1. Metabolic Enzyme/Protease
  2. Phospholipase
  3. ML256

ML256 is a covalent lipoprotein-associated phospholipase A2 (Lp-PLA2 inhibitor. ML256 can be used for the study of neoplasms harboring a constitutively active variant of one or both of KRAS or HRAS.

For research use only. We do not sell to patients.

ML256

ML256 Chemical Structure

CAS No. : 2415152-07-5

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Description

ML256 is a covalent lipoprotein-associated phospholipase A2 (Lp-PLA2 inhibitor. ML256 can be used for the study of neoplasms harboring a constitutively active variant of one or both of KRAS or HRAS[1].

IC50 & Target[1]

Lp-PLA2

 

Molecular Weight

424.49

Formula

C26H24N4O2

CAS No.
SMILES

O=C(N1CCN(CC1)C2=CC(C)=NC3=C2C=CC=C3)OC4=CC=C(C5=CC=CC=C5)C=N4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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ML256
Cat. No.:
HY-128762
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