scavenger receptor

By Targets:	Scavenger Receptor Class B type I (SR-BI） (3) Apolipoprotein (1) Autophagy (1) Bacterial (1) Biochemical Assay Reagents (1) Fc Receptor (FcR) (1) HCV (3) Interleukin Related (1) LXR (1) NO Synthase (1) p38 MAPK (1) Reactive Oxygen Species (ROS) (1) Reference Standards (1) Sigma Receptor (2) TNF Receptor (1) Toll-like Receptor (TLR) (1) Transmembrane Glycoprotein (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (6) Infection (3) Inflammation/Immunology (5) Metabolic Disease (2)

Targets Recommended: Scavenger Receptor Class B type I (SR-BI）

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-19900

ITX5061 3 Publications Verification	p38 MAPK Autophagy HCV	Infection
ITX5061 is a type II inhibitor of p38 MAPK and also an antagonist of scavenger receptor B1 (SR-B1).

HY-B2087

Glycerol phenylbutyrate 1 Publications Verification HPN-100	Sigma Receptor	Cardiovascular Disease
Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand, with a pK_i of 8.02. Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger agent .

HY-P99529

Valziflocept BAX1810; TAK-752	Fc Receptor (FcR)	Inflammation/Immunology
Valziflocept (BAX1810; TAK-752) is a recombinant soluble human FcγRIIb receptor that targets Fc and FcγR. FcγRs bind and neutralize pathogenic IgG, thus forming a "decoy" or "scavenger" receptor that can reduce the severity of autoimmune diseases. Valziflocept can be used in studies of autoimmune diseases such as systemic lupus erythematosus (SLE) .

HY-116767

BLT-1 5 Publications Verification Block lipid transport-1	HCV	Metabolic Disease Inflammation/Immunology
BLT-1, a thiosemicarbazone copper chelator, is a selective scavenger receptor B, type 1 (SR-BI) inhibitor. BLT-1 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. BLT-1 is a potent HCV entry inhibitor .

HY-119770

HDL376 SDZ-HDL 376	Scavenger Receptor Class B type I (SR-BI）	Cardiovascular Disease
HDL376 is a scavenger receptor class B type I (SR-BI) inhibitor. HDL376 directly inhibits SR-BI-mediated lipid transport in cells and in liposomes reconstituted with purified SR-BI (IC₅₀ = 0.22 μM). HDL376 can be used for the research of atherosclerotic coronary artery disease .

HY-124666

ML279	Scavenger Receptor Class B type I (SR-BI） HCV	Infection Cardiovascular Disease
ML279 is a potent scavenger receptor, class B, type I (SR-BI) inhibitor. ML279 can inhibit SR-BI-mediated lipid uptake by stabilizing the binding of HDL to SR-BI (EC₅₀ = 0.27 μM). ML279 can be used for the researches of infection and cardiovascular disease, such as atherosclerosis and HCV infection .

HY-154857

1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine	Scavenger Receptor Class B type I (SR-BI）	Cancer
1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine is a glycerophosphorylcholine, consisting of glycerol phosphate, choline and palmitic acid. It accumulates in vivo at sites of oxidative stress. 1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine may be a ligand of scavenger receptors class B, while oxidized phospholipids oxPC(CD36) are potent ligands of scavenger receptors class B (CD36 and SR-BI). Oxidized phospholipids (oxPLs) also play an important role in tumor apoptosis, may be elevated in malignant biliary strictures .

HY-139007

BLT-4	LXR	Metabolic Disease
BLT-4 is a specific, reversible inhibitor of scavenger receptor, class B, type I (SR-BI). BLT-4 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. .

HY-B2087R

Glycerol phenylbutyrate (Standard) HPN-100 (Standard)	Reference Standards Sigma Receptor	Cardiovascular Disease
Glycerol phenylbutyrate (Standard) is the analytical standard of Glycerol phenylbutyrate. This product is intended for research and analytical applications. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand, with a pK_i of 8.02. Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger agent .

HY-P11033

Pep2 Peptide	Transmembrane Glycoprotein	Cancer
Pep2 Peptide (also known as scavenger receptor B2) is a peptide ligand for the transmembrane glycoprotein CD36. Pep2 Peptide selectively binds to CD36 over HAS, IgG and CD44. Pep2 Peptide can be studied in research on enhancing delivery of anticancer agent .

