ERV3-1 - endogenous retrovirus group 3 member 1, envelope Gene

Homo sapiens

Also known as ERV3; ERVR; envR; ERV-R; HERVR; HERV-R

Gene ID: 2086 | Gene type: protein coding

About ERV3-1

Cytogenetic location: 7q11.21 Genomic coordinates (GRCh38): 7:64,990,356-65,006,687 (from NCBI)

This gene has 3 transcripts (splice variants), 136 orthologues and 5 paralogues. Ubiquitous expression in adrenal (RPKM 19.4), fat (RPKM 15.6) and 23 other tissues.

Summary

This gene contains sequence derived from endogenous retrovirus, and is therefore similar to multiple Other loci in the genome. Transcripts at this locus encode a conserved protein with a predicted signal peptide and similarity to the Env polyprotein. This protein is overexpressed in colorectal and Other cancers. [provided by RefSeq, Jan 2017]

ERV3-1 Products(2)

mRNA	Protein	Name
NM_001007253.4	NP_001007254.2	endogenous retrovirus group 3 member 1 Env polyprotein precursor
NM_001396062.1	NP_001382991.1	endogenous retrovirus group 3 member 1 Env polyprotein precursor

Protein Preferred Names

Protein Names

endogenous retrovirus group 3 member 1 Env polyprotein

ERV-R envelope protein

Related Diseases

Diseases

Alias

Choriocarcinoma

Chorioepithelioma

Heart Block, Congenital

Congenital Heart Block	Heart Block Congenital
Congenital Atrioventricular Block

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04517	ERV3-1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

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