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Results for "

β1AR

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (28) Apoptosis (1) Bacterial (3) Drug Metabolite (1) EGFR (1) Isotope-Labeled Compounds (4) Reference Standards (3)
By Research Areas:	Cancer (12) Cardiovascular Disease (18) Endocrinology (20) Inflammation/Immunology (6) Metabolic Disease (3) Neurological Disease (9)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0573S

Propranolol-d7 hydrochloride	Adrenergic Receptor	Cardiovascular Disease Neurological Disease Endocrinology
Propranolol-d₇ (hydrochloride) is a deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM . Propranolol hydrochloride is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

HY-15746

Dobutamine hydrochloride 4 Publications Verification	Adrenergic Receptor	Cardiovascular Disease Endocrinology Cancer
Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion ^[1] .

HY-15746A

Dobutamine 4 Publications Verification	Adrenergic Receptor	Cardiovascular Disease Endocrinology Cancer
Dobutamine is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine can increase cardiac output and correct hypoperfusion ^[1] .

HY-17497A

Acebutolol hydrochloride 3 Publications Verification	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Acebutolol hydrochloride is an orally active β1 adrenergic receptor (β1AR) antagonist. Acebutolol hydrochloride is used in the treatment of hypertension, angina pectoris and cardiac arrhythmias ^[1] .

HY-15746S

(rac)-Dobutamine-d4 hydrochloride	Isotope-Labeled Compounds Adrenergic Receptor	Cardiovascular Disease Endocrinology
(rac)-Dobutamine-d₄ (hydrochloride) is a labelled racemic Dobutamine hydrochloride. Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion ^[1] .

HY-15746B

Dobutamine tartrate	Adrenergic Receptor	Cardiovascular Disease Endocrinology Cancer
Dobutamine tartrate is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine tartrate is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine tartrate can increase cardiac output and correct hypoperfusion ^[1] .

HY-17497

Acebutolol	Adrenergic Receptor	Cardiovascular Disease
Acebutolol is an orally active β1 adrenergic receptor (β1AR) antagonist. Acebutolol is used for hypertension, angina pectoris and cardiac arrhythmias research ^[1] .

HY-15746S1

(rac)-Dobutamine-d6 hydrochloride	Isotope-Labeled Compounds Adrenergic Receptor	Cardiovascular Disease Endocrinology
(rac)-Dobutamine-d₆ (hydrochloride) is a labelled racemic Dobutamine hydrochloride. Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion ^[1] .

HY-15746R

Dobutamine hydrochloride (Standard)	Reference Standards Adrenergic Receptor	Cardiovascular Disease Endocrinology Cancer
Dobutamine (hydrochloride) (Standard) is the analytical standard of Dobutamine (hydrochloride). This product is intended for research and analytical applications. Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion ^[1] .

HY-17497AR

Acebutolol hydrochloride (Standard)	Reference Standards Adrenergic Receptor	Cardiovascular Disease Endocrinology
Acebutolol (hydrochloride) (Standard) is the analytical standard of Acebutolol (hydrochloride). This product is intended for research and analytical applications. Acebutolol hydrochloride is an orally active β1 adrenergic receptor (β1AR) antagonist. Acebutolol hydrochloride is used in the treatment of hypertension, angina pectoris and cardiac arrhythmias ^[1] .

HY-A0295

(R)-Propranolol hydrochloride 1 Publications Verification	Adrenergic Receptor	Cardiovascular Disease Neurological Disease Endocrinology
(R)-Propranolol hydrochloride is a less active enantiomer of the β-adrenoceptor antagonist propranolol (HY-B0573). Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β₁AR and β₂AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1].

HY-B1421

Ractopamine hydrochloride LY031537	Adrenergic Receptor	Metabolic Disease
Ractopamine (LY031537) hydrochloride is a potent β-adrenergic receptor (βAR) agonist with K_d value of ~25 nM for pig β₁AR and β₂AR. Ractopamine hydrochloride is linked to protein metabolism. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs ^[1] .

HY-130190

Butopamine LY131126	Adrenergic Receptor	Metabolic Disease
Butopamine is the active R/R stereoisomer butapamine of ractopamine hydrochloride. Butopamine exerts its physiological effects by stimulating β₁-adrenergic receptor (β₁AR) and β₂-adrenergic receptor (β₂AR) expressed in skeletal muscle and adipose tissue ^[1].

HY-106684A

Ridazolol hydrochloride	Adrenergic Receptor	Cardiovascular Disease
Ridazolol hydrochloride is a β-adrenergic receptor (βAR) antagonist. Ridazolol hydrochloride exhibits a high degree of selectivity for β-1 adrenergic receptor (β1AR) and possesses moderate intrinsic sympathomimetic activity (ISA). Ridazolol hydrochloride can competitively antagonize the relaxation effects induced by isoproterenol. Ridazolol hydrochloride is utilized in the research of cardiovascular diseases ^[1].

