2. Gene
  3. E2f4 - E2F transcription factor 4 Gene

E2f4 - E2F transcription factor 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 2010111M04Rik

Gene ID: 104394 | Gene type: protein coding

About E2f4

Summary

Enables DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Acts upstream of or within several processes, including cell volume homeostasis; cilium assembly; and regulation of transcription, DNA-templated. Located in chromatin and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study otitis media. Orthologous to human E2F4 (E2F transcription factor 4). [provided by Alliance of Genome Resources, Apr 2022]

E2f4 Products(1)

mRNA Protein Name
NM_148952.1 NP_683754.1 transcription factor E2F4
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA binding IDA
IDA: Inferred from direct assay
10779331 MGI
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
15574595 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
11004506 MGI
enables chromatin binding IDA
IDA: Inferred from direct assay
22780989 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
7797074 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within animal organ morphogenesis IMP
IMP: Inferred from mutant phenotype
10983976 MGI
acts upstream of or within blood circulation IMP
IMP: Inferred from mutant phenotype
10983977 MGI
acts upstream of or within cell volume homeostasis IMP
IMP: Inferred from mutant phenotype
10983976 MGI
acts upstream of or within cilium assembly IMP
IMP: Inferred from mutant phenotype
17383628 MGI
acts upstream of or within epithelial cell development IMP
IMP: Inferred from mutant phenotype
17383628 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
7797074 MGI
acts upstream of or within regulation of cell population proliferation IDA
IDA: Inferred from direct assay
10779331 MGI
acts upstream of or within regulation of cell size IMP
IMP: Inferred from mutant phenotype
10983976 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11004506 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
15574595 MGI
Cellular Component GO Annotation Evidence Reference Source
located in chromatin IDA
IDA: Inferred from direct assay
12007404 MGI
located in nucleus IDA
IDA: Inferred from direct assay
10779331 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor E2F4

E2F-4

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-16667 HLM006474 Inhibitor 99.57% Unkown
HY-RS04113 E2F4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18033 E2f4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24507 E2f4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens E2f4 NCBI NCBI:1874