Search Result
Results for "
electrostatic
" in MedChemExpress (MCE) Product Catalog:
8
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-126437D
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Biochemical Assay Reagents
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Others
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Poly-L-lysine hydrobromide (MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine hydrobromide (MW 150000-300000) has good biocompatibility. Poly-L-lysine hydrobromide (MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface .
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- HY-126437B
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Biochemical Assay Reagents
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Others
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Poly-L-lysine (hydrobromide) (MW 70000-150000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine (hydrobromide) (MW 70000-150000) has good biocompatibility. Poly-L-lysine (hydrobromide) (MW 70000-150000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface .
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- HY-D1225
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Fluorescent Dye
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Reactive red 180 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D1138
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Fluorescent Dye
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Reactive red 120 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0476
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Fluorescent Dye
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C.I. Acid yellow 99 is an acidic yellow dye that combines with coconut shell pith through electrostatic and complexing reactions.
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- HY-D0584
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Fluorescent Dye
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Reactive orange 86 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0668
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Fluorescent Dye
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Reactive orange 13 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D1243
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Fluorescent Dye
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Reactive yellow 3 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0653
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Fluorescent Dye
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Reactive orange 35 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0691
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Fluorescent Dye
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Reactive yellow 25 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0622
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Fluorescent Dye
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Reactive Green 19 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0514
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Fluorescent Dye
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Reactive blue 5 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0522
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Fluorescent Dye
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Reactive orange 16 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0639
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Fluorescent Dye
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Reactive Brown 23 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0669
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Fluorescent Dye
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Reactive orange 4 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0661
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Fluorescent Dye
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Reactive red 45 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0692
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Fluorescent Dye
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Reactive red 124 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0700
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Fluorescent Dye
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Reactive red 24:1 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-W154333
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Antibiotic
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Infection
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H-Arg-OtBu (dihydrochloride) is a membrane-targeting antimicrobial. H-Arg-OtBu (dihydrochloride) targets the negatively charged bacterial membrane via a combination of electrostatic and hydrophobic interactions. H-Arg-OtBu (dihydrochloride) can be used for bacterial infections diseases research .
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- HY-145996
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Bacterial
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Infection
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STC314 is a small polyanion that interact electrostatically with histones. STC314 blocks disruption of lipid-bilayers by histones that inhibits the cytotoxic, platelet-activating and erythrocyte-damaging effects of histones. STC314 has anti-infective effects and can be uesd for sepsis research .
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- HY-16468A
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ENT 01; MSI-1256 phosphate
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α-synuclein
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Neurological Disease
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Squalamine (phosphate) (Compound ENT-01) is an orally active neuroprotective agent. Squalamine (phosphate) can displace α-Syn that is bound electrostatically to nerve cell membranes and prevent aggregation of α-Syn. Squalamine (phosphate) can be used for the research of neurological disease, such as Parkinson’s disease .
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- HY-130671A
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(R)-1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol sodium
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Liposome
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Others
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L-DPPG ((R)-1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol sodium) is a phospholipid targeting biological membranes. L-DPPG interacts with lipid bilayers through hydrophobic and electrostatic interactions. L-DPPG is used in research on drug delivery systems .
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- HY-P4101
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HIV
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Infection
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Cys(Npys)-TAT (47-57) is a peptide fragment of TAT peptide and it is able to interact with plasmid DNA electrostatically. Cys(Npys)-TAT (47-57) is corresponding to the transduction domain of TAT with an activated cysteine residue C. TAT is a small nuclear transcriptional activator protein encoded by HIV-1 .
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- HY-W286362
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Palmitic acid anilide
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Bacterial
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Infection
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Palmitanilide (Palmitic acid anilide) is an antibacterial agent against Gram-positive bacteria. Palmitanilide can electrostatically bind to relevant components in the cell walls of Gram-positive bacteria (such as Bacillus cereus), alter the cell membrane structure, and affect the normal functions of the cells. Palmitanilide is promising for research of infectious diseases caused by Gram-positive bacteria .
