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Results for "

GLO1+Inhibitors

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-136684
    BrBzGCp2
    3 Publications Verification

    S-p-Bromobenzylglutathione cyclopentyl diester

    		 Glyoxalase (GLO) Neurological Disease Cancer
    BrBzGCp2 is a Glyoxalase 1 (GLO1) inhibitor, with a GC50 of 4.23 μM in HL-60 cells. BrBzGCp2 possesses antitumor and neuroprotective activity [1] .
    BrBzGCp2
  • HY-146655
    Glyoxalase I inhibitor 3

    		Glyoxalase (GLO) Cancer
    Glyoxalase I inhibitor 3 (compound 22g) is a potent glyoxalase I (GLO1) inhibitor with an IC50 of 0.011 µM. Glyoxalase I inhibitor 3 has the potential for the research of depression and anxiety [1].
    Glyoxalase I inhibitor 3
  • HY-146657
    4BAB

    		Glyoxalase (GLO) Cancer
    4BAB (compound 29) is an irreversible glyoxalase I (GLO1) inhibitor. 4BAB has anticancer effects [1].
    4BAB
  • HY-146654
    Glyoxalase I inhibitor 2

    		Glyoxalase (GLO) Cancer
    Glyoxalase I inhibitor 2 (compound 26) is a potent glyoxalase I (GLO1) inhibitor with an IC50 of 0.5 µM. Glyoxalase I inhibitor 2 has the potential for the research of depression and anxiety [1].
    Glyoxalase I inhibitor 2
  • HY-146653
    Glyoxalase I inhibitor 1

    		Glyoxalase (GLO) Cancer
    Glyoxalase I inhibitor 1 (compound 23) is a potent glyoxalase I (GLO1) inhibitor with an IC50 of 26 nM [1]. Glyoxalase I inhibitor 1 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Glyoxalase I inhibitor 1
  • HY-124824
    Methyl gerfelin

    		Glyoxalase (GLO) Others
    Methyl gerfelin inhibits osteoclast differentiation by binding 3 major cellular proteins: glyoxalase 1 (GLO1), sterol binding protein 2 (SCP2), and small glutamine-rich tetratricopeptide repeat containing protein A (SGTA). Methyl gerfelin is a potent GLO1 inhibitor related to the flavonoid class [1] .
    Methyl gerfelin

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