2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1337):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-129865
    MET oxalate
    MET oxalate is s a tryptamine.
    MET oxalate
  • HY-W181871
    Piperidione
    Piperidione is a cough agent.
    Piperidione
  • HY-135448
    25G-NBOMe hydrochloride
    25G-NBOMe hydrochloride is a derivative of 2,5-phenethylamines, characterized by the addition of a benzyl-methoxy (BOMe) group to the amine.
    25G-NBOMe hydrochloride
  • HY-N10337
    Norjuziphine
    Norjuziphine is an alkaloid found in the lotus flower (Nelumbo nucifera). Norjuziphine inhibits the melanogenesis of murine B16 melanoma 4A5 cells stimulated by Theophylline (HY-B0809) (IC50=14.4 μM). Norjuziphine is promising for research of skin whitening and related skin pigmentation diseases.
    Norjuziphine
  • HY-W364575
    Methyl-4-oxoretinoate
    Methyl-4-oxoretinoate is a derivative of Retinoic acid (HY-14649). Methyl-4-oxoretinoate inhibits TPA (HY-18739)-induced ornithine decarboxylase (ODC) activity, and carcinogen-induced papillomas in mouse skin.
    Methyl-4-oxoretinoate
  • HY-N15182
    4-Trehalosamine
    4-Trehalosamine is a derivative of trehalose with weak antibacterial activity. 4-Trehalosamine shows no toxic effects when injected intravenously into mice at a dose of 625 mg/kg.
    4-Trehalosamine
  • HY-W719011
    N-Propyl buphedrone hydrochloride
    		Control
    N-Propyl buphedrone hydrochloride is a cathinone.
    N-Propyl buphedrone hydrochloride
  • HY-138873
    (±)-Threo-Isopropylphenidate hydrochloride
    (±)-Threo-Isopropylphenidate hydrochloride is structurally categorized as a phenethylamine.
    (±)-Threo-Isopropylphenidate hydrochloride
  • HY-W188178
    N-Mitrososarcosine
    N-Nitrososarcosine is a nitrosation product of Sarcosine (HY-101037) and can be found in cured meat products. N-Nitrososarcosine (225 mg/kg) induces the formation of metastatic liver carcinomas in mice.
    N-Mitrososarcosine
  • HY-49457
    Copper(II) ionophore I
    Copper(II) ionophore I is a neutral Cu+ ionophore.
    Copper(II) ionophore I
  • HY-157856
    rel-4(5)-Epdpe methyl ester
    rel-4(5)-Epdpe methyl ester is a rel-4(5)-Epdpe derivative.
    rel-4(5)-Epdpe methyl ester
  • HY-W715084
    2-Chloroethcathinone hydrochloride
    		Control
    2-Chloroethcathinone hydrochloride is structurally categorized as a cathinone.
    2-Chloroethcathinone hydrochloride
  • HY-B1045
    Chlorazanil hydrochloride
    Chlorazanil hydrochloride is an orally effective diuretic.
    Chlorazanil hydrochloride
  • HY-161088
    Anti-aging agent 1
    Anti-aging agent 1 (compound 24) is a derivative of piperlongumine (HY-N2329) (PL). Anti-aging agent 1 exhibits a 50-fold enhancement in senolytic activity against senescent WI-38 fibroblasts compared to PL.
    Anti-aging agent 1
  • HY-135076
    2,3-Dimethylmethcathinone hydrochloride
    2,3-Dimethylmethcathinone hydrochloride is a cathinone analog.
    2,3-Dimethylmethcathinone hydrochloride
  • HY-W281950
    2-(Carbamimidoylsulfanyl)acetic acid hydrochloride
    2-(Carbamimidoylsulfanyl)acetic acid hydrochloride is a thiourea compound and an Isothiourea derivative, with potential antidiabetic activity.
    2-(Carbamimidoylsulfanyl)acetic acid hydrochloride
  • HY-168812
    3,4-Methylenedioxy-α-pyrrolidinoisohexanophenone hydrochloride
    3,4-Methylenedioxy-α-pyrrolidinoisohexanophenone hydrochloride is a cathinone.
    3,4-Methylenedioxy-α-pyrrolidinoisohexanophenone hydrochloride
  • HY-W725181
    Methyl 2-phenyl-2-(pyrrolidin-1-yl)acetate hydrochloride
    		Control
    Methyl 2-phenyl-2-(pyrrolidin-1-yl)acetate hydrochloride is structurally similar to known stimulants.
    Methyl 2-phenyl-2-(pyrrolidin-1-yl)acetate hydrochloride
  • HY-W190972
    3-(3-Nitrophenyl)-5-phenyl-1,2,4-oxadiazole
    3-(3-Nitrophenyl)-5-phenyl-1,2,4-oxadiazole is a PEG derivative containing a tert-butyl ester and an azide group.
    3-(3-Nitrophenyl)-5-phenyl-1,2,4-oxadiazole
  • HY-170717
    3-Methylnordiazepam
    3-Methylnordiazepam (RO-5-2751) is a benzodiazepine and shows anticonvulsant activity in mice.
    3-Methylnordiazepam