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electrostatic

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55

Inhibitors & Agonists

20

Fluorescent Dye

8

Biochemical Assay Reagents

10

Peptides

7

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2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-126437D

    Biochemical Assay Reagents Others
    Poly-L-lysine hydrobromide (MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine hydrobromide (MW 150000-300000) has good biocompatibility. Poly-L-lysine hydrobromide (MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface .
    Poly-L-lysine hydrobromide (MW >300000)
  • HY-126437B

    Biochemical Assay Reagents Others
    Poly-L-lysine (hydrobromide) (MW 70000-150000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine (hydrobromide) (MW 70000-150000) has good biocompatibility. Poly-L-lysine (hydrobromide) (MW 70000-150000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface .
    Poly-L-lysine hydrobromide (MW 70000-150000)
  • HY-D1225

    Fluorescent Dye
    Reactive red 180 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive red 180
  • HY-D1138

    Fluorescent Dye
    Reactive red 120 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive red 120
  • HY-D0476

    Fluorescent Dye
    C.I. Acid yellow 99 is an acidic yellow dye that combines with coconut shell pith through electrostatic and complexing reactions.
    C.I. Acid yellow 99
  • HY-D0584

    Fluorescent Dye
    Reactive orange 86 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive orange 86
  • HY-D0668

    Fluorescent Dye
    Reactive orange 13 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive orange 13
  • HY-D1243

    Fluorescent Dye
    Reactive yellow 3 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive yellow 3
  • HY-D0653

    Fluorescent Dye
    Reactive orange 35 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive orange 35
  • HY-D0691

    Fluorescent Dye
    Reactive yellow 25 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive yellow 25
  • HY-D0622

    Fluorescent Dye
    Reactive Green 19 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive Green 19
  • HY-D0514

    Fluorescent Dye
    Reactive blue 5 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive blue 5
  • HY-D0522

    Fluorescent Dye
    Reactive orange 16 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive orange 16
  • HY-D0639

    Fluorescent Dye
    Reactive Brown 23 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive Brown 23
  • HY-D0669

    Fluorescent Dye
    Reactive orange 4 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive orange 4
  • HY-D0661

    Fluorescent Dye
    Reactive red 45 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive red 45
  • HY-D0692

    Fluorescent Dye
    Reactive red 124 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive red 124
  • HY-D0700

    Fluorescent Dye
    Reactive red 24:1 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive red 24:1
  • HY-W154333

    Antibiotic Infection
    H-Arg-OtBu (dihydrochloride) is a membrane-targeting antimicrobial. H-Arg-OtBu (dihydrochloride) targets the negatively charged bacterial membrane via a combination of electrostatic and hydrophobic interactions. H-Arg-OtBu (dihydrochloride) can be used for bacterial infections diseases research .
    H-Arg-OtBu dihydrochloride
  • HY-145996

    Bacterial Infection
    STC314 is a small polyanion that interact electrostatically with histones. STC314 blocks disruption of lipid-bilayers by histones that inhibits the cytotoxic, platelet-activating and erythrocyte-damaging effects of histones. STC314 has anti-infective effects and can be uesd for sepsis research .
    STC314
  • HY-16468A

    ENT 01; MSI-1256 phosphate

    α-synuclein Neurological Disease
    Squalamine (phosphate) (Compound ENT-01) is an orally active neuroprotective agent. Squalamine (phosphate) can displace α-Syn that is bound electrostatically to nerve cell membranes and prevent aggregation of α-Syn. Squalamine (phosphate) can be used for the research of neurological disease, such as Parkinson’s disease .
    Squalamine phosphate
  • HY-130671A

    (R)-1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol sodium

    Liposome Others
    L-DPPG ((R)-1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol sodium) is a phospholipid targeting biological membranes. L-DPPG interacts with lipid bilayers through hydrophobic and electrostatic interactions. L-DPPG is used in research on drug delivery systems .
    L-DPPG
  • HY-P4101

    HIV Infection
    Cys(Npys)-TAT (47-57) is a peptide fragment of TAT peptide and it is able to interact with plasmid DNA electrostatically. Cys(Npys)-TAT (47-57) is corresponding to the transduction domain of TAT with an activated cysteine residue C. TAT is a small nuclear transcriptional activator protein encoded by HIV-1 .
    Cys(Npys)-TAT (47-57)
  • HY-W286362

