2. Gene
  3. DHFR - dihydrofolate reductase Gene

DHFR - dihydrofolate reductase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Oryctolagus cuniculus
Gene ID: 100359209 | Gene type: protein coding

About DHFR

Chromosome 11: 1,175,505-1,190,934 reverse strand.OryCun2.0:CM000800.1

This gene has 1 transcript (splice variant), 356 orthologues and 2 paralogues.

DHFR Products(1)

mRNA Protein Name
XM_051854075.1 XP_051710035.1 dihydrofolate reductase
Protein Preferred Names Protein Names

dihydrofolate reductase

Related Agents

Approval
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10820 Pemetrexed Inducer 99.95% Unkown
HY-10820A Pemetrexed disodium Inducer 99.95% Unkown
HY-18062 Pyrimethamine 99.90% Yes
HY-10446 Pralatrexate Inducer 99.23% Yes
HY-10373 Trimetrexate Inhibitor 99.22% Unkown
HY-B0806 Proguanil Inhibitor 99.84% Unkown
HY-I0447A Sodium 4-aminosalicylate dihydrate Inhibitor 99.95% Yes
HY-10820B Pemetrexed disodium heptahydrate 99.97% Unkown
HY-13781 Pemetrexed disodium hemipenta hydrate Inducer 99.72% Unkown
HY-B0806A Proguanil hydrochloride Inhibitor / Unkown
HY-10373A Trimetrexate trihydrochloride Inhibitor / Unkown
HY-10373B Trimetrexate isethionate Inhibitor / Unkown
Clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-14518 Aminopterin Antagonist ≥98.0% Phase 2
HY-106434 Piritrexim Inhibitor / Phase 2
HY-10824 Talotrexin / Phase 2
Pre-clinical Phase
Bioactive Molecules (62)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-116387 WR99210 Inhibitor 98.72% Unkown
HY-126316 Zapalog Modulator 98.16% Unkown
HY-107033 Tetroxoprim Inhibitor 99.32% Unkown
HY-W587663 4′-DTMP Inhibitor ≥97.0% Unkown
HY-139743 Aditoprime Inhibitor 99.68% Unkown
HY-B1902 Diaveridine 99.79% Unkown
HY-W003561 DHFR-IN-3 Inhibitor 99.64% Unkown
HY-137439 Fanotaprim 98.89% Unkown
HY-153007 DHFR-IN-5 Inhibitor 99.27% Unkown
HY-B0806AS1 Proguanil-d6 hydrochloride Inhibitor 98.73% Unkown
HY-B0806AS Proguanil-d4 hydrochloride Inhibitor / Unkown
HY-10820AS Pemetrexed-d5 disodium Inducer / Unkown
HY-10820S Pemetrexed-d5 / Unkown
HY-10824A Talotrexin monoammonium Inhibitor / Unkown
HY-10824B Talotrexin ammonium / Unkown
HY-116039 Epiroprim Inhibitor / Unkown
HY-116387A WR99210 hydrochloride Inhibitor / Unkown
HY-117791 (R)-Pralatrexate / Unkown
HY-122289 Metioprim Inhibitor / Unkown
HY-143236 DHFR-IN-1 Inhibitor / Unkown
HY-143408 OYYF-175 Inhibitor / Unkown
HY-147661 DHFR-IN-2 Inhibitor / Unkown
HY-149632 EGFR/HER2/DHFR-IN-2 Inhibitor / Unkown
HY-149633 EGFR/HER2/DHFR-IN-3 / Unkown
HY-149958 Antileishmanial agent-17 Inhibitor / Unkown
HY-151154 EGFR/HER2/DHFR-IN-1 Inhibitor / Unkown
HY-151156 EGFR/HER2-IN-6 / Unkown
HY-151158 EGFR/HER2-IN-7 Inhibitor / Unkown
HY-151159 DHFR-IN-4 Inhibitor 99.19% Unkown
HY-151161 EGFR/HER2-IN-8 Inhibitor / Unkown
HY-151458 VEGFR-2/DHFR-IN-1 Inhibitor / Unkown
HY-151459 VEGFR-2/DHFR-IN-2 Inhibitor / Unkown
HY-154807 DQn-1 Inhibitor / Unkown
HY-156122 DHFR-IN-8 Inhibitor / Unkown
HY-156123 DHFR-IN-9 Inhibitor / Unkown
HY-156859 NSC309401 dihydrochloride Inhibitor / Unkown
HY-162358 DHFR-IN-17 Inhibitor / Unkown
HY-162475 Fluorofolin Inhibitor / Unkown
HY-163722 EGFR/DHFR-IN-1 Inhibitor / Unkown
HY-168069 DHFR-IN-20 Inhibitor / Unkown
HY-19095 TNP-351 / Unkown
HY-B0806S1 Proguanil-d4 / Unkown
HY-N10791 Neobritannilactone B / Unkown
HY-RS03730 DHFR Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS03731 Dhfr Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS03732 Dhfr Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-115836 DDPO Inhibitor / Unkown
HY-118251 PD130883 Inhibitor / Unkown
HY-119613 Clociguanil Inhibitor / Unkown
HY-149200 Lysine-methotrexate / Unkown
HY-149459A Phototrexate Inhibitor / Unkown
HY-149699 DHFR-IN-12 Inhibitor / Unkown
HY-156412 DHFR-IN-10 Inhibitor / Unkown
HY-156414 DHFR-IN-11 Inhibitor / Unkown
HY-156859A NSC309401 Inhibitor / Unkown
HY-161010 DHFR-IN-13 Inhibitor / Unkown
HY-161063 DHFR-IN-14 Inhibitor / Unkown
HY-161064 DHFR-IN-15 Inhibitor / Unkown
HY-161292 DHFR-IN-16 Inhibitor / Unkown
HY-162656 DHFR-IN-19 Inhibitor / Unkown
HY-163725 DHFR-IN-18 Inhibitor / Unkown
HY-N3764 Diosbulbin C Activator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens DHFR NCBI NCBI:1719