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  3. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1337):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-161648
    Anticancer agent 222
    Anticancer agent 222 (Compound 19) is an orally active anticancer agent that exhibits significant anticancer activity against Huh7, FOCUS, SNU475, SNU182, HepG2, and Hep3B cells (IC50 = 2.9–9.3 μM).
    Anticancer agent 222
  • HY-15189
    17-Aminogeldanamycin
    17-Aminogeldanamycin is an active compound.
    17-Aminogeldanamycin
  • HY-107714
    MNI-D-aspartate
    MNI-D-aspartate is an active compound.
    MNI-D-aspartate
  • HY-12690
    DOTA derivative
    DOTA derivative is a cyclic tosamide benzylic derivative.
    DOTA derivative
  • HY-W009004
    Trilysine
    Trilysine is sourced from L-lysine .
    Trilysine
  • HY-19040
    Ro 16-8714
    Ro 16-8714 is an active compound.
    Ro 16-8714
  • HY-148154
    Poly(oxy-1,2-ethanediyl)-propoxy-amide-C6
    Poly(oxy-1,2-ethanediyl)-propoxy-amide-C6 (n=450) is an active compound. Poly(oxy-1,2-ethanediyl)-propoxy-amide-C6 is a small molecule moiety for pegylation modification in Avacincaptad pegol (HY-147080).
    Poly(oxy-1,2-ethanediyl)-propoxy-amide-C6
  • HY-137211
    Hydrocortisone-21-lysinate
    Hydrocortisone-21-lysinate is an active compound.
    Hydrocortisone-21-lysinate
  • HY-118583A
    4-Fluoro phenibut hydrochloride
    4-Fluoro phenibut (β-(4-Fluorophenyl)-GABA) hydrochloride is a Gabapentinoid and is structurally similar to known nootropics.
    4-Fluoro phenibut hydrochloride
  • HY-111133
    LY 154045
    LY 154045 is an active compound.
    LY 154045
  • HY-B1708
    Nordefrin
    Nordefrin ((±)-Cobefri), a Norepinephrine (HY-13715) derivative, is a vasoconstrictor agent.
    Nordefrin
  • HY-145503
    Decanoyl-L-carnitine chloride
    Decanoyl-L-carnitine chloride is an ester derivative of L-carnitine, which is an important cofactor of fatty acid metabolism.
    Decanoyl-L-carnitine chloride
  • HY-119336
    Mebroqualone
    Mebroqualone is structurally categorized as a quinazolinone.
    Mebroqualone
  • HY-P10920
    DOTAMTATE
    DOTAMTATE is a somatostatin analogue. DOTAMTATE marked 212Pb is promising for research of somatostatin receptor positive neuroendocrine tumors.
    DOTAMTATE
  • HY-161845
    Anticancer agent 240
    Anticancer agent 240 (compound 9b) is an 8-quinolinesulfonamide derivative with a cytotoxicity activity. Anticancer agent 240 shows inhibitory activity in Caco-2, SNB-19, A-549, and SKOV-3 cell line IC50 values of 0.26, 0.38, 0.40 and 4.16 μM.
    Anticancer agent 240
  • HY-135202
    Chloromethylketone methotrexate
    Chloromethylketone methotrexate is an active compound.
    Chloromethylketone methotrexate
  • HY-124889
    Dimethenamid
    Dimethenamid is an active compound.
    Dimethenamid
  • HY-124288
    PDK1/AurA-IN-1
    PDK1/AurA-IN-1 is an active compound.
    PDK1/AurA-IN-1
  • HY-16394
    PG-11047 tetrahydrochloride
    ≥98.0%
    PG-11047 (CGC-11047), a polyamine analogue, is a nonfunctional competitor of the natural polyamine spermine. PG-11047 has broad spectrum anticancer activities.
    PG-11047 tetrahydrochloride
  • HY-122988
    Xenbucin
    Xenbucin is an active compound.
    Xenbucin