    Palmitic acid anilide

    Bacterial Infection
    Palmitanilide (Palmitic acid anilide) is an antibacterial agent against Gram-positive bacteria. Palmitanilide can electrostatically bind to relevant components in the cell walls of Gram-positive bacteria (such as Bacillus cereus), alter the cell membrane structure, and affect the normal functions of the cells. Palmitanilide is promising for research of infectious diseases caused by Gram-positive bacteria .
    Palmitanilide
  • HY-D2864

    Fluorescent Dye Others
    Aza-CyBz is a selective NaCl-responsive fluorescent probe. Aza-CyBz visualizes plant salt stress by forming ordered aggregates with NaCl, leading to near-infrared fluorescence quenching. Aza-CyBz acts via electrostatic interaction between the cationic cyanine dye and NaCl to form J-aggregates, causing fluorescence quenching with a detection limit of 170 μM .
    Aza-CyBz
  • HY-23148

    N-Methylisatin

    Carboxylesterase (CES) Others
    1-Methylisatin is a potent and selective CE (carboxylesterases) inhibitor, with Kis of 38.2 and 5.38 μM for hiCE and hCE1, respectively. 1-Methylisatin interacts with Hb (human adult hemoglobin) by hydrophobic binding and electrostatic attraction. 1-Methylisatin can be used in the study of regulation of agent metabolism in vivo .
    1-Methylisatin
  • HY-Y0537B

    Biochemical Assay Reagents Mitochondrial Metabolism Metabolic Disease
    Potassium chloride, for molecular biology is potassium chloride that can be used in molecular biology. Potassium chloride, for molecular biology affects the stability of biological membranes by disrupting the electrostatic interactions between proteins and lipids. Potassium chloride, for molecular biology affects the solubility of myofibrillar proteins and the integrity of mitochondria. Potassium chloride, for molecular biology is commonly used in homogenization buffers and protein extraction procedures .
    Potassium chloride, for molecular biology
  • HY-120465

    HIV Infection
    ZINC36617540 is a novel Nef protein inhibitor with anti-HIV activity. ZINC36617540 exhibits superior binding affinity by binding to Nef protein. ZINC36617540 shows a similar binding mode to the prototype molecule B9 in molecular docking. The mechanism of action of ZINC36617540 mainly depends on its hydrophobic and electrostatic interactions with Nef protein .
    ZINC36617540
  • HY-130671B

    (S,S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol sodium

    Liposome Others
    (S,S)-DPPG is an enantiomeric isomer of L-DPPG. L-DPPG ((R)-1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol (sodium)) is a phospholipid targeting biological membranes. L-DPPG interacts with lipid bilayers through hydrophobic and electrostatic interactions. L-DPPG is used in research on drug delivery systems .
    (S,S)-DPPG
  • HY-126437A
    Poly-L-lysine hydrochloride
    1 Publications Verification

    Bacterial Infection Inflammation/Immunology
    Poly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine hydrochloride is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide. .
    Poly-L-lysine hydrochloride
  • HY-P5461

    Bacterial Others
    CHRG01 is a biological active peptide. (CHRG01 is derived from human b-defensin 3 (hBD3) C-terminal amino acids 54 to 67, with all Cys residues substituted with Ser. This substitution removes all disulfide bond linkages within the sequence. CHRG01, like hBD3, displays electrostatic-dependent antimicrobial properties.)
    CHRG01
  • HY-126437C

    Biochemical Assay Reagents Others
    Poly-L-lysine (hydrobromide) (MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine (hydrobromide) (MW 150000-300000) has good biocompatibility. Poly-L-lysine (hydrobromide) (MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface .
    Poly-L-lysine hydrobromide (MW 150000-300000)
  • HY-165427

    Liposome Cancer
    Lipid 11 (Compound Lipid 1) is a cationic lipid for nucleic acid delivery. Lipid 11 forms lipid nanoparticles (LNPs) through electrostatic binding with nucleic acids (such as ceDNA). Lipid 11 forms complexes with negatively charged nucleic acids via cationic amine groups, which can be endocytosed by cells to release nucleic acids for activity. Lipid 11 is promising for research of gene therapy drug delivery systems .
    Lipid 11
  • HY-155165

    Phosphodiesterase (PDE) Metabolic Disease
    Dazonone is a phosphodiesterase III inhibitor with the IC50 of 1.68 μM .
    Dazonone
  • HY-118260