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- HY-D2864
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Fluorescent Dye
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Others
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Aza-CyBz is a selective NaCl-responsive fluorescent probe. Aza-CyBz visualizes plant salt stress by forming ordered aggregates with NaCl, leading to near-infrared fluorescence quenching. Aza-CyBz acts via electrostatic interaction between the cationic cyanine dye and NaCl to form J-aggregates, causing fluorescence quenching with a detection limit of 170 μM .
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- HY-23148
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N-Methylisatin
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Carboxylesterase (CES)
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Others
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1-Methylisatin is a potent and selective CE (carboxylesterases) inhibitor, with Kis of 38.2 and 5.38 μM for hiCE and hCE1, respectively. 1-Methylisatin interacts with Hb (human adult hemoglobin) by hydrophobic binding and electrostatic attraction. 1-Methylisatin can be used in the study of regulation of agent metabolism in vivo .
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- HY-Y0537B
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Biochemical Assay Reagents
Mitochondrial Metabolism
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Metabolic Disease
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Potassium chloride, for molecular biology is potassium chloride that can be used in molecular biology. Potassium chloride, for molecular biology affects the stability of biological membranes by disrupting the electrostatic interactions between proteins and lipids. Potassium chloride, for molecular biology affects the solubility of myofibrillar proteins and the integrity of mitochondria. Potassium chloride, for molecular biology is commonly used in homogenization buffers and protein extraction procedures .
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- HY-120465
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HIV
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Infection
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ZINC36617540 is a novel Nef protein inhibitor with anti-HIV activity. ZINC36617540 exhibits superior binding affinity by binding to Nef protein. ZINC36617540 shows a similar binding mode to the prototype molecule B9 in molecular docking. The mechanism of action of ZINC36617540 mainly depends on its hydrophobic and electrostatic interactions with Nef protein .
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- HY-130671B
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(S,S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol sodium
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Liposome
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Others
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(S,S)-DPPG is an enantiomeric isomer of L-DPPG. L-DPPG ((R)-1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol (sodium)) is a phospholipid targeting biological membranes. L-DPPG interacts with lipid bilayers through hydrophobic and electrostatic interactions. L-DPPG is used in research on drug delivery systems .
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- HY-126437A
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Bacterial
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Infection
Inflammation/Immunology
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Poly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine hydrochloride is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide. .
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- HY-P5461
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Bacterial
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Others
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CHRG01 is a biological active peptide. (CHRG01 is derived from human b-defensin 3 (hBD3) C-terminal amino acids 54 to 67, with all Cys residues substituted with Ser. This substitution removes all disulfide bond linkages within the sequence. CHRG01, like hBD3, displays electrostatic-dependent antimicrobial properties.)
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- HY-126437C
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Biochemical Assay Reagents
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Others
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Poly-L-lysine (hydrobromide) (MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine (hydrobromide) (MW 150000-300000) has good biocompatibility. Poly-L-lysine (hydrobromide) (MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface .
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- HY-165427
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Liposome
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Cancer
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Lipid 11 (Compound Lipid 1) is a cationic lipid for nucleic acid delivery. Lipid 11 forms lipid nanoparticles (LNPs) through electrostatic binding with nucleic acids (such as ceDNA). Lipid 11 forms complexes with negatively charged nucleic acids via cationic amine groups, which can be endocytosed by cells to release nucleic acids for activity. Lipid 11 is promising for research of gene therapy drug delivery systems .
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- HY-155165
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- HY-118260
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Adrenergic Receptor
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Endocrinology
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Phendioxan is a compound with binding activity at the α(1)-adrenaline receptor subtype. The facilitated membrane diffusion of phendioxan is thought to be associated with improved α(1d)-AR affinity. Docking simulations of phendioxan at biological targets supported the stoichiometric analysis and revealed the importance of polar, electrostatic, hydrophobic, and shape effects of its phenoxy terminal orthogonal substituents on ligand binding .
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- HY-159893
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Smo
Hedgehog
Apoptosis
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Cancer
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SMO-IN-5 ((Compound 25(B31)) is a potent and competitive inhibitor of smoothened (SMO) that can inhibit Hedgehog (Hh) signaling. SMO-IN-5 interacts with Smo through hydrogen bonds, hydrophobic interactions, and electrostatic forces. SMO-IN-5 inhibits PC cell proliferation, migration, and induces apoptosis by suppressing Gli1 expression. SMO-IN-5 exhibits antitumor activity in pancreatic cancer. .