HY-NP203

High density lipoprotein (human) HDL (human)	Apolipoprotein NO Synthase	Cardiovascular Disease
High density lipoprotein (HDL) (human) is a functional lipoprotein that binds to receptors such as scavenger receptor B1 (SR-B1), ABCA1 and ABCG1. High density lipoprotein (human) clears excess cholesterol from peripheral tissues through reverse cholesterol transport (RCT) and transports it to the liver for metabolism, while activating endothelial nitric oxide synthase (eNOS) to produce nitric oxide (NO), exerting antioxidant, anti-inflammatory, and vascular endothelial protective activities. High density lipoprotein (human) is promising for research of cardiovascular diseases, such as atherosclerosis .

HY-124750

NecroX-7	TNF Receptor Interleukin Related Toll-like Receptor (TLR) Reactive Oxygen Species (ROS)	Cardiovascular Disease Inflammation/Immunology
NecroX-7 is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 can be used graft-versus-host disease (GVHD) research .

HY-176224

Anti-virulence factor-IN-2	Bacterial	Infection Inflammation/Immunology
Anti-virulence factor-IN-2 (compound C7) is an inhibitor targeting the virulence factor KpsM in Escherichia coli. kpsM mediates the translocation of capsular polysaccharides to the cell surface, allowing kpsM-positive E. coli to escape the phagocytosis of the scavenger receptor Marco on liver Kupffer cells, leading to bacterial dissemination. kpsM-positive E. coli exacerbates ethanol-induced liver disease. Anti-virulence factor-IN-2 can inhibit the ethanol-induced liver disease model caused by kpsM-dependent capsid in mice and has anti-infective activity. Anti-virulence factor-IN-2 can be used for the study of alcoholic hepatitis .

HY-126726

KOdiA-PC	Biochemical Assay Reagents	Others
Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species that are cytotoxic and proatherogenic. Many of these species were recently isolated and purified from oxLDL and identified as phosphatidylcholine species containing fragmented oxidized short-chain fatty acid residues at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl)phosphatidylcholine or KOdiA-PC is one of the most potent CD36 ligands of the oxLDL species. KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle and may be one of the more important structural determinants of oxLDL.

Cat. No.	Product Name	Type

HY-126726

KOdiA-PC	Drug Delivery
Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species that are cytotoxic and proatherogenic. Many of these species were recently isolated and purified from oxLDL and identified as phosphatidylcholine species containing fragmented oxidized short-chain fatty acid residues at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl)phosphatidylcholine or KOdiA-PC is one of the most potent CD36 ligands of the oxLDL species. KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle and may be one of the more important structural determinants of oxLDL.

KOdiA-PC

Drug Delivery

Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species that are cytotoxic and proatherogenic. Many of these species were recently isolated and purified from oxLDL and identified as phosphatidylcholine species containing fragmented oxidized short-chain fatty acid residues at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl)phosphatidylcholine or KOdiA-PC is one of the most potent CD36 ligands of the oxLDL species. KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle and may be one of the more important structural determinants of oxLDL.

HY-NP203

High density lipoprotein (human) HDL (human)	Native Proteins
High density lipoprotein (HDL) (human) is a functional lipoprotein that binds to receptors such as scavenger receptor B1 (SR-B1), ABCA1 and ABCG1. High density lipoprotein (human) clears excess cholesterol from peripheral tissues through reverse cholesterol transport (RCT) and transports it to the liver for metabolism, while activating endothelial nitric oxide synthase (eNOS) to produce nitric oxide (NO), exerting antioxidant, anti-inflammatory, and vascular endothelial protective activities. High density lipoprotein (human) is promising for research of cardiovascular diseases, such as atherosclerosis .

High density lipoprotein (human)

HDL (human)

Native Proteins

High density lipoprotein (HDL) (human) is a functional lipoprotein that binds to receptors such as scavenger receptor B1 (SR-B1), ABCA1 and ABCG1. High density lipoprotein (human) clears excess cholesterol from peripheral tissues through reverse cholesterol transport (RCT) and transports it to the liver for metabolism, while activating endothelial nitric oxide synthase (eNOS) to produce nitric oxide (NO), exerting antioxidant, anti-inflammatory, and vascular endothelial protective activities. High density lipoprotein (human) is promising for research of cardiovascular diseases, such as atherosclerosis .

