2. GPCR/G Protein Neuronal Signaling
  3. mGluR
  4. VU6010608

VU6010608 is a blood-brain barrier-crossing mGlu7 negative allosteric modulator (IC50 = 0.76 μM). VU6010608 can block long-term enhancement (LTP) of SC-CA1 synapses in mouse brain slices induced by high-frequency stimulation. VU6010608 can be used for research on neurological diseases.

For research use only. We do not sell to patients.

VU6010608

VU6010608 Chemical Structure

CAS No. : 2165325-42-6

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VU6010608 Related Antibodies

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Description

VU6010608 is a blood-brain barrier-crossing mGlu7 negative allosteric modulator (IC50 = 0.76 μM). VU6010608 can block long-term enhancement (LTP) of SC-CA1 synapses in mouse brain slices induced by high-frequency stimulation. VU6010608 can be used for research on neurological diseases[1].

Molecular Weight

408.33

Formula

C18H15F3N4O4
CAS No.
SMILES

O=C(NC1=CC(OC(F)(F)F)=CC=C1N2N=CN=C2)C3=CC=C(OC)C(OC)=C3
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Purity & Documentation
References
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VU6010608 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VU60106082165325-42-6VU 6010608VU-6010608mGluRMetabotropic glutamate receptorsInhibitorinhibitorinhibit

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