HY-106684

Ridazolol	Adrenergic Receptor	Cardiovascular Disease
Ridazolol is a β-adrenergic receptor (βAR) antagonist. Ridazolol exhibits a high degree of selectivity for β-1 adrenergic receptor (β1AR) and possesses moderate intrinsic sympathomimetic activity (ISA). Ridazolol can competitively antagonize the relaxation effects induced by isoproterenol. Ridazolol is utilized in the research of cardiovascular diseases ^[1].

HY-14300

Vilanterol 5 Publications Verification GW642444	Adrenergic Receptor	Inflammation/Immunology Endocrinology Cancer
Vilanterol (GW642444) is a long-acting β₂adrenergic receptor agonist. Vilanterol has pEC₅₀ values for β₂-AR, β₁-AR, and β₃-AR of 9.4, 6.4, and 6.1, respectively. Vilanterol selectively activates airway β₂ adrenergic receptors, increases cAMP and thus relaxes bronchial smooth muscle. Vilanterol can be used in asthma research ^[3][5].

HY-14300D

Vilanterol acetate GW642444 acetate	Adrenergic Receptor	Inflammation/Immunology
Vilanterol (GW642444) acetate is a long-acting β₂adrenergic receptor agonist. Vilanterol acetate has pEC₅₀ values for β₂-AR, β₁-AR, and β₃-AR of 9.4, 6.4, and 6.1, respectively. Vilanterol acetate selectively activates airway β₂ adrenergic receptors, increases cAMP and thus relaxes bronchial smooth muscle. Vilanterol acetate can be used in asthma research ^[1][2].

HY-14300A

Vilanterol trifenatate 5 Publications Verification GW642444 trifenatate	Adrenergic Receptor	Inflammation/Immunology Endocrinology Cancer
Vilanterol (GW642444) trifenatate is a long-acting β₂ adrenergic receptor agonist. Vilanterol trifenatate has pEC₅₀ values for β₂-AR, β₁-AR, and β₃-AR of 9.4, 6.4, and 6.1, respectively. Vilanterol trifenatate selectively activates airway β₂ adrenergic receptors, increases cAMP and thus relaxes bronchial smooth muscle. Vilanterol trifenatate can be used in asthma research ^[2][4].

HY-15844

AG-825 1 Publications Verification Tyrphostin AG-825	EGFR Apoptosis Adrenergic Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
AG-825 is a selective, ATP-competitive, tyrosine phosphorylation ErbB2 inhibitor with an IC₅₀ of 0.35 μM. AG825 significantly accelerates Apoptosis of human neutrophils. AG-825 increases *β1AR* density. AAG-825 has anticancer and anti-inflammatory activities. AAG-825 can be used in cardiovascular disease research ^[1] .

HY-B0573

Propranolol hydrochloride Maximum Cited Publications 37 Publications Verification	Adrenergic Receptor Bacterial	Cardiovascular Disease Neurological Disease Endocrinology Cancer
Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol hydrochloride inhibits [ ³H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM . Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

HY-B0573B

Propranolol Maximum Cited Publications 37 Publications Verification	Adrenergic Receptor Bacterial	Cardiovascular Disease Neurological Disease Endocrinology Cancer
Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol inhibits [ ³H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM . Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

HY-14300AS

Vilanterol-d4 trifenatate GW642444-d₄ trifenatate	Isotope-Labeled Compounds Adrenergic Receptor	Inflammation/Immunology Endocrinology
Vilanterol-d₄ (trifenatate) is deuterium labeled Vilanterol (trifenatate).Vilanterol (GW642444) acetate is a long-acting β₂ adrenergic receptor agonist. Vilanterol acetate has pEC₅₀ values for β₂-AR, β₁-AR, and β₃-AR of 9.4, 6.4, and 6.1, respectively. Vilanterol acetate selectively activates airway β₂ adrenergic receptors, increases cAMP and thus relaxes bronchial smooth muscle. Vilanterol acetate can be used in asthma research.

HY-113781

Ractopamine LY031537 free base	Adrenergic Receptor	Metabolic Disease
Ractopamine (LY031537 free base) is a potent β-adrenergic receptor (βAR) agonist with K_d value of ~25 nM for pig β₁AR and β₂AR. Ractopamine is linked to protein metabolism. Ractopamine is structurally similar to the natural catecholamines epinephrine and norepinephrine, and binds with high affinity to βAR in pig adipose and muscle tissue. Ractopamine can be used for researching to increase lean tissue growth and improve production efficiency in pigs ^[1] .

HY-B0573BS

Propranolol-d7	Adrenergic Receptor	Cardiovascular Disease Neurological Disease Endocrinology
Propranolol-d₇ is the deuterium labeled Propranolol. Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol inhibits [3H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM . Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

HY-B0573S1

Propranolol-d7 (ring-d7)	Adrenergic Receptor	Neurological Disease Endocrinology
Propranolol-d₇ (ring-d₇) is the deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM . Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

HY-B0573R

Propranolol hydrochloride (Standard)	Reference Standards Adrenergic Receptor Bacterial	Neurological Disease Endocrinology Cancer
Propranolol (hydrochloride) (Standard) is the analytical standard of Propranolol (hydrochloride). This product is intended for research and analytical applications. Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol hydrochloride inhibits [ ³H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM . Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

HY-W192276

(±)-Desisopropylpropranolol N-Desisopropylpropranolol	Drug Metabolite Adrenergic Receptor	Cardiovascular Disease Neurological Disease Endocrinology Cancer
(±)-Desisopropylpropranolol (N-Desisopropylpropranolol) is a metabolite of Propranolol (HY-B0573B). Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_is of 1.8 nM and 0.8 nM, respectively. Propranolol inhibits [ ³H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM. Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy ^[1] .

