2. Gene
  3. DDR2 - discoidin domain receptor tyrosine kinase 2 Gene

DDR2 - discoidin domain receptor tyrosine kinase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Sus scrofa
Gene ID: 100154199 | Gene type: protein coding

About DDR2

Primary_assembly 4: 87,756,168-87,911,296 reverse strand.Sscrofa11.1:CM000815.5

This gene has 2 transcripts (splice variants), 264 orthologues and 52 paralogues. Ubiquitous expression in subcutaneous adipose (RPKM 1.4), lung (RPKM 7.5) and 8 other tissues.

DDR2 Products(10)

mRNA Protein Name
XM_013988083.2 XP_013843537.2 discoidin domain-containing receptor 2 isoform X1
XM_021089500.1 XP_020945159.1 discoidin domain-containing receptor 2 isoform X5
XM_021089496.1 XP_020945155.1 discoidin domain-containing receptor 2 isoform X3
XM_021089499.1 XP_020945158.1 discoidin domain-containing receptor 2 isoform X5
XM_021089493.1 XP_020945152.1 discoidin domain-containing receptor 2 isoform X2
XM_021089501.1 XP_020945160.1 discoidin domain-containing receptor 2 isoform X6
XM_021089497.1 XP_020945156.1 discoidin domain-containing receptor 2 isoform X3
XM_021089498.1 XP_020945157.1 discoidin domain-containing receptor 2 isoform X4
XM_021089495.1 XP_020945154.1 discoidin domain-containing receptor 2 isoform X3
XM_021089494.1 XP_020945153.1 discoidin domain-containing receptor 2 isoform X3

DDR2 Protein Structure

FA58C

FA58C: cd00057 (96 - 248)

PKc_like

PKc_like: cl21453 (637 - 931)

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  • 936 a.a.
Protein Preferred Names Protein Names

discoidin domain-containing receptor 2

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-16961 Sitravatinib Inhibitor 99.57% Phase 3
HY-16961A Sitravatinib malate Inhibitor / Phase 3
Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-114169 WRG-28 Inhibitor 99.34% Unkown
HY-135401 VU6015929 Inhibitor 99.50% Unkown
HY-114311 FGFR1/DDR2 inhibitor 1 Inhibitor 98.26% Unkown
HY-114173 DDR1-IN-4 Inhibitor 98.19% Unkown
HY-156552 DDR1/2 inhibitor-2 Inhibitor 99.73% Unkown
HY-13979A DDR1-IN-1 dihydrochloride Inhibitor / Unkown
HY-14979A ML786 dihydrochloride Inhibitor / Unkown
HY-162102 DDR1-IN-8 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens DDR2 NCBI NCBI:4921
Mus musculus DDR2 NCBI NCBI:18214
Rattus norvegicus DDR2 NCBI NCBI:685781
Macaca mulatta DDR2 NCBI NCBI:720124