Cat. No.	Product Name	Target	Research Area

HY-P10453

Myr5A peptide	Peptides	Others
Myr5A peptide is an acylated peptide composed of apolipoprotein A1 (ApoA1) analog peptide 5A peptide coupled to the saturated fatty acid myristate. Myr5A peptide self-assembled into lipid nanostructures can be used to encapsulate anthracycline Doxorubicin (HY-15142A) and Valrubicin (HY-13772) for compound release studies in vitro .

HY-P11033

Pep2 Peptide	Transmembrane Glycoprotein	Cancer
Pep2 Peptide (also known as scavenger receptor B2) is a peptide ligand for the transmembrane glycoprotein CD36. Pep2 Peptide selectively binds to CD36 over HAS, IgG and CD44. Pep2 Peptide can be studied in research on enhancing delivery of anticancer agent .

Cat. No.	Product Name	Target	Research Area

HY-P990087

Zovostotug OR-2805	Inhibitory Antibodies	Inflammation/Immunology Cancer
Zovostotug is a human CD163 (scavenger receptor cysteine-rich (SRCR) type 1 M130) mAb .

HY-P99529

Valziflocept BAX1810; TAK-752	Fc Receptor (FcR)	Inflammation/Immunology
Valziflocept (BAX1810; TAK-752) is a recombinant soluble human FcγRIIb receptor that targets Fc and FcγR. FcγRs bind and neutralize pathogenic IgG, thus forming a "decoy" or "scavenger" receptor that can reduce the severity of autoimmune diseases. Valziflocept can be used in studies of autoimmune diseases such as systemic lupus erythematosus (SLE) .

Species:	Human (8) Rhesus Macaque (1) Mouse (3) Rat (3) Cynomolgus (1)
Tag:	His (14) Avi (1) Fc (4)
Source:	HEK293 (13) Sf9 insect cells (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P702553

	SREC-I/SCARF1 Protein, Human (HEK293, His) Acetyl LDL receptor; KIAA0149endothelial cells scavenger receptor; MGC47738; SCARF1; scavenger receptor class F, member 1; scavenger receptor expressed by endothelial cells 1; SREC1; SRECI; SREC-I; SRECscavenger receptor expressed by endothelial cells; SR-F1	Human	HEK293
	SREC-I/SCARF1 Protein acts as a multifunctional mediator, facilitating Ac-LDL binding and degradation, suggesting a role in lipid metabolism and adhesion. Involved in neurite-like outgrowth, it interacts with SREC2 and AVIL, forming a complex molecular network. The protein's diverse roles underscore its significance in various cellular processes beyond lipid metabolism. SREC-I/SCARF1 Protein, Human (HEK293, His) is the recombinant human-derived SREC-I/SCARF1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P76781

	CD204/MSR1 Protein, Human (HEK293, His) Macrophage scavenger receptor types I and II; SCARA1	Human	HEK293
	The CD204/MSR1 protein encoded by this gene consists of three isoforms. These integral membrane glycoproteins are mainly expressed in macrophages and play important roles in processes such as atherosclerosis and Alzheimer's disease. CD204/MSR1 Protein, Human (HEK293, His) is the recombinant human-derived CD204/MSR1 protein, expressed by HEK293 , with N-6*His labeled tag.

HY-P76782

	CD204/MSR1 Protein, Mouse (HEK293, His) 1 Publications Verification Macrophage scavenger receptor types I and II; SCARA1	Mouse	HEK293
	CD204/MSR1 Protein, a membrane glycoprotein, crucially contributes to cholesterol accumulation in arterial walls during atherogenesis. With two receptor subunits, it facilitates endocytosis of various macromolecules, including modified low-density lipoproteins (LDL). As a homotrimer, CD204/MSR1 engages in key interactions, including its association with MYO18A, highlighting its functional role in cellular processes. CD204/MSR1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD204/MSR1 protein, expressed by HEK293 , with N-His labeled tag.

HY-P76784

	CD204/MSR1 Protein, Rat (HEK293, His) Macrophage scavenger receptor types I and II; SCARA1	Rat	HEK293
	CD204/MSR1 Protein is a homo-trimeric transmembrane glycoprotein, holds key inflammatory roles in multiple pathophysiologic processes. MSR1 is highly expressed in lung, arteries, and adipose tissue. CD204/MSR1 Protein, Rat (HEK293, His) is the recombinant rat-derived CD204/MSR1 protein, expressed by HEK293 , with N-His labeled tag.

