Acetyl lysine

By Targets:	Amino Acid Derivatives (2) Apoptosis (2) Bacterial (1) Endogenous Metabolite (6) Epigenetic Reader Domain (4) Fluorescent Dye (1) HDAC (1) Histone Acetyltransferase (1) Histone Demethylase (1) Isotope-Labeled Compounds (1)
By Research Areas:	Cancer (6) Infection (1) Metabolic Disease (5)

Targets Recommended: Acetyl-CoA Carboxylase Acetyl-CoA synthetase WNK Kinase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W048838

**Acetyl-L-lysine** 1 Publications Verification	Endogenous Metabolite	Metabolic Disease
Acetyl-L-lysine is an acetylated form of the amino acid L-lysine. Acetyl-L-lysine can participate in protein acylation processes, affecting protein functions such as stability and enzyme activity .

HY-113426S

*Nepsilon-acetyl-L-lysine-d8*	Isotope-Labeled Compounds Endogenous Metabolite	Others
Nepsilon-acetyl-L-lysine-d₈ is the deuterium labeled Nepsilon-Acetyl-L-lysine. Nepsilon-Acetyl-L-lysine, an endogenous metabolite, is an R-chain N-acetylated α amino acid .

HY-113426

Nepsilon-Acetyl-L-lysine 1 Publications Verification	Endogenous Metabolite	Metabolic Disease
Nepsilon-Acetyl-L-lysine, an endogenous metabolite, is an R-chain N-acetylated α amino acid .

HY-128730

Acetyl phosphate lithium potassium	Endogenous Metabolite Bacterial	Metabolic Disease
Acetyl phosphate lithium potassium is an endogenous metabolic product. Acetyl phosphate lithium potassium is a key substance in bacterial metabolic regulation, particularly in Lysine acetylation, and plays an important role in bacterial responses to environmental stress and adaptive reactions .

HY-108706

KDM2A/7A-IN-1	Histone Demethylase	Cancer
KDM2A/7A-IN-1 is a first-in-class, selective and cell-permeable inhibitor of *histone lysine* demethylases KDM2A/7A, with an IC₅₀** of 0.16 μM for KDM2A, exhibits 75 fold selevtivity over other JmjC lysine demethylases, and is inactive on methyl transferases, and histone acetyl transferases .

HY-W048838R

Acetyl-L-lysine (Standard)	Endogenous Metabolite	Metabolic Disease
Acetyl-L-lysine is an acetylated form of the amino acid L-lysine. Acetyl-L-lysine can participate in protein acylation processes, affecting protein functions such as stability and enzyme activity .

HY-113426R

*Nepsilon-Acetyl-L-lysine* (Standard)**	Endogenous Metabolite	Metabolic Disease
Nepsilon-Acetyl-L-lysine (Standard) is the analytical standard of Nepsilon-Acetyl-L-lysine. This product is intended for research and analytical applications. Nepsilon-Acetyl-L-lysine, an endogenous metabolite, is an R-chain N-acetylated α amino acid .

HY-W048215

N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-(2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetyl)-L-lysine	Amino Acid Derivatives	Others
N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-(2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetyl)-L-lysine is a lysine derivative .

HY-W131866

Methyl acetyl-L-lysinate hydrochloride	Amino Acid Derivatives	Others
Methyl acetyl-L-lysinate hydrochloride is a lysine derivative .

HY-144102

HDAC-IN-29	HDAC	Cancer
HDAC-IN-29 (compound 13b) is a potent pan-HDAC inhibitor. HDAC-IN-29 shows antitumor activity .

HY-136957

Fluorescein-6-isothiocyanate	Fluorescent Dye	Others
Fluorescein-6-isothiocyanate is a fluorescent isomeric haptenic probes with K_ds of 8.74, 2.72 and 1.88 for N-Acetyl-L-Lysine, normal mouse IgG and 4-4-20, respectively .

HY-19541

I-CBP112 3 Publications Verification	Histone Acetyltransferase Epigenetic Reader Domain	Cancer
I-CBP112, a chemical probe, is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor, that inhibits the CBP/p300 bromodomains, enhances acetylation by p300.

HY-136521

AZ13824374	Epigenetic Reader Domain	Cancer
AZ13824374 is a potent and selective ATAD2 bromodomain inhibitor (pIC₅₀ of 6.9 in HCT116 cells). AZ13824374 disrupts chromatin interactions and gene transcription by binding to the acetyl-lysine binding site of the ATAD2 bromodomain. AZ13824374 has anticancer activity against breast cancer .

