Ywhah - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide Gene

Mus musculus

Gene ID: 22629 | Gene type: protein coding

About Ywhah

Summary

Enables actin binding activity; protein domain specific binding activity; and transmembrane transporter binding activity. Acts upstream of or within intracellular protein transport and negative regulation of dendrite morphogenesis. Located in cytoplasm. Is active in glutamatergic synapse and presynapse. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta). [provided by Alliance of Genome Resources, Apr 2022]

Ywhah Products(1)

mRNA	Protein	Name
NM_011738.2	NP_035868.1	14-3-3 protein eta

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables actin binding	IDA IDA: Inferred from direct assay	12176032	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	9299557	MGI
enables protein domain specific binding	IDA IDA: Inferred from direct assay	12446771	MGI
enables transmembrane transporter binding	IPI IPI: Inferred from physical interaction	16728661	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within intracellular protein transport	IDA IDA: Inferred from direct assay	12446771	MGI
acts upstream of or within negative regulation of dendrite morphogenesis	IDA IDA: Inferred from direct assay	9738002	MGI
involved in presynaptic modulation of chemical synaptic transmission	IDA IDA: Inferred from direct assay	15543142	MGI
involved in presynaptic modulation of chemical synaptic transmission	IMP IMP: Inferred from mutant phenotype	15543142	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in cerebellar granule cell to Purkinje cell synapse	IDA IDA: Inferred from direct assay	15543142	MGI
is active in cerebellar granule cell to Purkinje cell synapse	IMP IMP: Inferred from mutant phenotype	15543142	MGI
located in cytoplasm	IDA IDA: Inferred from direct assay	9738002	MGI
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	15543142	MGI
is active in presynapse	IDA IDA: Inferred from direct assay	15543142	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

14-3-3 protein eta

14-3-3 eta

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15943	YWHAH Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS19495	Ywhah Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS25989	Ywhah Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ywhah	NCBI	NCBI:7533

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