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- HY-126437J
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PLL solution 0.01%, sterile-filtered, hydrobromide, MW 150000-300000, for cell culture
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Biochemical Assay Reagents
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Others
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Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) has good biocompatibility. Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface .
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- HY-126437E
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Biochemical Assay Reagents
Influenza Virus
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Infection
Cancer
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Poly-L-lysine hydrobromide (MW 15000-30000) is a cationic polymer composed of L-lysine monomers linked by peptide bonds. Poly-L-lysine hydrobromide (MW 15000-30000) interacts with negatively charged compounds through electrostatic interactions to form complexes. Poly-L-lysine hydrobromide (MW 15000-30000) can promote cell adhesion to solid substrates. Poly-L-lysine hydrobromide (MW 15000-30000) can be used for the study of gene manipulation of diseases such as cancer and influenza virus infection .
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- HY-W145665
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Biochemical Assay Reagents
Endogenous Metabolite
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Others
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Amylose is not a typical small-molecule ligand with a specific traditional receptor-binding target. It is a polysaccharide. In food science and biological systems, amylose can interact with proteins and free fatty acids through non-covalent forces like hydrophobic interactions and electrostatic interactions. For example, it can form a ternary complex with them, which is related to the structure and digestion of starch. It is widely studied in the fields of food science, carbohydrate metabolism, and is also relevant in research on controlling glycemic responses, as it affects starch digestion rate .
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- HY-126436D
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L-Ornithine homopolymer hydrochloride (MW 15000-30000)
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Biochemical Assay Reagents
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Metabolic Disease
Endocrinology
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Poly-L-ornithine hydrochloride (MW 15000-30000) is a polycationic homopolymer composed of L-ornithine. Poly-L-ornithine hydrochloride (MW 15000-30000) adsorbs negatively charged species through electrostatic interactions. Poly-L-ornithine hydrochloride (MW 15000-30000) can be used as a key component of polyelectrolyte complexes to construct core-shell structure carriers to achieve controlled delivery of growth factors (such as rhBMP-2, FGF-1). Poly-L-ornithine hydrochloride (MW 15000-30000) is used in the study of diabetes and bone regeneration related diseases .
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- HY-D0163
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DNA Stain
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Others
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Methyl Green is a non-intercalating fluorescent labeling agent that selectively binds to the major groove of DNA. Methyl Green electrostatically interacts with the major groove of DNA through positively charged groups, exhibiting key activities such as high affinity, resistance to photobleaching, and stable fluorescence emission. Methyl Green can be directly measured by microscopy and flow cytometry, with peaks at 633 and 677 nm. Methyl Green can be used for fluorescent labeling of the nuclei of embryonic tissues or cells, or DNA staining and cell activity detection in gel electrophoresis[1][2][3].
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- HY-P1902
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Apoptosis
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Cardiovascular Disease
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Cardiotoxin Analog (CTX) IV (6-12) is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol) and can be isolated from the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) is a snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .
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- HY-16468
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MSI-1256; ENT-01 free acid
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Bacterial
HBV
FAK
Dengue Virus
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Infection
Neurological Disease
Cancer
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Squalamine (MSI-1256) is an aminosterol compound with broad-spectrum antiviral activity. Squalamine makes cells less conducive to certain viral replication by altering the electrostatic interactions in the inner membrane of host cells. Squalamine also has antibacterial and antitumor activities. Squalamine has broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria, fungi and protozoa. Squalamine inhibits tumor-related angiogenesis and the growth of human breast cancer cells. Squalamine restores the function of enteric nervous system in Parkinson ,s disease mouse models .
