2. Protein Tyrosine Kinase/RTK
  3. PDGFR
  4. Pegpleranib sodium

Pegpleranib sodium is a pegylated DNA aptamer that selectively binds to PDGF-BB and PDGF-AB homodimers and heterodimers, interrupting the interaction with their associated tyrosine kinase receptors.

For research use only. We do not sell to patients.

Gene Regulation Tool

Poly(oxy-1,2-ethanediyl), α-hydro-ω-methoxy-, 5'-ester with DNA d(C-A-G-G-C-(2'-deoxy-2'-fluoro)rU-A-(2'-deoxy-2'-fluoro)rC-rGm(oxyphosphinicooxy-1,2-ethanediyloxy-1,2-ethanediyloxy-1,2-ethanediyloxy-1,2-ethanediyloxy-1,2-ethanediyloxy-1,2-ethanediyloxyphosphinicooxy)C-G-T-A-rGm-A-rGm-C-A-(2'-deoxy-2'-fluoro)rU-(2'-deoxy-2'-fluoro)rC-rAm(oxyphosphinicooxy-1,2-ethanediyloxy-1,2-ethanediyloxy-1,2-ethanediyloxy-1,2-ethanediyloxy-1,2-ethanediyloxy-1,2-ethanediyloxyphosphinicooxy)T-G-A-T-(2'-deoxy-2'-fluoro)rC-(2'-deoxy-2'-fluoro)rC-(2'-deoxy-2'-fluoro)rU-rGm-(3'→3')-T) 5'-[6-[[2,6-bis(carboxyamino)-1-oxohexyl]amino]hexyl hydrogen phosphate] (2:1), sodium salt

Pegpleranib sodium Chemical Structure

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Pegpleranib sodium Related Antibodies

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Description

Pegpleranib sodium is a pegylated DNA aptamer that selectively binds to PDGF-BB and PDGF-AB homodimers and heterodimers, interrupting the interaction with their associated tyrosine kinase receptors.

SMILES

[Pegpleranib (sodium)]
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Pegpleranib sodium Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PegpleranibFovistaPDGFRPlatelet-derived growth factor receptorInhibitorinhibitorinhibit

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