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S1PL-IN-2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-124655
    S1PL-IN- 2

    		LPL Receptor Inflammation/Immunology
    S1PL-IN-2 (Compound 28) is a potent sphingosine-1-phosphate lyase (S1PL) inhibitor with an IC50 of 120 nM. S1PL-IN-2 shows an IC50 of 230 nM on HEK293 cells. S1PL-IN-2 block the conversion of Vitamin B6 into the active pyridoxal-4-phosphate cofactor required for S1P lyase activity. S1PL-IN-2 can be used for the researches of inflammation and immunology, such as rheumatoid arthritis .
    S1PL-IN- 2

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