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- HY-D0006
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Fluorescent Dye
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Others
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Bathophenanthroline is a nitrogen-containing organic ligand that can form stable complexes with transition metal ions such as Ru 2+. In proteomics, Bathophenanthroline is often used for in-gel protein staining. The negatively charged sulfonic acid groups of Bathophenanthroline interact electrostatically with the positively charged amino acid residues of proteins, thereby achieving specific binding to proteins and enhancing the fluorescent signal of detection. Bathophenanthroline can be used for protein separation and detection in SDS-PAGE gels in the field of proteomics, as well as other fluorescence studies[1]. Ex/Em=532 nm/610 nm[1].
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- HY-Y1123
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Glycinamide hydrochloride
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Amino Acid Derivatives
Phosphatase
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Endocrinology
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2-Aminoacetamide hydrochloride (Glycinamide hydrochloride) is a derivative of Glycine (HY-Y0966). 2-Aminoacetamide hydrochloride forms cell-absorbable nanocomplexes with proteins (such as bovine serum albumin) through strong electrostatic interactions, promoting cellular uptake of related proteins. 2-Aminoacetamide hydrochloride synergizes with BMP2 to upregulate the expression of osteogenic marker genes (such as Col1a1, Alp, Runx2) and proteins (such as COL1, BSP), enhancing collagen synthesis. 2-Aminoacetamide hydrochloride synergizes with BMP2 to promote osteoblast differentiation in vitro and bone regeneration in vivo .
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- HY-P1902A
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Apoptosis
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Cardiovascular Disease
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Cardiotoxin Analog (CTX) IV (6-12) TFA is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol) and can be isolated from the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) TFA is a snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) TFA can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .
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- HY-D0948
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Fluorescent Dye
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Infection
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Celestine Blue is a electroactive indicator in DNA biosensors. Celestine Blue is strongly adsorbed on the spinel phases and CNT (carbon nanotubes), facilitates dispersion, acts as a capping agent and allows for the fabrication of spinel decorated CNT. Celestine Blue is an efficient charge transfer mediator, which allows for significant improvement of capacitive behavior. TiO2 nanoparticles doped with Celestine Blue can be used as a label in a sandwich immunoassay for the hepatitis C virus (HCV) core antigen .
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- HY-W127378
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1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate
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Liposome
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Others
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DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design[1][2].
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- HY-178383
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Glycosidase
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Metabolic Disease
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α-Glucosidase-IN-98 is a potent orally active α-Glucosidase inhibitor with an IC₅₀ of 18.1 μM. α-Glucosidase-IN-98 reversibly binds with α-Glucosidase via hydrogen bonds, electrostatic interactions and hydrophobic effects, which induces significant conformational alterations in the secondary structure of α-Glucosidase. α-Glucosidase-IN-98 decreases postprandial hyperglycemia in starch (HY-B2225B)/sucrose (HY-B1779)-challenged mice. α-Glucosidase-IN-98 can be used for type 2 diabetes mellitus (T2DM) research .
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- HY-P4121
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Potassium Channel
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Inflammation/Immunology
Cancer
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L17E is an attenuated cationic amphiphilic lytic (ACAL) peptide that can be used to deliver a variety of macromolecules, including proteins, antibodies, and DNA nanostructures. L17E inserts and cleaves the membrane structure through electrostatic interaction, enabling intracellular escape. The efficiency of L17E-mediated delivery is strongly correlated with the expression level of KCNN4 (the gene encoding the calcium-activated potassium channel KCa3.1). L17E also promotes the cellular uptake of macromolecules by inducing micropinocytosis. L17E can be further optimized and improved through dimerization strategies and in combination with other delivery systems, such as nuclear localization signal peptides and cell membrane-coated nanoparticles .
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- HY-B0438R
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Reference Standards
Bacterial
Antibiotic
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Infection
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Spectinomycin (dihydrochloride) (Standard) is the analytical standard of Spectinomycin (dihydrochloride). This product is intended for research and analytical applications. Spectinomycin dihydrochloride is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride is also a noncompetitive inhibitor of td intron RNA with an Ki value of 7.2 mM[1]-[5].
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- HY-B1828
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Antibiotic
Bacterial
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Infection
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Spectinomycin is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin is also a noncompetitive inhibitor of td intron RNA .
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- HY-B1828A
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Spectinomycin hydrochloride hydrate
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Bacterial
Antibiotic
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Infection
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Spectinomycin dihydrochloride pentahydrate is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride pentahydrate acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride pentahydrate is also a noncompetitive inhibitor of td intron RNA with an Ki value of 7.2 mM - .
