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DMT1 blocker 1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-126301
    DMT1 blocker 1
    2 Publications Verification

    		 Ferroportin Metabolic Disease
    DMT1 blocker 1 is an orally active blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64 μM. DMT1 blocker 1 inhibits intestinal cell absorption of non-heme iron, thereby alleviating iron overload by blocking the DMT1 transporter. DMT1 blocker 1 demonstrates significant efficacy in rodent models of acute iron hyperabsorption. DMT1 blocker 1 is useful for studying iron overload disorders such as hereditary hemochromatosis and thalassemia .
    DMT1 blocker 1

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