HY-P76279

	CL-P1/COLEC12 Protein, Rat (sf9, His) Collectin-12; Nurse cell scavenger receptor 2; CL-P1; Nsr2	Rat	Sf9 insect cells
	CL-P1/COLEC12 is a multifunctional scavenger receptor that effectively defends against microorganisms and promotes their binding and phagocytosis, covering Gram-positive and Gram-negative bacteria and yeast. In addition, it mediates the recognition, internalization, and degradation of oxidatively modified low-density lipoprotein (oxLDL) by vascular endothelial cells. CL-P1/COLEC12 Protein, Rat (sf9, His) is the recombinant rat-derived CL-P1/COLEC12 protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P76657

	SR-BI/SCARB1 Protein, Human (HEK293, His) scavenger receptor class B member 1; SRB1; CLA-1; CD36; CD36L1	Human	HEK293
	The SR-BI/SCARB1 protein is a multifunctional receptor that binds a variety of ligands, including phospholipids, cholesteryl esters, lipoproteins, phosphatidylserine, and apoptotic cells. As an HDL receptor, it crucially mediates selective cholesterol ether uptake and HDL-dependent cholesterol efflux. SR-BI/SCARB1 Protein, Human (HEK293, His) is the recombinant human-derived SR-BI/SCARB1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P78583

	MARCO Protein, Cynomolgus (HEK293, His) MARCO; SCARA2; Macrophage receptor with collagenous structure; scavenger receptor class A member 2	Cynomolgus	HEK293
	MARCO Protein exhibits a deficiency in conserved residue(s) essential for feature annotation propagation. MARCO Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived MARCO protein, expressed by HEK293 , with N-His labeled tag.

HY-P76783

	CD204/MSR1 Protein, Rat (HEK293, Fc) Macrophage scavenger receptor types I and II; SCARA1	Rat	HEK293
	CD204/MSR1 Protein is a homo-trimeric transmembrane glycoprotein, holds key inflammatory roles in multiple pathophysiologic processes. MSR1 is highly expressed in lung, arteries, and adipose tissue. CD204/MSR1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD204/MSR1 protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P77341

	CL-P1/COLEC12 Protein, Rhesus Macaque (sf9, His) Collectin-12; Nurse cell scavenger receptor 2; CL-P1; Nsr2	Rhesus Macaque	Sf9 insect cells
	Collectin-12 is a family of Ca²⁺-dependent, C-type lectins that contain a collagenous domain and function as recognition molecules for molecular patterns found on pathogens (1 - 4). CL-P1/COLEC12 Protein, Rhesus Macaque (sf9, His) is the recombinant Rhesus Macaque-derived CL-P1/COLEC12 protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P76656

	SR-BI/SCARB1 Protein, Human (HEK293, Fc) scavenger receptor class B member 1; SRB1; CLA-1; CD36; CD36L1	Human	HEK293
	The SR-BI/SCARB1 protein is a multifunctional receptor that binds a variety of ligands, including phospholipids, cholesteryl esters, lipoproteins, phosphatidylserine, and apoptotic cells. As an HDL receptor, it crucially mediates selective cholesterol ether uptake and HDL-dependent cholesterol efflux. SR-BI/SCARB1 Protein, Human (HEK293, Fc) is the recombinant human-derived SR-BI/SCARB1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P76658

	SR-BI/SCARB1 Protein, Human (HEK293, His-Fc) scavenger receptor class B member 1; SRB1; CLA-1; CD36; CD36L1	Human	HEK293
	The SR-BI/SCARB1 protein is a multifunctional receptor that binds a variety of ligands, including phospholipids, cholesteryl esters, lipoproteins, phosphatidylserine, and apoptotic cells. As an HDL receptor, it crucially mediates selective cholesterol ether uptake and HDL-dependent cholesterol efflux. SR-BI/SCARB1 Protein, Human (HEK293, His-Fc) is the recombinant human-derived SR-BI/SCARB1 protein, expressed by HEK293 , with C-hFc, C-His labeled tag.

