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Intrinsically Disordered Regions

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-114712
    SJ572403
    3 Publications Verification

    SJ403

    		 CDK Others
    SJ572403 (SJ403) is a p27 Kip1 inhibitor. SJ572403 has high specificity for specific regions within the D2 subdomain of p27-KID with a Kd value of 2.2 mM. SJ572403 can be used for the research of diseases associated with intrinsically disordered proteins (IDPs) .
    SJ572403
  • HY-178926
    RAGE406R

    		CCR TNF Receptor Interleukin Related Metabolic Disease Inflammation/Immunology Endocrinology
    RAGE406R is an orally active RAGE-DIAPH1 interaction antagonist. RAGE406R can bind to ctRAGE and prevent the formation of the RAGE-DIAPH1 complex and inhibit its interaction. RAGE406R can reduce the expression of CCL2, TNF, and IL-6 in THP1 cells. RAGE406R suppresses delayed-type hypersensitivity in T2D mice. RAGE406R can be used for the study of diabetes .
    RAGE406R

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