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- HY-B0438
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Bacterial
Antibiotic
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Infection
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Spectinomycin dihydrochloride is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride is also a noncompetitive inhibitor of td intron RNA with an Ki value of 7.2 mM - .
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- HY-W928617
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Antibiotic
Bacterial
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Infection
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Spectinomycin sulfate hydrate is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin sulfate hydrate acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin sulfate hydrate is also a noncompetitive inhibitor of td intron RNA with an Ki value of 7.2 mM - .
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| Cat. No. |
Product Name |
Type |
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- HY-D1225
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Dyes
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Reactive red 180 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D1138
-
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Dyes
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Reactive red 120 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0476
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Dyes
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C.I. Acid yellow 99 is an acidic yellow dye that combines with coconut shell pith through electrostatic and complexing reactions.
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- HY-D0584
-
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Dyes
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Reactive orange 86 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0668
-
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Dyes
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Reactive orange 13 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D1243
-
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Dyes
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Reactive yellow 3 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0653
-
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Dyes
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Reactive orange 35 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0691
-
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Dyes
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Reactive yellow 25 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0622
-
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Dyes
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Reactive Green 19 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0514
-
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Dyes
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Reactive blue 5 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0522
-
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Dyes
|
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Reactive orange 16 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0639
-
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Dyes
|
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Reactive Brown 23 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0669
-
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Dyes
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Reactive orange 4 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0661
-
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Dyes
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Reactive red 45 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0692
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Dyes
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Reactive red 124 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D0700
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Dyes
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Reactive red 24:1 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
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- HY-D2864
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Fluorescent Dyes/Probes
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Aza-CyBz is a selective NaCl-responsive fluorescent probe. Aza-CyBz visualizes plant salt stress by forming ordered aggregates with NaCl, leading to near-infrared fluorescence quenching. Aza-CyBz acts via electrostatic interaction between the cationic cyanine dye and NaCl to form J-aggregates, causing fluorescence quenching with a detection limit of 170 μM .
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- HY-D0163
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DNA Stain
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Methyl Green is a non-intercalating fluorescent labeling agent that selectively binds to the major groove of DNA. Methyl Green electrostatically interacts with the major groove of DNA through positively charged groups, exhibiting key activities such as high affinity, resistance to photobleaching, and stable fluorescence emission. Methyl Green can be directly measured by microscopy and flow cytometry, with peaks at 633 and 677 nm. Methyl Green can be used for fluorescent labeling of the nuclei of embryonic tissues or cells, or DNA staining and cell activity detection in gel electrophoresis[1][2][3].
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- HY-D0006
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Chromogenic Assays
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Bathophenanthroline is a nitrogen-containing organic ligand that can form stable complexes with transition metal ions such as Ru 2+. In proteomics, Bathophenanthroline is often used for in-gel protein staining. The negatively charged sulfonic acid groups of Bathophenanthroline interact electrostatically with the positively charged amino acid residues of proteins, thereby achieving specific binding to proteins and enhancing the fluorescent signal of detection. Bathophenanthroline can be used for protein separation and detection in SDS-PAGE gels in the field of proteomics, as well as other fluorescence studies[1]. Ex/Em=532 nm/610 nm[1].
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- HY-D0948
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Dyes
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Celestine Blue is a electroactive indicator in DNA biosensors. Celestine Blue is strongly adsorbed on the spinel phases and CNT (carbon nanotubes), facilitates dispersion, acts as a capping agent and allows for the fabrication of spinel decorated CNT. Celestine Blue is an efficient charge transfer mediator, which allows for significant improvement of capacitive behavior. TiO2 nanoparticles doped with Celestine Blue can be used as a label in a sandwich immunoassay for the hepatitis C virus (HCV) core antigen .