HY-P76087

	SR-BI/SCARB1 Protein, Mouse (HEK293, His) scavenger receptor class B member 1; SRB1; SR-BI; CLA-1; CD36; CD36L1	Mouse	HEK293
	The SR-BI/SCARB1 protein is a multifunctional receptor that binds a variety of ligands, including phospholipids, cholesteryl esters, lipoproteins, phosphatidylserine, and apoptotic cells. Both isoform 1 and isoform 2 act as high-density lipoprotein (HDL) receptors, promoting cholesterol ether uptake and HDL-dependent cholesterol efflux. SR-BI/SCARB1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived SR-BI/SCARB1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P705125

	SR-BI/SCARB1 Protein, Human (Biotinylated, HEK293, His-Avi) scavenger receptor class B member 1; SRB1; CLA-1; CD36; CD36L1	Human	HEK293

HY-P76086

	SR-BI/SCARB1 Protein, Mouse (HEK293, His-Fc) scavenger receptor class B member 1; SRB1; SR-BI; CLA-1; CD36; CD36L1	Mouse	HEK293
	The SR-BI/SCARB1 protein is a multifunctional receptor that binds a variety of ligands, including phospholipids, cholesteryl esters, lipoproteins, phosphatidylserine, and apoptotic cells.Both isoform 1 and isoform 2 act as high-density lipoprotein (HDL) receptors, promoting cholesterol ether uptake and HDL-dependent cholesterol efflux.SR-BI/SCARB1 Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived SR-BI/SCARB1 protein, expressed by HEK293 , with C-hFc, C-His labeled tag.

HY-P79135

	Stabilin-2 Protein, Human (His) Stabilin-2; STAB2; FAS1 EGF-like and X-link domain-containing adhesion molecule 2; Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2; FEEL-2; Hyaluronan receptor for endocytosis; FEEL2; FELL; FEX2; HARE	Human	E. coli
	Stabilin-2 protein is a multifunctional phosphatidylserine and hyaluronic acid receptor that engulfs apoptotic cells and mediates hyaluronic acid endocytosis. As a systemic scavenger receptor, it binds various ligands and supports extracellular matrix turnover and body mobility. Stabilin-2 Protein, Human (His) is the recombinant human-derived Stabilin-2 protein, expressed by E. coli , with C-His labeled tag.

HY-P71278

	SCARB2/LIMP-2 Protein, Human (HEK293, His) Lysosome Membrane Protein 2; 85 kDa Lysosomal Membrane Sialoglycoprotein; LGP85; CD36 Antigen-Like 2; Lysosome Membrane Protein II; LIMP II; scavenger receptor Class B Member 2; CD36; SCARB2; CD36L2; LIMPII	Human	HEK293
	SCARB2/LIMP-2 Protein functions as a lysosomal receptor, specifically guiding glucosylceramidase (GBA1) to lysosomes. Additionally, it serves as a receptor for enterovirus 71, emphasizing its role in mediating cellular interactions during viral invasion and cellular entry processes. SCARB2/LIMP-2 Protein, Human (HEK293, His) is the recombinant human-derived SCARB2/LIMP-2 protein, expressed by HEK293 , with C-6*His labeled tag.

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HY-P80758

	CD204 Antibody 1 Publications Verification Macrophage scavenger receptor types I and II; Macrophage acetylated LDL receptor I and II; scavenger receptor class A member 1; CD204; MSR1; SCARA1	WB	Human, Mouse, Rat
	CD204 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to CD204.

HY-P81177

	CD163 Antibody 1 Publications Verification scavenger receptor cysteine-rich type 1 protein M130; CD 163; CD163 antigen; CD163 molecule; Hemoglobin scavenger receptor; M130; M130 antigen precursor; Macrophage associated antigen; MM130; C163A_HUMAN.	WB, IHC-P, IHC-F, ICC/IF	Human, Mouse
	CD163 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to CD163.

HY-P80066

	CD68 Antibody (YA798) CD 68 antibody; CD68 antibody; CD68 antigen antibody; CD68 molecule antibody; CD68_HUMAN antibody; DKFZp686M18236 antibody; gp11 antibody; Gp110 antibody; LAMP4 antibody; Macrophage antigen CD68 (microsialin) antibody; MACROPHAGE ANTIGEN CD68 antibody; Macrosialin antibody; SCARD1 antibody; scavenger receptor class D member 1 antibody	WB, IHC-P, FC	Human
	CD68 Antibody (YA798) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD68.

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