    Adrenergic Receptor Endocrinology
    Phendioxan is a compound with binding activity at the α(1)-adrenaline receptor subtype. The facilitated membrane diffusion of phendioxan is thought to be associated with improved α(1d)-AR affinity. Docking simulations of phendioxan at biological targets supported the stoichiometric analysis and revealed the importance of polar, electrostatic, hydrophobic, and shape effects of its phenoxy terminal orthogonal substituents on ligand binding .
    Phendioxan
  • HY-159893

    Smo Hedgehog Apoptosis Cancer
    SMO-IN-5 ((Compound 25(B31)) is a potent and competitive inhibitor of smoothened (SMO) that can inhibit Hedgehog (Hh) signaling. SMO-IN-5 interacts with Smo through hydrogen bonds, hydrophobic interactions, and electrostatic forces. SMO-IN-5 inhibits PC cell proliferation, migration, and induces apoptosis by suppressing Gli1 expression. SMO-IN-5 exhibits antitumor activity in pancreatic cancer. .
    SMO-IN-5
  • HY-126437J

    PLL solution 0.01%, sterile-filtered, hydrobromide, MW 150000-300000, for cell culture

    Biochemical Assay Reagents Others
    Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) has good biocompatibility. Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface .
    Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000)
  • HY-126437E

    Biochemical Assay Reagents Influenza Virus Infection Cancer
    Poly-L-lysine hydrobromide (MW 15000-30000) is a cationic polymer composed of L-lysine monomers linked by peptide bonds. Poly-L-lysine hydrobromide (MW 15000-30000) interacts with negatively charged compounds through electrostatic interactions to form complexes. Poly-L-lysine hydrobromide (MW 15000-30000) can promote cell adhesion to solid substrates. Poly-L-lysine hydrobromide (MW 15000-30000) can be used for the study of gene manipulation of diseases such as cancer and influenza virus infection .
    Poly-L-lysine hydrobromide (MW 15000-30000)
  • HY-W145665

    Biochemical Assay Reagents Endogenous Metabolite Others
    Amylose is not a typical small-molecule ligand with a specific traditional receptor-binding target. It is a polysaccharide. In food science and biological systems, amylose can interact with proteins and free fatty acids through non-covalent forces like hydrophobic interactions and electrostatic interactions. For example, it can form a ternary complex with them, which is related to the structure and digestion of starch. It is widely studied in the fields of food science, carbohydrate metabolism, and is also relevant in research on controlling glycemic responses, as it affects starch digestion rate .
    Amylose
  • HY-126436D

    L-Ornithine homopolymer hydrochloride (MW 15000-30000)

    Biochemical Assay Reagents Metabolic Disease Endocrinology
    Poly-L-ornithine hydrochloride (MW 15000-30000) is a polycationic homopolymer composed of L-ornithine. Poly-L-ornithine hydrochloride (MW 15000-30000) adsorbs negatively charged species through electrostatic interactions. Poly-L-ornithine hydrochloride (MW 15000-30000) can be used as a key component of polyelectrolyte complexes to construct core-shell structure carriers to achieve controlled delivery of growth factors (such as rhBMP-2, FGF-1). Poly-L-ornithine hydrochloride (MW 15000-30000) is used in the study of diabetes and bone regeneration related diseases .
    Poly-L-ornithine hydrochloride (MW 15000-30000)
  • HY-D0163
    Methyl Green
    1 Publications Verification

    DNA Stain Others
    Methyl Green is a non-intercalating fluorescent labeling agent that selectively binds to the major groove of DNA. Methyl Green electrostatically interacts with the major groove of DNA through positively charged groups, exhibiting key activities such as high affinity, resistance to photobleaching, and stable fluorescence emission. Methyl Green can be directly measured by microscopy and flow cytometry, with peaks at 633 and 677 nm. Methyl Green can be used for fluorescent labeling of the nuclei of embryonic tissues or cells, or DNA staining and cell activity detection in gel electrophoresis[1][2][3].
    Methyl Green
  • HY-P1902

    Apoptosis Cardiovascular Disease
    Cardiotoxin Analog (CTX) IV (6-12) is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol) and can be isolated from the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) is a snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .
    Cardiotoxin Analog (CTX) IV (6-12)
  • HY-16468
    Squalamine
    1 Publications Verification

