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CDK2-IN-49

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-179161
    CDK2-IN-49

    		CDK MDM-2/p53 Bcl-2 Family Apoptosis Cancer
    CDK2-IN-49 (Compound 5j) is a CDK2 inhibitor with an IC50 of 0.25 μM. CDK2-IN-49 shows potent activity against CDK7 with an IC50 of 0.14 μM. CDK2-IN-49 induces Apoptosis by raising the levels of p53 and Bax protein expression while reducing the amount of Bcl-2. CDK2-IN-49 inhibits cell division. CDK2-IN-49 can be used in the research of cancer .
    CDK2-IN-49

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