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| Cat. No. |
Product Name |
Type |
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- HY-Y0537B
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Buffer Reagents
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Potassium chloride, for molecular biology is potassium chloride that can be used in molecular biology. Potassium chloride, for molecular biology affects the stability of biological membranes by disrupting the electrostatic interactions between proteins and lipids. Potassium chloride, for molecular biology affects the solubility of myofibrillar proteins and the integrity of mitochondria. Potassium chloride, for molecular biology is commonly used in homogenization buffers and protein extraction procedures .
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- HY-126437A
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Drug Delivery
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Poly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine hydrochloride is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide. .
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- HY-126437J
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PLL solution 0.01%, sterile-filtered, hydrobromide, MW 150000-300000, for cell culture
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Cell Assay Reagents
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Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) has good biocompatibility. Poly-L-lysine solution (0.01%, sterile-filtered, MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface .
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- HY-126437E
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Cell Assay Reagents
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Poly-L-lysine hydrobromide (MW 15000-30000) is a cationic polymer composed of L-lysine monomers linked by peptide bonds. Poly-L-lysine hydrobromide (MW 15000-30000) interacts with negatively charged compounds through electrostatic interactions to form complexes. Poly-L-lysine hydrobromide (MW 15000-30000) can promote cell adhesion to solid substrates. Poly-L-lysine hydrobromide (MW 15000-30000) can be used for the study of gene manipulation of diseases such as cancer and influenza virus infection .
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- HY-W145665
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Biochemical Assay Reagents
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Amylose is not a typical small-molecule ligand with a specific traditional receptor-binding target. It is a polysaccharide. In food science and biological systems, amylose can interact with proteins and free fatty acids through non-covalent forces like hydrophobic interactions and electrostatic interactions. For example, it can form a ternary complex with them, which is related to the structure and digestion of starch. It is widely studied in the fields of food science, carbohydrate metabolism, and is also relevant in research on controlling glycemic responses, as it affects starch digestion rate .
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- HY-126436D
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L-Ornithine homopolymer hydrochloride (MW 15000-30000)
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Drug Delivery
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Poly-L-ornithine hydrochloride (MW 15000-30000) is a polycationic homopolymer composed of L-ornithine. Poly-L-ornithine hydrochloride (MW 15000-30000) adsorbs negatively charged species through electrostatic interactions. Poly-L-ornithine hydrochloride (MW 15000-30000) can be used as a key component of polyelectrolyte complexes to construct core-shell structure carriers to achieve controlled delivery of growth factors (such as rhBMP-2, FGF-1). Poly-L-ornithine hydrochloride (MW 15000-30000) is used in the study of diabetes and bone regeneration related diseases .
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- HY-Y1123
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Glycinamide hydrochloride
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Biochemical Assay Reagents
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2-Aminoacetamide hydrochloride (Glycinamide hydrochloride) is a derivative of Glycine (HY-Y0966). 2-Aminoacetamide hydrochloride forms cell-absorbable nanocomplexes with proteins (such as bovine serum albumin) through strong electrostatic interactions, promoting cellular uptake of related proteins. 2-Aminoacetamide hydrochloride synergizes with BMP2 to upregulate the expression of osteogenic marker genes (such as Col1a1, Alp, Runx2) and proteins (such as COL1, BSP), enhancing collagen synthesis. 2-Aminoacetamide hydrochloride synergizes with BMP2 to promote osteoblast differentiation in vitro and bone regeneration in vivo .
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- HY-W127378
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1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate
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Drug Delivery
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DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design[1][2].
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| Cat. No. |
Product Name |
Target |
Research Area |
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- HY-126437D
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Biochemical Assay Reagents
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Others
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Poly-L-lysine hydrobromide (MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine hydrobromide (MW 150000-300000) has good biocompatibility. Poly-L-lysine hydrobromide (MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface .
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- HY-126437B
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Biochemical Assay Reagents
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Others
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Poly-L-lysine (hydrobromide) (MW 70000-150000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine (hydrobromide) (MW 70000-150000) has good biocompatibility. Poly-L-lysine (hydrobromide) (MW 70000-150000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface .
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- HY-P10708A
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Peptides
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Cancer
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SVS-1 peptide acetate is an anticancer peptide. SVS-1 peptide acetate can selectively recognize cancer cells through electrostatic interactions, disrupt the cell membrane structure, and lead to cell death. Unlike antimicrobial peptides, the efficacy of SVS-1 peptide acetate occurs before complete neutralization of the membrane charge .