    MSI-1256; ENT-01 free acid

    Bacterial HBV FAK Dengue Virus Infection Neurological Disease Cancer
    Squalamine (MSI-1256) is an aminosterol compound with broad-spectrum antiviral activity. Squalamine makes cells less conducive to certain viral replication by altering the electrostatic interactions in the inner membrane of host cells. Squalamine also has antibacterial and antitumor activities. Squalamine has broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria, fungi and protozoa. Squalamine inhibits tumor-related angiogenesis and the growth of human breast cancer cells. Squalamine restores the function of enteric nervous system in Parkinson ,s disease mouse models .
    Squalamine
  • HY-D0006

    Fluorescent Dye Others
    Bathophenanthroline is a nitrogen-containing organic ligand that can form stable complexes with transition metal ions such as Ru 2+. In proteomics, Bathophenanthroline is often used for in-gel protein staining. The negatively charged sulfonic acid groups of Bathophenanthroline interact electrostatically with the positively charged amino acid residues of proteins, thereby achieving specific binding to proteins and enhancing the fluorescent signal of detection. Bathophenanthroline can be used for protein separation and detection in SDS-PAGE gels in the field of proteomics, as well as other fluorescence studies[1]. Ex/Em=532 nm/610 nm[1].
    Bathophenanthroline
  • HY-Y1123

    Glycinamide hydrochloride

    Amino Acid Derivatives Phosphatase Endocrinology
    2-Aminoacetamide hydrochloride (Glycinamide hydrochloride) is a derivative of Glycine (HY-Y0966). 2-Aminoacetamide hydrochloride forms cell-absorbable nanocomplexes with proteins (such as bovine serum albumin) through strong electrostatic interactions, promoting cellular uptake of related proteins. 2-Aminoacetamide hydrochloride synergizes with BMP2 to upregulate the expression of osteogenic marker genes (such as Col1a1, Alp, Runx2) and proteins (such as COL1, BSP), enhancing collagen synthesis. 2-Aminoacetamide hydrochloride synergizes with BMP2 to promote osteoblast differentiation in vitro and bone regeneration in vivo .
    2-Aminoacetamide hydrochloride
  • HY-P1902A

    Apoptosis Cardiovascular Disease
    Cardiotoxin Analog (CTX) IV (6-12) TFA is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol) and can be isolated from the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) TFA is a snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) TFA can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .
    Cardiotoxin Analog (CTX) IV (6-12) TFA
  • HY-D0948

    Fluorescent Dye Infection
    Celestine Blue is a electroactive indicator in DNA biosensors. Celestine Blue is strongly adsorbed on the spinel phases and CNT (carbon nanotubes), facilitates dispersion, acts as a capping agent and allows for the fabrication of spinel decorated CNT. Celestine Blue is an efficient charge transfer mediator, which allows for significant improvement of capacitive behavior. TiO2 nanoparticles doped with Celestine Blue can be used as a label in a sandwich immunoassay for the hepatitis C virus (HCV) core antigen .
    Celestine Blue
  • HY-W127378
    DOTAP methylsulfate
    Maximum Cited Publications
    9 Publications Verification

    1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate

    Liposome Others
    DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design[1][2].
    DOTAP methylsulfate
  • HY-178383

    Glycosidase Metabolic Disease
    α-Glucosidase-IN-98 is a potent orally active α-Glucosidase inhibitor with an IC₅₀ of 18.1 μM. α-Glucosidase-IN-98 reversibly binds with α-Glucosidase via hydrogen bonds, electrostatic interactions and hydrophobic effects, which induces significant conformational alterations in the secondary structure of α-Glucosidase. α-Glucosidase-IN-98 decreases postprandial hyperglycemia in starch (HY-B2225B)/sucrose (HY-B1779)-challenged mice. α-Glucosidase-IN-98 can be used for type 2 diabetes mellitus (T2DM) research .
    α-Glucosidase-IN-98
  • HY-P4121

    Potassium Channel Inflammation/Immunology Cancer
    L17E is an attenuated cationic amphiphilic lytic (ACAL) peptide that can be used to deliver a variety of macromolecules, including proteins, antibodies, and DNA nanostructures. L17E inserts and cleaves the membrane structure through electrostatic interaction, enabling intracellular escape. The efficiency of L17E-mediated delivery is strongly correlated with the expression level of KCNN4 (the gene encoding the calcium-activated potassium channel KCa3.1). L17E also promotes the cellular uptake of macromolecules by inducing micropinocytosis. L17E can be further optimized and improved through dimerization strategies and in combination with other delivery systems, such as nuclear localization signal peptides and cell membrane-coated nanoparticles .
    L17E

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