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RWJ 60475

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-135477
    RWJ-60475

    		Phosphatase Bacterial Infection
    RWJ-60475 is a cell-permeable tyrosine phosphatase inhibitor. By inhibiting the activity of CD45/CD148 phosphatase, RWJ-60475 interferes with the phagocytic function of macrophages, thereby blocking the invasion of Legionella pneumophila into host cells and the transport of effector proteins. RWJ-60475 significantly reduces the uptake of bacterial particles by macrophages. RWJ-60475 can be used in the research of anti-infection targeting host factors .
    RWJ-60475

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