2. Gene
  3. Chd4 - chromodomain helicase DNA binding protein 4 Gene

Chd4 - chromodomain helicase DNA binding protein 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Mi-2beta; mKIAA4075; D6Ertd380e; 9530019N15Rik

Gene ID: 107932 | Gene type: protein coding

About Chd4

Summary

Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity; histone deacetylase binding activity; and transcription coregulator binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and terminal button organization. Predicted to act upstream of or within chromatin organization. Located in nucleus. Part of NuRD complex and protein-DNA complex. Is expressed in several structures, including alimentary system; branchial arch; cardiovascular system; genitourinary system; and nervous system. Orthologous to human CHD4 (chromodomain helicase DNA binding protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Chd4 Products(8)

mRNA Protein Name
NM_001346610.2 NP_001333539.1 chromodomain-helicase-DNA-binding protein 4 isoform g
NM_001403592.1 NP_001390521.1 chromodomain-helicase-DNA-binding protein 4 isoform a
NM_001403593.1 NP_001390522.1 chromodomain-helicase-DNA-binding protein 4 isoform b
NM_001403594.1 NP_001390523.1 chromodomain-helicase-DNA-binding protein 4 isoform c
NM_001403595.1 NP_001390524.1 chromodomain-helicase-DNA-binding protein 4 isoform d
NM_001403596.1 NP_001390525.1 chromodomain-helicase-DNA-binding protein 4 isoform e
NM_001403597.1 NP_001390526.1 chromodomain-helicase-DNA-binding protein 4 isoform f
NM_001403598.1 NP_001390527.1 chromodomain-helicase-DNA-binding protein 4 isoform g
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription factor binding IPI
IPI: Inferred from physical interaction
33795231 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
21532573 MGI
enables transcription factor binding IPI
IPI: Inferred from physical interaction
15767674 MGI
Cellular Component GO Annotation Evidence Reference Source
part of NuRD complex IDA
IDA: Inferred from direct assay
22075476 MGI
located in nucleus IDA
IDA: Inferred from direct assay
20720167 MGI
part of protein-DNA complex IDA
IDA: Inferred from direct assay
21245044 MGI
part of protein-containing complex IDA
IDA: Inferred from direct assay
19796622 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chromodomain-helicase-DNA-binding protein 4

CHD-4

Mi-2 beta

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02609 CHD4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18917 Chd4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25407 Chd4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chd4 NCBI NCBI:1108