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- HY-P1902
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Apoptosis
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Cardiovascular Disease
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Cardiotoxin Analog (CTX) IV (6-12) is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol) and can be isolated from the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) is a snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .
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- HY-P1902A
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Apoptosis
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Cardiovascular Disease
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Cardiotoxin Analog (CTX) IV (6-12) TFA is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol) and can be isolated from the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) TFA is a snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) TFA can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .
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- HY-P5284
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Peptides
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Others
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RALA peptide is a cationic amphiphilic delivery agent targeting cell membranes, which forms nanoparticles through electrostatic interactions with anionic drugs. RALA peptide has pH-responsive binding properties, which can enhance the α-helical conformation in an acidic environment and destroy the endosomal membrane, promote the release of drugs into the cytoplasm, and exert efficient intracellular delivery activity. RALA peptide can be used in cancer research (enhancing the activity of bisphosphonates against prostate cancer and breast cancer cells) and bone tissue engineering (promoting osteoblast collagen deposition and extracellular matrix mineralization) .
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- HY-P4121
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Potassium Channel
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Inflammation/Immunology
Cancer
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L17E is an attenuated cationic amphiphilic lytic (ACAL) peptide that can be used to deliver a variety of macromolecules, including proteins, antibodies, and DNA nanostructures. L17E inserts and cleaves the membrane structure through electrostatic interaction, enabling intracellular escape. The efficiency of L17E-mediated delivery is strongly correlated with the expression level of KCNN4 (the gene encoding the calcium-activated potassium channel KCa3.1). L17E also promotes the cellular uptake of macromolecules by inducing micropinocytosis. L17E can be further optimized and improved through dimerization strategies and in combination with other delivery systems, such as nuclear localization signal peptides and cell membrane-coated nanoparticles .
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- HY-P4101
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HIV
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Infection
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Cys(Npys)-TAT (47-57) is a peptide fragment of TAT peptide and it is able to interact with plasmid DNA electrostatically. Cys(Npys)-TAT (47-57) is corresponding to the transduction domain of TAT with an activated cysteine residue C. TAT is a small nuclear transcriptional activator protein encoded by HIV-1 .
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- HY-P10708
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Peptides
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Cancer
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SVS-1 peptide is an anticancer peptide. SVS-1 peptide can selectively recognize cancer cells through electrostatic interactions, disrupt the cell membrane structure, and lead to cell death. Unlike antimicrobial peptides, the efficacy of SVS-1 peptide occurs before complete neutralization of the membrane charge .
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- HY-P5461
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Bacterial
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Others
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CHRG01 is a biological active peptide. (CHRG01 is derived from human b-defensin 3 (hBD3) C-terminal amino acids 54 to 67, with all Cys residues substituted with Ser. This substitution removes all disulfide bond linkages within the sequence. CHRG01, like hBD3, displays electrostatic-dependent antimicrobial properties.)
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
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- HY-W145665
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-
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- HY-P1902
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Cardiovascular Disease
Natural Products
Animals
Source classification
Disease Research Fields
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Apoptosis
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Cardiotoxin Analog (CTX) IV (6-12) is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol) and can be isolated from the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) is a snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .
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-
-
- HY-16468
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-
-
- HY-P1902A
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Pyrrole Alkaloids
Animals
Source classification
Other Diseases
Disease Research Fields
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Apoptosis
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Cardiotoxin Analog (CTX) IV (6-12) TFA is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol) and can be isolated from the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) TFA is a snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) TFA can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .
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-
-
- HY-B0438
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-
-
- HY-B0438R
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-
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- HY-B1828
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Microorganisms
Source classification
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Antibiotic
Bacterial
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Spectinomycin is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin is also a noncompetitive inhibitor of td intron RNA .
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-
| Cat. No. |
Product Name |
|
Classification |
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- HY-126437A
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Polymers
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Poly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine hydrochloride is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide. .
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-
- HY-W127378
-
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1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate
|
|
Cationic Lipids
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DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design[1][2].
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