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Results for "

Hepcidin modulation

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

2

Peptides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P3494
    Hepcidin-25 (human)

    		Endogenous Metabolite Metabolic Disease
    Hepcidin-25 (human) is an iron metabolism modulator. Hepcidin-25 (human) shows anti-inflammatory and anti-bacterial activity via modulation of iron-mediated oxidant injury .
    Hepcidin-25 (human)
  • HY-P11260
    MD5

    		Ser/Thr Protease Endocrinology
    MD5 is a selective TMPRSS6 mimetic peptide inhibitor with an IC50 for recombinant human TMPRSS6 protein of 22 nM and a Ki of 3.4 nM. MD5 exhibits the significantly reduced inhibitory effect on Matriptase, with an IC50 of 352 nM and a Ki of 99.2 nM. MD5 exhibits good target specificity and only has a weak inhibitory effect on thrombin (Thrombin), with Ki of 120 nM. MD5 demonstrates good initial drugability and can be used for the study of iron overload diseases (such as hereditary hemochromatosis, β-thalassemia) .
    MD5

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