HY-15658

GSK2801 2 Publications Verification	Epigenetic Reader Domain Apoptosis	Cancer
GSK2801, a chemical probe, is a potent, selective, orally active and cell active acetyl-lysine competitive BAZ2A and BAZ2B bromodomains inhibitor with K_d values of 136 nM and 257 nM, respectively. GSK2801 shows >50-fold selectivity for BAZ2A/B over BRD4 .

HY-107477

GSK8573	Epigenetic Reader Domain	Cancer
GSK8573 is an inactive control compound for GSK2801 (acetyl-lysine competitive inhibitor of BAZ2A and BAZ2B bromodomains). GSK8573 has binding activity to BRD9 with a K_d value of 1.04 μM and is inactive against BAZ2A/B and other bromodomain familiy. GSK8573 can be used as a structurally related negative control compound in biological experiments .

HY-111027

HDAC8-IN-13	Apoptosis	Infection
HDAC8-IN-13 is a novel histone deacetylase 8 (HDAC8) inhibitor with antiparasitic activity. HDAC8-IN-13 can effectively inhibit the acetyl-L-lysine deacetylase activity of schistosomes, affecting the parasite's infectivity. HDAC8-IN-13 can induce apoptosis and cause the death of schistosome cells. Through a specific structural basis design, HDAC8-IN-13 exhibits reduced affinity for human HDACs, thereby enhancing its selectivity .

Cat. No.	Product Name	Type

HY-136957

Fluorescein-6-isothiocyanate	Fluorescent Dyes/Probes
Fluorescein-6-isothiocyanate is a fluorescent isomeric haptenic probes with K_ds of 8.74, 2.72 and 1.88 for N-Acetyl-L-Lysine, normal mouse IgG and 4-4-20, respectively .

Cat. No.	Product Name	Target	Research Area

HY-W048215

N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-(2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetyl)-L-lysine	Amino Acid Derivatives	Others
N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-(2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetyl)-L-lysine is a lysine derivative .

HY-W131866

Methyl acetyl-L-lysinate hydrochloride	Amino Acid Derivatives	Others
Methyl acetyl-L-lysinate hydrochloride is a lysine derivative .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W048838

**Acetyl-L-lysine** 1 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Acetyl-L-lysine is an acetylated form of the amino acid L-lysine. Acetyl-L-lysine can participate in protein acylation processes, affecting protein functions such as stability and enzyme activity .

HY-113426

Nepsilon-Acetyl-L-lysine 1 Publications Verification	Classification of Application Fields Source classification Other Diseases Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Nepsilon-Acetyl-L-lysine, an endogenous metabolite, is an R-chain N-acetylated α amino acid .

HY-128730

Acetyl phosphate lithium potassium	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Bacterial
Acetyl phosphate lithium potassium is an endogenous metabolic product. Acetyl phosphate lithium potassium is a key substance in bacterial metabolic regulation, particularly in Lysine acetylation, and plays an important role in bacterial responses to environmental stress and adaptive reactions .

HY-W048838R

Acetyl-L-lysine (Standard)	Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
Acetyl-L-lysine is an acetylated form of the amino acid L-lysine. Acetyl-L-lysine can participate in protein acylation processes, affecting protein functions such as stability and enzyme activity .

HY-113426R

*Nepsilon-Acetyl-L-lysine* (Standard)**	Source classification Amino acids Endogenous metabolite	Endogenous Metabolite
Nepsilon-Acetyl-L-lysine (Standard) is the analytical standard of Nepsilon-Acetyl-L-lysine. This product is intended for research and analytical applications. Nepsilon-Acetyl-L-lysine, an endogenous metabolite, is an R-chain N-acetylated α amino acid .

Cat. No.	Product Name	Chemical Structure

HY-113426S

*Nepsilon-acetyl-L-lysine-d8*
Nepsilon-acetyl-L-lysine-d₈ is the deuterium labeled Nepsilon-Acetyl-L-lysine. Nepsilon-Acetyl-L-lysine, an endogenous metabolite, is an R-chain N-acetylated α amino acid .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P85737

	Acetyl Lysine Antibody (YA5429)	WB, IHC-P, ICC/IF, IP	Species independent
	Acetyl Lysine Antibody (YA5429) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Acetyl Lysine.

HY-P86733

	Acetyl Lysine Antibody (YA6425) Acetylated lysine; Acetyllysine; Ac-lysine; Ac lysine; Ac-K; Ac K; Ac-Lys; Ac Lys; Acetyl-lysine; Acetyl Lys; Ac-lysine;	IHC-P, IHC-F, ICC/IF, IF-Tissue, FC	Species independent
	Acetyl Lysine Antibody (YA6425) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to Acetyl Lysine.

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Acetyl lysine

Inhibitors & Agonists

Fluorescent Dye

Peptides

NaturalProducts

Isotope-Labeled Compounds

Antibodies

Natural
Products