilithium is deuterium and 15N labeled 2'-Deoxyadenosine-5'-triphosphate (HY-136648). 2'-Deoxyadenosine-5'-triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase.
    2'-Deoxyadenosine-5'-triphosphate-<sup>15</sup>N<sub>5</sub>,d<sub>14</sub> dilithium
  • HY-14281S2
    Trilostane-d3-1
    Trilostane-d3-1 (Win 24540-d3-1) is deuterium-labeled Trilostane (HY-14281).
    Trilostane-d<sub>3</sub>-1
  • HY-59137S1
    1-Methyl-imidazole-d3
    1-Methyl-imidazole-d3 is the deuterium labeled 1-Methylimidazole[1].
    1-Methyl-imidazole-d<sub>3</sub>
  • HY-W010807S
    Hexadecyl palmitate-d3
    Hexadecyl palmitate-d3 is the deuterium labeled Hexadecyl palmitate.
    Hexadecyl palmitate-d<sub>3</sub>