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electric current-induced arterial thrombosis

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-11090A
    DPC423

    		Factor Xa Kallikrein Thrombin Ser/Thr Protease Cardiovascular Disease
    DPC423 is a selective and orally active factor Xa inhibitor with a Kis of 0.15 (human) and 0.3 (rabbit) nM. DPC423 exhibits Kis of 60, 61 and 6000 nM against human trypsin, plasma kallikrein and thrombin. DPC423 blocks the formation of prothrombinase complex, reduces thrombin production, inhibits fibrin formation and platelet activation. DPC423 has demonstrated antithrombotic effects in animal models, and when used in combination with Aspirin (HY-14654), it shows a strong synergistic effect. DPC423 can be used for the study of anticoagulation of arterial thrombosis .
    DPC423

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