HY-14300S2

Vilanterol-d12 GW642444-d₁₂	Isotope-Labeled Compounds Adrenergic Receptor	Inflammation/Immunology Endocrinology Cancer
Vilanterol-d₁₂ (GW642444-d₁₂) is deuterium labeled Vilanterol. Vilanterol (GW642444) is a long-acting β₂-adrenoceptor (β₂-AR) agonist with 24 h activity. The pEC₅₀s for β₂-AR,β₁-AR and β₃-AR is 10.37±0.05, 6.98±0.03 and 7.36±0.03, respectively.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0573

Propranolol hydrochloride 35+ Cited Publications	Alkaloids Neurological Disease Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Endocrinology	Adrenergic Receptor Bacterial
Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol hydrochloride inhibits [ ³H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM . Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

HY-B0573B

Propranolol 35+ Cited Publications	Cardiovascular Disease Alkaloids Neurological Disease Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields	Adrenergic Receptor Bacterial
Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol inhibits [ ³H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM . Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

HY-B0573R

Propranolol hydrochloride (Standard)	Alkaloids Other Alkaloids Source classification Endogenous metabolite	Reference Standards Adrenergic Receptor Bacterial
Propranolol (hydrochloride) (Standard) is the analytical standard of Propranolol (hydrochloride). This product is intended for research and analytical applications. Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol hydrochloride inhibits [ ³H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM . Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

Cat. No.	Product Name	Chemical Structure

HY-B0573S

Propranolol-d7 hydrochloride
Propranolol-d₇ (hydrochloride) is a deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM . Propranolol hydrochloride is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

Propranolol-d7 hydrochloride

Propranolol-d₇ (hydrochloride) is a deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM . Propranolol hydrochloride is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

HY-15746S

(rac)-Dobutamine-d4 hydrochloride
(rac)-Dobutamine-d₄ (hydrochloride) is a labelled racemic Dobutamine hydrochloride. Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion ^[1] .

(rac)-Dobutamine-d4 hydrochloride

(rac)-Dobutamine-d₄ (hydrochloride) is a labelled racemic Dobutamine hydrochloride. Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion ^[1] .

HY-B0573BS

Propranolol-d7
Propranolol-d₇ is the deuterium labeled Propranolol. Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol inhibits [3H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM . Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

Propranolol-d7

Propranolol-d₇ is the deuterium labeled Propranolol. Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol inhibits [3H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM . Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

HY-B0573S1

Propranolol-d7 (ring-d7)
Propranolol-d₇ (ring-d₇) is the deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM . Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

Propranolol-d7 (ring-d7)

Propranolol-d₇ (ring-d₇) is the deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with K_i values of 1.8 nM and 0.8 nM, respectively ^[1]. Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC₅₀ of 12 nM . Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy .

HY-15746S1

(rac)-Dobutamine-d6 hydrochloride
(rac)-Dobutamine-d₆ (hydrochloride) is a labelled racemic Dobutamine hydrochloride. Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion ^[1] .

(rac)-Dobutamine-d6 hydrochloride

(rac)-Dobutamine-d₆ (hydrochloride) is a labelled racemic Dobutamine hydrochloride. Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion ^[1] .

HY-14300AS

Vilanterol-d4 trifenatate
Vilanterol-d₄ (trifenatate) is deuterium labeled Vilanterol (trifenatate).Vilanterol (GW642444) acetate is a long-acting β₂ adrenergic receptor agonist. Vilanterol acetate has pEC₅₀ values for β₂-AR, β₁-AR, and β₃-AR of 9.4, 6.4, and 6.1, respectively. Vilanterol acetate selectively activates airway β₂ adrenergic receptors, increases cAMP and thus relaxes bronchial smooth muscle. Vilanterol acetate can be used in asthma research.

Vilanterol-d4 trifenatate

Vilanterol-d₄ (trifenatate) is deuterium labeled Vilanterol (trifenatate).Vilanterol (GW642444) acetate is a long-acting β₂ adrenergic receptor agonist. Vilanterol acetate has pEC₅₀ values for β₂-AR, β₁-AR, and β₃-AR of 9.4, 6.4, and 6.1, respectively. Vilanterol acetate selectively activates airway β₂ adrenergic receptors, increases cAMP and thus relaxes bronchial smooth muscle. Vilanterol acetate can be used in asthma research.

HY-14300S2

Vilanterol-d12
Vilanterol-d₁₂ (GW642444-d₁₂) is deuterium labeled Vilanterol. Vilanterol (GW642444) is a long-acting β₂-adrenoceptor (β₂-AR) agonist with 24 h activity. The pEC₅₀s for β₂-AR,β₁-AR and β₃-AR is 10.37±0.05, 6.98±0.03 and 7.36±0.03, respectively.

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